Showing entry for Nuclear receptor subfamily 1 group D member 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013520
Protein NameNuclear receptor subfamily 1 group D member 2
Uniport IdQ14995
GeneNR1D2
Gene Id9975
DomainHormone_recep; zf-C4
Pfam PF00104   PF00105  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030154 cell differentiation
Biological Process GO:0048512 circadian behavior
Biological Process GO:0097009 energy homeostasis
Biological Process GO:0009755 hormone-mediated signaling pathway
Biological Process GO:0055088 lipid homeostasis
Biological Process GO:0050728 negative regulation of inflammatory response
Biological Process GO:0045892 negative regulation of transcription, DNA-templated
Biological Process GO:0000122 negative regulation of transcription by RNA polymerase II
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0042752 regulation of circadian rhythm
Biological Process GO:0050727 regulation of inflammatory response
Biological Process GO:0019216 regulation of lipid metabolic process
Biological Process GO:2001014 regulation of skeletal muscle cell differentiation
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006367 transcription initiation from RNA polymerase II promoter
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
molecular function GO:0004879 nuclear receptor activity
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0038023 signaling receptor activity
molecular function GO:0008134 transcription factor binding
molecular function GO:0008270 zinc ion binding
cellular component GO:0005737 cytoplasm
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0090575 RNA polymerase II transcription regulator complex
Reactome
Pathway Id Pathway Name
R-HSA-212436 Generic Transcription Pathway
R-HSA-383280 Nuclear Receptor transcription pathway
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002871 BXGD000132 Anemia Hemic and Lymphatic Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009324 BXGD000597 Ulcerative Colitis Digestive System Diseases
C0010403 BXGD000668 Cryoglobulinemia Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0014116 BXGD000892 Endocardial Cushion Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0017636 BXGD001131 Glioblastoma Neoplasms
C0019196 BXGD001301 Hepatitis C Digestive System Diseases; Infections
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023890 BXGD001713 Liver Cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0239946 BXGD005010 Fibrosis, Liver Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0524620 BXGD009236 Metabolic Syndrome X Nutritional and Metabolic Diseases
C0596887 BXGD009648 mathematical ability
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0740457 BXGD010000 Malignant neoplasm of kidney Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1378703 BXGD012933 Renal carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C1623038 BXGD013475 Cirrhosis Pathological Conditions, Signs and Symptoms
C1861453 BXGD016049 Pseudohyperkalemia Cardiff Nutritional and Metabolic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0008676 Haem 616.49
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein