Showing entry for Cyclin-dependent kinase 18


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012908
Protein NameCyclin-dependent kinase 18
Uniport IdQ07002
GeneCDK18
Gene Id5129
DomainPkinase
Pfam PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006468 protein phosphorylation
Biological Process GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
molecular function GO:0005524 ATP binding
molecular function GO:0004693 cyclin-dependent protein serine/threonine kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0010054 BXGD000647 Coronary Arteriosclerosis Cardiovascular Diseases
C0010068 BXGD000648 Coronary heart disease Cardiovascular Diseases
C0011303 BXGD000712 Demyelinating Diseases Nervous System Diseases
C0017636 BXGD001131 Glioblastoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1956346 BXGD016627 Coronary Artery Disease Cardiovascular Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0040305 Indirubin 262.07
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
BXGC0050099 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 362.14
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein