Showing entry for Dual specificity protein phosphatase 6


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016113
Protein NameDual specificity protein phosphatase 6
Uniport IdQ64346
GeneDusp6
Gene Id116663
DomainDSPc; Rhodanese
Pfam PF00782   PF00581  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030154 cell differentiation
Biological Process GO:0000188 inactivation of MAPK activity
Biological Process GO:0070373 negative regulation of ERK1 and ERK2 cascade
Biological Process GO:0001933 negative regulation of protein phosphorylation
Biological Process GO:0035970 peptidyl-threonine dephosphorylation
Biological Process GO:0035335 peptidyl-tyrosine dephosphorylation
Biological Process GO:0043065 positive regulation of apoptotic process
Biological Process GO:0010942 positive regulation of cell death
Biological Process GO:0006470 protein dephosphorylation
Biological Process GO:0060420 regulation of heart growth
Biological Process GO:0042493 response to drug
Biological Process GO:0070848 response to growth factor
Biological Process GO:0051409 response to nitrosative stress
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010033 response to organic substance
molecular function GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity
molecular function GO:0051019 mitogen-activated protein kinase binding
molecular function GO:0004721 phosphoprotein phosphatase activity
molecular function GO:0008138 protein tyrosine/serine/threonine phosphatase activity
molecular function GO:0008330 protein tyrosine/threonine phosphatase activity
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000116 1,4-Naphtoquinone 158.15
BXGC0001991 Juglone 174.15
BXGC0003456 1,4-Benzoquinone 108.09
BXGC0006193 Ellagic acid 302.19
BXGC0020344 Icosa-5,8,11,14-Tetraynoic Acid 296.18
BXGC0020680 Mandelic Acid 152.05
BXGC0022865 (2S)-2-Hydroxy-2-Phenylacetic Acid 152.05
BXGC0025204 Anthraquinone 208.05
BXGC0027720 (r)-mandelic acid 152.05
BXGC0044200 Menadione 172.05
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein