Showing entry for Transient receptor potential cation channel subfamily A member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016509
Protein NameTransient receptor potential cation channel subfamily A member 1
Uniport IdQ6RI86
GeneTrpa1
Gene Id312896
DomainAnk_2; Ion_trans
Pfam PF12796   PF00520  
OrganismRattus norvegicus (Rat)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0071313 cellular response to caffeine
Biological Process GO:0071244 cellular response to carbon dioxide
Biological Process GO:0070417 cellular response to cold
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0050968 detection of chemical stimulus involved in sensory perception of pain
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:1903793 positive regulation of anion transport
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:1904058 positive regulation of sensory perception of pain
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:1903522 regulation of blood circulation
Biological Process GO:0098908 regulation of neuronal action potential
Biological Process GO:0009409 response to cold
Biological Process GO:0042493 response to drug
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010033 response to organic substance
Biological Process GO:0048265 response to pain
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0050955 thermoception
Biological Process GO:0014832 urinary bladder smooth muscle contraction
molecular function GO:0005262 calcium channel activity
molecular function GO:0015278 calcium-release channel activity
molecular function GO:0015267 channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005216 ion channel activity
molecular function GO:1990760 osmolarity-sensing cation channel activity
molecular function GO:0097604 temperature-gated cation channel activity
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0032421 stereocilium bundle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000664 Maxepa 314.46
BXGC0000694 (S)-[6]-Gingerol 294.39
BXGC0000929 4-Hydroxy-2E-nonenal 156.22
BXGC0001767 (E)-Resveratrol 228.25
BXGC0002677 Sulfur 32.07
BXGC0002780 (E)-Butylidene phthalide 188.23
BXGC0003372 Photoantheole 240.3
BXGC0003949 Thymunic acid 150.22
BXGC0004058 [8]-Shogaol 276.37
BXGC0006092 3-Isothiocyanato-1-propene 99.15
BXGC0006095 (??)-Citronellyl acetate 198.31
BXGC0006982 Geraniol 154.25
BXGC0006984 Geranyl acetate 196.29
BXGC0007011 (R)-Perillaldehyde 150.22
BXGC0007134 Perilla ketone 166.22
BXGC0007521 Citronellol 156.27
BXGC0007824 Nerol 154.25
BXGC0021248 Shogaol 276.17
BXGC0021403 Cannabinol 310.19
BXGC0023497 Pterostilbene 256.11
BXGC0026472 Cannabigerol 316.24
BXGC0028924 Cannabichromene 314.22
BXGC0034035 Capsaicin 305.2
BXGC0038936 Cannabidiol Acid 358.21
BXGC0039083 Pinosylvin 212.08
BXGC0040150 Cannabidiol 314.22
BXGC0042175 5-Hydroxy-1-(4-Hydroxyphenyl)Decan-3-One 264.17
BXGC0042963 3,5-O-Dimethylpinosylvin 240.12
BXGC0046562 Geranyl Acetate 196.15
BXGC0051357 Trismethoxyresveratrol 270.13
BXGC0053078 Pinosylvin Methyl Ether 226.1
BXGC0053902 Sesquicannabigerol 384.3
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein