Showing entry for Transcriptional enhancer factor TEF-4


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT013579
Protein NameTranscriptional enhancer factor TEF-4
Uniport IdQ15562
GeneTEAD2
Gene Id8463
DomainTEA; YBD
Pfam PF01285   PF17725  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
3. Environmental Information Processing 3.2 Signal transduction hsa04390 Hippo signaling pathway
3. Environmental Information Processing 3.2 Signal transduction hsa04392 Hippo signaling pathway - multiple species
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071300 cellular response to retinoic acid
Biological Process GO:0003143 embryonic heart tube morphogenesis
Biological Process GO:0048568 embryonic organ development
Biological Process GO:0035329 hippo signaling
Biological Process GO:0048368 lateral mesoderm development
Biological Process GO:0060548 negative regulation of cell death
Biological Process GO:0001843 neural tube closure
Biological Process GO:0030903 notochord development
Biological Process GO:0048339 paraxial mesoderm development
Biological Process GO:0045893 positive regulation of transcription, DNA-templated
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0065003 protein-containing complex assembly
Biological Process GO:2000736 regulation of stem cell differentiation
Biological Process GO:0006355 regulation of transcription, DNA-templated
Biological Process GO:0006367 transcription initiation from RNA polymerase II promoter
Biological Process GO:0001570 vasculogenesis
molecular function GO:0097718 disordered domain specific binding
molecular function GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
molecular function GO:0003700 DNA-binding transcription factor activity
molecular function GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:1990837 sequence-specific double-stranded DNA binding
molecular function GO:0001223 transcription coactivator binding
cellular component GO:0005829 cytosol
cellular component GO:0043231 intracellular membrane-bounded organelle
cellular component GO:0000790 nuclear chromatin
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0071149 TEAD-2-YAP complex
cellular component GO:0005667 transcription regulator complex
Reactome
Pathway Id Pathway Name
R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression
R-HSA-212436 Generic Transcription Pathway
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-8878159 Transcriptional regulation by RUNX3
R-HSA-8951671 RUNX3 regulates YAP1-mediated transcription
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027832 BXGD002048 Neurofibromatosis 2 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0206695 BXGD004246 Carcinoma, Neuroendocrine Neoplasms
C0268596 BXGD006000 Multiple Acyl Coenzyme A Dehydrogenase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0555198 BXGD009432 Malignant Glioma Neoplasms
C0685938 BXGD009829 Malignant neoplasm of gastrointestinal tract Digestive System Diseases; Neoplasms
C1136382 BXGD011717 Sclerocystic Ovaries Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0002144 Tetradecanoic acid 228.37
BXGC0005513 Hexadecanoic acid 256.42
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein