protein

Showing entry for Dual specificity testis-specific protein kinase 1

　　　　　　　　　　　　

General Target Information
BXGT Id	BXGT013580
Protein Name	Dual specificity testis-specific protein kinase 1
Uniport Id	Q15569
Gene	TESK1
Gene Id	7016
Domain	Pkinase_Tyr
Pfam	PF07714
Organism	Homo sapiens (Human)

Target protein affiliated biological pathways

KEGG

Class	Subclass	KEGG Id	Pathway Name

Gene Ontology

GO Type	GO Id	Gene Ontology
Biological Process	GO:0030036	actin cytoskeleton organization
Biological Process	GO:0031953	negative regulation of protein autophosphorylation
Biological Process	GO:0071901	negative regulation of protein serine/threonine kinase activity
Biological Process	GO:0051496	positive regulation of stress fiber assembly
Biological Process	GO:0032880	regulation of protein localization
Biological Process	GO:0007283	spermatogenesis
molecular function	GO:0005524	ATP binding
molecular function	GO:0046872	metal ion binding
molecular function	GO:0008022	protein C-terminus binding
molecular function	GO:0019901	protein kinase binding
molecular function	GO:0004712	protein serine/threonine/tyrosine kinase activity
molecular function	GO:0004674	protein serine/threonine kinase activity
molecular function	GO:0004713	protein tyrosine kinase activity
cellular component	GO:0005737	cytoplasm
cellular component	GO:0031410	cytoplasmic vesicle
cellular component	GO:0005829	cytosol
cellular component	GO:0005634	nucleus

Reactome

Pathway Id	Pathway Name
R-HSA-1500931	Cell-Cell communication
R-HSA-446353	Cell-extracellular matrix interactions
R-HSA-446388	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
R-HSA-446728	Cell junction organization

Target protein-related diseases

Disease

CUI Id	BXGD Id	Disease Name	Disease Class
C0006142	BXGD000374	Malignant neoplasm of breast	Neoplasms; Skin and Connective Tissue Diseases
C0022104	BXGD001529	Irritable Bowel Syndrome	Digestive System Diseases
C0432306	BXGD008770	Ichthyosis Bullosa of Siemens	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases

Target protein-related compounds

Compounds

BXGC Id	Compound Name	Strcuture	Molecular Weight
BXGC0042376	Picropodophyllotoxin		414.13
BXGC0045254	Sb-202190		331.11
BXGC0047692	Gefitinib		446.15

The target protein-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compound^{? Number of compound in food, higher numbers indicate the food are more associated with the protein}