Showing entry for Skeletal muscle atrophy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009262
Disease NameSkeletal muscle atrophy
Disease CUI IdC0541794
MeSH Codes   
Disease Class Name
Semantic TypePathologic Function
Human Phenotype Ontology Id HP:0003011  
Human Phenotype Ontology TermAbnormality of the musculature
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A4D126 BXGT001208 D-ribitol-5-phosphate cytidylyltransferase 729920 reviewed
O00142 BXGT003883 Thymidine kinase 2, mitochondrial 7084 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O00459 BXGT003924 Phosphatidylinositol 3-kinase regulatory subunit beta 5296 reviewed Enzyme modulator
O14832 BXGT004104 Phytanoyl-CoA dioxygenase, peroxisomal 5264 reviewed
O15146 BXGT004131 Muscle, skeletal receptor tyrosine-protein kinase 4593 reviewed Kinase
O15269 BXGT004145 Serine palmitoyltransferase 1 10558 reviewed Enzyme
O43175 BXGT004575 D-3-phosphoglycerate dehydrogenase 26227 reviewed Enzyme
O43181 BXGT004576 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial 4724 reviewed
O43323 BXGT004587 Desert hedgehog protein 50846 reviewed
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
O60331 BXGT004872 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 23396 reviewed Kinase
O60930 BXGT004910 Ribonuclease H1 246243 reviewed
O60931 BXGT004911 Cystinosin 1497 reviewed
O95263 BXGT005366 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B 8622 reviewed
O95831 BXGT005399 Apoptosis-inducing factor 1, mitochondrial 9131 reviewed Enzyme
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02462 BXGT005881 Collagen alpha-1(IV) chain 1282 reviewed
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P02708 BXGT005927 Acetylcholine receptor subunit alpha 1134 reviewed Ion channel
P03886 BXGT006108 NADH-ubiquinone oxidoreductase chain 1 4535 reviewed Enzyme
P03905 BXGT006113 NADH-ubiquinone oxidoreductase chain 4 4538 reviewed Enzyme
P03915 BXGT006114 NADH-ubiquinone oxidoreductase chain 5 4540 reviewed Enzyme
P03923 BXGT006115 NADH-ubiquinone oxidoreductase chain 6 4541 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06753 BXGT006498 Tropomyosin alpha-3 chain 7170 reviewed Cellular structure
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P07686 BXGT006657 Beta-hexosaminidase subunit beta 3074 reviewed Enzyme
P07737 BXGT006663 Profilin-1 5216 reviewed
P09651 BXGT006913 Heterogeneous nuclear ribonucleoprotein A1 3178 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11230 BXGT007677 Acetylcholine receptor subunit beta 1140 reviewed Ion channel
P13497 BXGT007915 Bone morphogenetic protein 1 649 reviewed
P14920 BXGT008067 D-amino-acid oxidase 1610 reviewed
P15735 BXGT008151 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 5261 reviewed Kinase
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha 5566 reviewed Kinase
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P21817 BXGT008693 Ryanodine receptor 1 6261 reviewed Ion channel
P21860 BXGT008698 Receptor tyrosine-protein kinase erbB-3 2065 reviewed Kinase
P22626 BXGT008787 Heterogeneous nuclear ribonucleoproteins A2/B1 3181 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P30566 BXGT009446 Adenylosuccinate lyase 158 reviewed Enzyme
P35219 BXGT009797 Carbonic anhydrase-related protein 767 reviewed
P35499 BXGT009839 Sodium channel protein type 4 subunit alpha 6329 reviewed Ion channel
P36021 BXGT009893 Monocarboxylate transporter 8 6567 reviewed Transporter
P40926 BXGT010207 Malate dehydrogenase, mitochondrial 4191 reviewed Enzyme
P46019 BXGT010498 Phosphorylase b kinase regulatory subunit alpha, liver isoform 5256 reviewed Kinase
P46020 BXGT010499 Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform 5255 reviewed Kinase
P46976 BXGT010558 Glycogenin-1 2992 reviewed Enzyme
P49588 BXGT010713 Alanine--tRNA ligase, cytoplasmic 16 reviewed Nucleic acid binding
P49638 BXGT010720 Alpha-tocopherol transfer protein 7274 reviewed Transporter
P49773 BXGT010741 Histidine triad nucleotide-binding protein 1 3094 reviewed Enzyme
P50416 BXGT010797 Carnitine O-palmitoyltransferase 1, liver isoform 1374 reviewed Enzyme
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
P54764 BXGT011078 Ephrin type-A receptor 4 2043 reviewed Kinase
P54886 BXGT011092 Delta-1-pyrroline-5-carboxylate synthase 5832 reviewed Enzyme
P55072 BXGT011103 Transitional endoplasmic reticulum ATPase 7415 reviewed
P55263 BXGT011115 Adenosine kinase 132 reviewed Kinase
P58335 BXGT011233 Anthrax toxin receptor 2 118429 reviewed Receptor
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P63092 BXGT011495 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short 2778 reviewed
P68133 BXGT011578 Actin, alpha skeletal muscle 58 reviewed Cellular structure
P98155 BXGT012226 Very low-density lipoprotein receptor 7436 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q04446 BXGT012764 1,4-alpha-glucan-branching enzyme 2632 reviewed Enzyme
Q04844 BXGT012789 Acetylcholine receptor subunit epsilon 1145 reviewed Ion channel
Q06210 BXGT012864 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 2673 reviewed Enzyme
Q07001 BXGT012907 Acetylcholine receptor subunit delta 1144 reviewed Ion channel
Q09013 BXGT013023 Myotonin-protein kinase 1760 reviewed Kinase
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13148 BXGT013318 TAR DNA-binding protein 43 23435 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13501 BXGT013365 Sequestosome-1 8878 reviewed
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q14191 BXGT013452 Werner syndrome ATP-dependent helicase 7486 reviewed Enzyme
Q14203 BXGT013455 Dynactin subunit 1 1639 reviewed Chaperone
Q14204 BXGT013456 Cytoplasmic dynein 1 heavy chain 1 1778 reviewed Enzyme
Q15149 BXGT013547 Plectin 5339 reviewed Cellular structure
Q15303 BXGT013557 Receptor tyrosine-protein kinase erbB-4 2066 reviewed Kinase
Q15858 BXGT013610 Sodium channel protein type 9 subunit alpha 6335 reviewed Ion channel
Q6PI48 BXGT016471 Aspartate--tRNA ligase, mitochondrial 55157 reviewed Enzyme
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q8IWS0 BXGT018356 PHD finger protein 6 84295 reviewed Nucleic acid binding
Q8TCS8 BXGT018799 Polyribonucleotide nucleotidyltransferase 1, mitochondrial 87178 reviewed Enzyme
Q8WZ42 BXGT019023 Titin 7273 reviewed Kinase
Q8WZA1 BXGT019024 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 55624 reviewed
Q96C36 BXGT019631 Pyrroline-5-carboxylate reductase 2 29920 reviewed
Q96I59 BXGT019675 Probable asparagine--tRNA ligase, mitochondrial 79731 reviewed Enzyme
Q96PY6 BXGT019712 Serine/threonine-protein kinase Nek1 4750 reviewed Kinase
Q96T60 BXGT019745 Bifunctional polynucleotide phosphatase/kinase 11284 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99700 BXGT019949 Ataxin-2 6311 reviewed Nucleic acid binding
Q9BVA1 BXGT020142 Tubulin beta-2B chain 347733 reviewed
Q9H0F7 BXGT020435 ADP-ribosylation factor-like protein 6 84100 reviewed
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HCC0 BXGT020530 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial 64087 reviewed Enzyme
Q9HCR9 BXGT020537 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A 50940 reviewed
Q9NWM8 BXGT021233 Peptidyl-prolyl cis-trans isomerase FKBP14 55033 reviewed
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 51776 reviewed Kinase
Q9P2R7 BXGT021304 Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial 8803 reviewed Enzyme
Q9UBV7 BXGT021665 Beta-1,4-galactosyltransferase 7 11285 reviewed
Q9UGM6 BXGT021687 Tryptophan--tRNA ligase, mitochondrial 10352 reviewed
Q9UHD2 BXGT021697 Serine/threonine-protein kinase TBK1 29110 reviewed Kinase
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UI09 BXGT021710 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 55967 reviewed
Q9Y4D7 BXGT022275 Plexin-D1 23129 reviewed
Q9Y617 BXGT022314 Phosphoserine aminotransferase 29968 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
Q53GS7 BXGT023762 Nucleoporin GLE1 2733 reviewed Transporter
Q9H9S5 BXGT024623 Fukutin-related protein 79147 reviewed
Q9H040 BXGT024831 SprT-like domain-containing protein Spartan 83932 reviewed
A6NHR9 BXGT024875 Structural maintenance of chromosomes flexible hinge domain-containing protein 1 23347 reviewed
Q9Y4W6 BXGT025025 AFG3-like protein 2 10939 reviewed Enzyme
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96HY7 BXGT025609 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial 55526 reviewed
Q96MF2 BXGT025769 SH3 and cysteine-rich domain-containing protein 3 246329 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease