adisease

Showing entry for Malignant Glioma

General Disease Information
BXGD Id	BXGD009432
Disease Name	Malignant Glioma
Disease CUI Id	C0555198
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:14566
Disease Ontology Class Name	disease of cellular proliferation
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00194	BXGT003892	Ras-related protein Rab-27B	5874	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00418	BXGT003918	Eukaryotic elongation factor 2 kinase	29904	reviewed	Kinase
O00459	BXGT003924	Phosphatidylinositol 3-kinase regulatory subunit beta	5296	reviewed	Enzyme modulator
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14763	BXGT004093	Tumor necrosis factor receptor superfamily member 10B	8795	reviewed
O14907	BXGT004109	Tax1-binding protein 3	30851	reviewed
O14980	BXGT004119	Exportin-1	7514	reviewed	Receptor
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15151	BXGT004132	Protein Mdm4	4194	reviewed	Nucleic acid binding
O15164	BXGT004133	Transcription intermediary factor 1-alpha	8805	reviewed
O15297	BXGT004149	Protein phosphatase 1D	8493	reviewed	Enzyme
O15392	BXGT004162	Baculoviral IAP repeat-containing protein 5	332	reviewed	Enzyme modulator
O15438	BXGT004168	Canalicular multispecific organic anion transporter 2	8714	reviewed	Transporter
O15540	BXGT004178	Fatty acid-binding protein, brain	2173	reviewed
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43809	BXGT004627	Cleavage and polyadenylation specificity factor subunit 5	11051	reviewed	Nucleic acid binding
O60242	BXGT004861	Adhesion G protein-coupled receptor B3	577	reviewed	G-protein coupled receptor
O60260	BXGT004864	E3 ubiquitin-protein ligase parkin	5071	reviewed	Enzyme
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O60858	BXGT004903	E3 ubiquitin-protein ligase TRIM13	10206	reviewed
O75084	BXGT005098	Frizzled-7	8324	reviewed	G-protein coupled receptor
O75164	BXGT005104	Lysine-specific demethylase 4A	9682	reviewed
O75473	BXGT005129	Leucine-rich repeat-containing G-protein coupled receptor 5	8549	reviewed	G-protein coupled receptor
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
O94813	BXGT005337	Slit homolog 2 protein	9353	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O94925	BXGT005342	Glutaminase kidney isoform, mitochondrial	2744	reviewed	Enzyme
O95407	BXGT005380	Tumor necrosis factor receptor superfamily member 6B	8771	reviewed
O95619	BXGT005385	YEATS domain-containing protein 4	8089	reviewed	Nucleic acid binding
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
O95931	BXGT005407	Chromobox protein homolog 7	23492	reviewed	Epigenetic regulator
O95970	BXGT005409	Leucine-rich glioma-inactivated protein 1	9211	reviewed
P00338	BXGT005504	L-lactate dehydrogenase A chain	3939	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00505	BXGT005560	Aspartate aminotransferase, mitochondrial	2806	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01106	BXGT005730	Myc proto-oncogene protein	4609	reviewed	Transcription factor
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02786	BXGT005961	Transferrin receptor protein 1	7037	reviewed	Enzyme
P02794	BXGT005967	Ferritin heavy chain	2495	reviewed	Storage
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04004	BXGT006125	Vitronectin	7448	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04083	BXGT006147	Annexin A1	301	reviewed
P04183	BXGT006166	Thymidine kinase, cytosolic	7083	reviewed	Kinase
P04626	BXGT006238	Receptor tyrosine-protein kinase erbB-2	2064	reviewed	Kinase
P04629	BXGT006239	High affinity nerve growth factor receptor	4914	reviewed	Kinase
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05023	BXGT006294	Sodium/potassium-transporting ATPase subunit alpha-1	476	reviewed	Transporter
P05090	BXGT006311	Apolipoprotein D	347	reviewed
P05106	BXGT006315	Integrin beta-3	3690	reviewed	Receptor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P05413	BXGT006355	Fatty acid-binding protein, heart	2170	reviewed
P06493	BXGT006445	Cyclin-dependent kinase 1	983	reviewed	Kinase
P06729	BXGT006486	T-cell surface antigen CD2	914	reviewed
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P06753	BXGT006498	Tropomyosin alpha-3 chain	7170	reviewed	Cellular structure
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P06858	BXGT006515	Lipoprotein lipase	4023	reviewed	Enzyme
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07237	BXGT006576	Protein disulfide-isomerase	5034	reviewed
P07355	BXGT006609	Annexin A2	302	reviewed
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P08138	BXGT006729	Tumor necrosis factor receptor superfamily member 16	4804	reviewed	Receptor
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P08670	BXGT006810	Vimentin	7431	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09382	BXGT006882	Galectin-1	3956	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10398	BXGT007564	Serine/threonine-protein kinase A-Raf	369	reviewed	Kinase
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	3309	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11388	BXGT007697	DNA topoisomerase 2-alpha	7153	reviewed
P11802	BXGT007750	Cyclin-dependent kinase 4	1019	reviewed	Kinase
P12004	BXGT007766	Proliferating cell nuclear antigen	5111	reviewed	Nucleic acid binding
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14415	BXGT008010	Sodium/potassium-transporting ATPase subunit beta-2	482	reviewed	Transporter
P14679	BXGT008039	Tyrosinase	7299	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14784	BXGT008054	Interleukin-2 receptor subunit beta	3560	reviewed	Receptor
P15056	BXGT008075	Serine/threonine-protein kinase B-raf	673	reviewed	Kinase
P15151	BXGT008089	Poliovirus receptor	5817	reviewed
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15884	BXGT008166	Transcription factor 4	6925	reviewed	Transcription factor
P15907	BXGT008168	Beta-galactoside alpha-2,6-sialyltransferase 1	6480	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16278	BXGT008213	Beta-galactosidase	2720	reviewed	Enzyme
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P17861	BXGT008348	X-box-binding protein 1	7494	reviewed
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P18887	BXGT008437	DNA repair protein XRCC1	7515	reviewed
P19367	BXGT008476	Hexokinase-1	3098	reviewed	Kinase
P19544	BXGT008494	Wilms tumor protein	7490	reviewed	Nucleic acid binding
P20810	BXGT008602	Calpastatin	831	reviewed
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21359	BXGT008640	Neurofibromin	4763	reviewed	Enzyme modulator
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P22455	BXGT008772	Fibroblast growth factor receptor 4	2264	reviewed	Kinase
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P22897	BXGT008816	Macrophage mannose receptor 1	4360	reviewed
P23284	BXGT008845	Peptidyl-prolyl cis-trans isomerase B	5479	reviewed
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24941	BXGT009002	Cyclin-dependent kinase 2	1017	reviewed	Kinase
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P30086	BXGT009400	Phosphatidylethanolamine-binding protein 1	5037	reviewed	Enzyme modulator
P30279	BXGT009415	G1/S-specific cyclin-D2	894	reviewed	Enzyme modulator
P30281	BXGT009416	G1/S-specific cyclin-D3	896	reviewed	Enzyme modulator
P30291	BXGT009417	Wee1-like protein kinase	7465	reviewed	Kinase
P30411	BXGT009424	B2 bradykinin receptor	624	reviewed	G-protein coupled receptor
P30536	BXGT009435	Translocator protein	706	reviewed
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P30989	BXGT009492	Neurotensin receptor type 1	4923	reviewed	G-protein coupled receptor
P31260	BXGT009519	Homeobox protein Hox-A10	3206	reviewed
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31751	BXGT009576	RAC-beta serine/threonine-protein kinase	208	reviewed	Kinase
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P32321	BXGT009623	Deoxycytidylate deaminase	1635	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P34949	BXGT009775	Mannose-6-phosphate isomerase	4351	reviewed	Enzyme
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35414	BXGT009829	Apelin receptor	187	reviewed	G-protein coupled receptor
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36551	BXGT009927	Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial	1371	reviewed	Enzyme
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P37802	BXGT010013	Transgelin-2	8407	reviewed	Cellular structure
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P43246	BXGT010371	DNA mismatch repair protein Msh2	4436	reviewed	Nucleic acid binding
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46527	BXGT010525	Cyclin-dependent kinase inhibitor 1B	1027	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P47895	BXGT010593	Aldehyde dehydrogenase family 1 member A3	220	reviewed	Enzyme
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P48549	BXGT010644	G protein-activated inward rectifier potassium channel 1	3760	reviewed	Ion channel
P48735	BXGT010657	Isocitrate dehydrogenase [NADP], mitochondrial	3418	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49023	BXGT010672	Paxillin	5829	reviewed	Cellular structure
P49792	BXGT010743	E3 SUMO-protein ligase RanBP2	5903	reviewed	Enzyme modulator
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50053	BXGT010769	Ketohexokinase	3795	reviewed	Kinase
P50281	BXGT010788	Matrix metalloproteinase-14	4323	reviewed	Enzyme
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P50613	BXGT010815	Cyclin-dependent kinase 7	1022	reviewed	Kinase
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51790	BXGT010890	H(+)/Cl(-) exchange transporter 3	1182	reviewed	Ion channel
P51795	BXGT010891	H(+)/Cl(-) exchange transporter 5	1184	reviewed	Ion channel
P51955	BXGT010908	Serine/threonine-protein kinase Nek2	4751	reviewed	Kinase
P52701	BXGT010943	DNA mismatch repair protein Msh6	2956	reviewed	Nucleic acid binding
P52789	BXGT010954	Hexokinase-2	3099	reviewed	Kinase
P53350	BXGT010984	Serine/threonine-protein kinase PLK1	5347	reviewed	Kinase
P54760	BXGT011075	Ephrin type-B receptor 4	2050	reviewed	Kinase
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55085	BXGT011104	Proteinase-activated receptor 2	2150	reviewed	G-protein coupled receptor
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55212	BXGT011112	Caspase-6	839	reviewed	Enzyme
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P60953	BXGT011342	Cell division control protein 42 homolog	998	reviewed	Enzyme modulator
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P61088	BXGT011358	Ubiquitin-conjugating enzyme E2 N	7334	reviewed
P61587	BXGT011376	Rho-related GTP-binding protein RhoE	390	reviewed	Enzyme modulator
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78310	BXGT011830	Coxsackievirus and adenovirus receptor	1525	reviewed
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P84022	BXGT012027	Mothers against decapentaplegic homolog 3	4088	reviewed	Transcription factor
P84243	BXGT012052	Histone H3.3	3021	reviewed
P98170	BXGT012231	E3 ubiquitin-protein ligase XIAP	331	reviewed	Enzyme modulator
Q00534	BXGT012533	Cyclin-dependent kinase 6	1021	reviewed	Kinase
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01650	BXGT012603	Large neutral amino acids transporter small subunit 1	8140	reviewed	Transporter
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q02241	BXGT012644	Kinesin-like protein KIF23	9493	reviewed	Cellular structure
Q02763	BXGT012667	Angiopoietin-1 receptor	7010	reviewed	Kinase
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q04637	BXGT012771	Eukaryotic translation initiation factor 4 gamma 1	1981	reviewed	Nucleic acid binding
Q04721	BXGT012777	Neurogenic locus notch homolog protein 2	4853	reviewed
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q08050	BXGT012958	Forkhead box protein M1	2305	reviewed
Q08493	BXGT012987	cAMP-specific 3',5'-cyclic phosphodiesterase 4C	5143	reviewed
Q10471	BXGT013201	Polypeptide N-acetylgalactosaminyltransferase 2	2590	reviewed	Enzyme
Q12931	BXGT013282	Heat shock protein 75 kDa, mitochondrial	10131	reviewed	Chaperone
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13255	BXGT013332	Metabotropic glutamate receptor 1	2911	reviewed	G-protein coupled receptor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13427	BXGT013354	Peptidyl-prolyl cis-trans isomerase G	9360	reviewed
Q13464	BXGT013357	Rho-associated protein kinase 1	6093	reviewed	Kinase
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14164	BXGT013451	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	9641	reviewed	Kinase
Q14240	BXGT013458	Eukaryotic initiation factor 4A-II	1974	reviewed
Q14289	BXGT013459	Protein-tyrosine kinase 2-beta	2185	reviewed	Kinase
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14627	BXGT013492	Interleukin-13 receptor subunit alpha-2	3598	reviewed	Signaling
Q14680	BXGT013499	Maternal embryonic leucine zipper kinase	9833	reviewed	Kinase
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q14832	BXGT013507	Metabotropic glutamate receptor 3	2913	reviewed	G-protein coupled receptor
Q14833	BXGT013508	Metabotropic glutamate receptor 4	2914	reviewed	G-protein coupled receptor
Q14994	BXGT013519	Nuclear receptor subfamily 1 group I member 3	9970	reviewed	Nuclear receptor
Q15022	BXGT013523	Polycomb protein SUZ12	23512	reviewed	Nucleic acid binding
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15274	BXGT013556	Nicotinate-nucleotide pyrophosphorylase [carboxylating]	23475	reviewed
Q15366	BXGT013559	Poly(rC)-binding protein 2	5094	reviewed	Enzyme
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15562	BXGT013579	Transcriptional enhancer factor TEF-4	8463	reviewed	Transcription factor
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q15758	BXGT013594	Neutral amino acid transporter B(0)	6510	reviewed	Transporter
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16790	BXGT013670	Carbonic anhydrase 9	768	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q7KZF4	BXGT016989	Staphylococcal nuclease domain-containing protein 1	27044	reviewed	Transcription factor
Q86U44	BXGT017610	N6-adenosine-methyltransferase catalytic subunit	56339	reviewed
Q8IUQ4	BXGT018336	E3 ubiquitin-protein ligase SIAH1	6477	reviewed
Q8IXJ6	BXGT018362	NAD-dependent protein deacetylase sirtuin-2	22933	reviewed	Epigenetic regulator
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8NEM0	BXGT018555	Microcephalin	79648	reviewed	Nucleic acid binding
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92876	BXGT019388	Kallikrein-6	5653	reviewed	Enzyme
Q92934	BXGT019396	Bcl2-associated agonist of cell death	572	reviewed
Q92945	BXGT019397	Far upstream element-binding protein 2	8570	reviewed	Enzyme
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96F46	BXGT019656	Interleukin-17 receptor A	23765	reviewed
Q96GD4	BXGT019667	Aurora kinase B	9212	reviewed	Kinase
Q96JA1	BXGT019681	Leucine-rich repeats and immunoglobulin-like domains protein 1	26018	reviewed	Receptor
Q99624	BXGT019942	Sodium-coupled neutral amino acid transporter 3	10991	reviewed	Transporter
Q99814	BXGT019965	Endothelial PAS domain-containing protein 1	2034	reviewed	Transcription factor
Q99933	BXGT019976	BAG family molecular chaperone regulator 1	573	reviewed
Q9BUZ4	BXGT020139	TNF receptor-associated factor 4	9618	reviewed	Signaling
Q9BXH1	BXGT020167	Bcl-2-binding component 3	27113	reviewed
Q9BYW2	BXGT020192	Histone-lysine N-methyltransferase SETD2	29072	reviewed	Epigenetic regulator
Q9H2G2	BXGT020452	STE20-like serine/threonine-protein kinase	9748	reviewed	Kinase
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H7B4	BXGT020490	Histone-lysine N-methyltransferase SMYD3	64754	reviewed	Epigenetic regulator
Q9HD26	BXGT020540	Golgi-associated PDZ and coiled-coil motif-containing protein	57120	reviewed
Q9NR28	BXGT021178	Diablo homolog, mitochondrial	56616	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRM7	BXGT021190	Serine/threonine-protein kinase LATS2	26524	reviewed	Kinase
Q9NUX5	BXGT021220	Protection of telomeres protein 1	25913	reviewed	Nucleic acid binding
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P2K8	BXGT021302	eIF-2-alpha kinase GCN2	440275	reviewed
Q9UBG0	BXGT021654	C-type mannose receptor 2	9902	reviewed
Q9UER7	BXGT021672	Death domain-associated protein 6	1616	reviewed
Q9UHX3	BXGT021708	Adhesion G protein-coupled receptor E2	30817	reviewed	G-protein coupled receptor
Q9UHY7	BXGT021709	Enolase-phosphatase E1	58478	reviewed	Enzyme
Q9UI32	BXGT021711	Glutaminase liver isoform, mitochondrial	27165	reviewed	Enzyme
Q9UJ41	BXGT021723	Rab5 GDP/GTP exchange factor	27342	reviewed	Enzyme modulator
Q9UM47	BXGT021772	Neurogenic locus notch homolog protein 3	4854	reviewed
Q9Y243	BXGT022214	RAC-gamma serine/threonine-protein kinase	10000	reviewed	Kinase
Q9Y286	BXGT022225	Sialic acid-binding Ig-like lectin 7	27036	reviewed	Receptor
Q9Y2D1	BXGT022230	Cyclic AMP-dependent transcription factor ATF-5	22809	reviewed
Q9Y2Q3	BXGT022242	Glutathione S-transferase kappa 1	373156	reviewed
Q9H2H9	BXGT022646	Sodium-coupled neutral amino acid transporter 1	81539	reviewed	Transporter
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P43146	BXGT022852	Netrin receptor DCC	1630	reviewed
O60936	BXGT022857	Nucleolar protein 3	8996	reviewed
P19235	BXGT022895	Erythropoietin receptor	2057	reviewed	Receptor
P35240	BXGT022927	Merlin	4771	reviewed
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q13007	BXGT023883	Interleukin-24	11009	reviewed
O60232	BXGT024169	Protein ZNRD2	10534	reviewed
P16104	BXGT024571	Histone H2AX	3014	reviewed	Nucleic acid binding
Q16763	BXGT025332	Ubiquitin-conjugating enzyme E2 S	27338	reviewed
Q9GZV5	BXGT025439	WW domain-containing transcription regulator protein 1	25937	reviewed	Enzyme modulator
Q9UGM3	BXGT025543	Deleted in malignant brain tumors 1 protein	1755	reviewed	Enzyme
Q9BY76	BXGT025687	Angiopoietin-related protein 4	51129	reviewed	Signaling
Q9BVC4	BXGT026090	Target of rapamycin complex subunit LST8	64223	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
V9HWB9	BXGT026149	L-lactate dehydrogenase	3939	unreviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}