Showing entry for Ras-related protein Rab-10



                       
General Target Information
BXGT IdBXGT011351
Protein NameRas-related protein Rab-10
Uniport IdP61026
GeneRAB10
Gene Id10890
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
4. Cellular Processes 4.1 Transport and catabolism hsa04144 Endocytosis
3. Environmental Information Processing 3.2 Signal transduction hsa04152 AMPK signaling pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0019882 antigen processing and presentation
Biological Process GO:0007409 axonogenesis
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0071786 endoplasmic reticulum tubular network organization
Biological Process GO:0016197 endosomal transport
Biological Process GO:0045200 establishment of neuroblast polarity
Biological Process GO:0097051 establishment of protein localization to endoplasmic reticulum membrane
Biological Process GO:0090150 establishment of protein localization to membrane
Biological Process GO:0043001 Golgi to plasma membrane protein transport
Biological Process GO:0006893 Golgi to plasma membrane transport
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:0030859 polarized epithelial cell differentiation
Biological Process GO:1903361 protein localization to basolateral plasma membrane
Biological Process GO:0072659 protein localization to plasma membrane
Biological Process GO:0009306 protein secretion
Biological Process GO:0045055 regulated exocytosis
Biological Process GO:0017157 regulation of exocytosis
Biological Process GO:0006904 vesicle docking involved in exocytosis
Biological Process GO:0016192 vesicle-mediated transport
molecular function GO:0098641 cadherin binding involved in cell-cell adhesion
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
molecular function GO:0031489 myosin V binding
cellular component GO:0005912 adherens junction
cellular component GO:0005929 cilium
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005856 cytoskeleton
cellular component GO:0005829 cytosol
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0071782 endoplasmic reticulum tubular network
cellular component GO:0005768 endosome
cellular component GO:0070382 exocytic vesicle
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0005794 Golgi apparatus
cellular component GO:0000139 Golgi membrane
cellular component GO:0032593 insulin-responsive compartment
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0030670 phagocytic vesicle membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0055037 recycling endosome
cellular component GO:0055038 recycling endosome membrane
cellular component GO:0030667 secretory granule membrane
cellular component GO:0008021 synaptic vesicle
cellular component GO:0005802 trans-Golgi network
Reactome
Pathway Id Pathway Name
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-6798695 Neutrophil degranulation
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0020456 BXGD001392 Hyperglycemia Nutritional and Metabolic Diseases
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0029463 BXGD002160 Osteosarcoma Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0279626 BXGD006657 Squamous cell carcinoma of esophagus Digestive System Diseases; Neoplasms
C0524587 BXGD009232 Mean Corpuscular Volume (result)
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0585442 BXGD009593 Osteosarcoma of bone Neoplasms
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1261502 BXGD011856 Finding of Mean Corpuscular Hemoglobin
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332986 BXGD012574 Childhood Osteosarcoma Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4511452 BXGD023002 Sporadic Parkinson disease Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0042376 Picropodophyllotoxin 414.13
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein