Showing entry for Beta-2 adrenergic receptor


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT011086
Protein NameBeta-2 adrenergic receptor
Uniport IdP54833
GeneADRB2
Gene Id403910
Domain7tm_1
Pfam PF00001  
OrganismCanis lupus familiaris (Dog) (Canis familiaris)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007190 activation of adenylate cyclase activity
Biological Process GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway
Biological Process GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway
Biological Process GO:0002032 desensitization of G protein-coupled receptor signaling pathway by arrestin
Biological Process GO:0045986 negative regulation of smooth muscle contraction
Biological Process GO:0002025 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure
Biological Process GO:1901098 positive regulation of autophagosome maturation
Biological Process GO:1904504 positive regulation of lipophagy
Biological Process GO:0043410 positive regulation of MAPK cascade
Biological Process GO:0006898 receptor-mediated endocytosis
molecular function GO:0004941 beta2-adrenergic receptor activity
molecular function GO:0051379 epinephrine binding
molecular function GO:0004930 G protein-coupled receptor activity
molecular function GO:0051380 norepinephrine binding
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0005769 early endosome
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0005871 Dopamine 153.18
BXGC0021893 Norepinephrine 169.07
BXGC0031384 Epinephrine 183.09
BXGC0041240 Atenolol 266.16
BXGC0042222 Propranolol 259.16
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein