Showing entry for Endocardial Cushion Defects


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD000892
Disease NameEndocardial Cushion Defects
Disease CUI IdC0014116
MeSH Codes C16   C14  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O95644 BXGT005389 Nuclear factor of activated T-cells, cytoplasmic 1 4772 reviewed Transcription factor
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06126 BXGT006412 T-cell surface glycoprotein CD1a 909 reviewed
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P41161 BXGT010229 ETS translocation variant 5 2119 reviewed Transcription factor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q04771 BXGT012783 Activin receptor type-1 90 reviewed Kinase
Q05655 BXGT012832 Protein kinase C delta type 5580 reviewed Kinase
Q14995 BXGT013520 Nuclear receptor subfamily 1 group D member 2 9975 reviewed Nuclear receptor
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B 29994 reviewed
Q9BVI0 BXGT023340 PHD finger protein 20 51230 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease