Showing entry for Hypoxia-Ischemia, Brain


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD010715
Disease NameHypoxia-Ischemia, Brain
Disease CUI IdC0752308
MeSH Codes C10   C14  
Disease Class NameNervous System Diseases; Cardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11137 BXGT007656 Microtubule-associated protein 2 4133 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P19634 BXGT008504 Sodium/hydrogen exchanger 1 6548 reviewed Transporter
P20810 BXGT008602 Calpastatin 831 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46821 BXGT010542 Microtubule-associated protein 1B 4131 reviewed Cellular structure
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P51617 BXGT010868 Interleukin-1 receptor-associated kinase 1 3654 reviewed Kinase
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P54764 BXGT011078 Ephrin type-A receptor 4 2043 reviewed Kinase
P54829 BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 84867 reviewed
P55211 BXGT011111 Caspase-9 842 reviewed Enzyme
Q00059 BXGT012512 Transcription factor A, mitochondrial 7019 reviewed
Q05586 BXGT012826 Glutamate receptor ionotropic, NMDA 1 2902 reviewed Ion channel
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 8851 reviewed Enzyme modulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q9H492 BXGT020472 Microtubule-associated proteins 1A/1B light chain 3A 84557 reviewed Cellular structure
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 51135 reviewed Kinase
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UER7 BXGT021672 Death domain-associated protein 6 1616 reviewed
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease