Showing entry for Cytoplasmic FMR1-interacting protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT016995
Protein NameCytoplasmic FMR1-interacting protein 1
Uniport IdQ7L576
GeneCYFIP1
Gene Id23191
DomainDUF1394; FragX_IP
Pfam PF07159   PF05994  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03013 RNA transport
4. Cellular Processes 4.5 Cell motility hsa04810 Regulation of actin cytoskeleton
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048675 axon extension
Biological Process GO:0007411 axon guidance
Biological Process GO:0000902 cell morphogenesis
Biological Process GO:0030031 cell projection assembly
Biological Process GO:0032869 cellular response to insulin stimulus
Biological Process GO:0050890 cognition
Biological Process GO:0097484 dendrite extension
Biological Process GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis
Biological Process GO:0030032 lamellipodium assembly
Biological Process GO:0099563 modification of synaptic structure
Biological Process GO:1903422 negative regulation of synaptic vesicle recycling
Biological Process GO:0043312 neutrophil degranulation
Biological Process GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation
Biological Process GO:0045773 positive regulation of axon extension
Biological Process GO:1900006 positive regulation of dendrite development
Biological Process GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway
Biological Process GO:1900029 positive regulation of ruffle assembly
Biological Process GO:0016601 Rac protein signal transduction
Biological Process GO:0008360 regulation of cell shape
Biological Process GO:1905274 regulation of modification of postsynaptic actin cytoskeleton
Biological Process GO:0031641 regulation of myelination
Biological Process GO:0006417 regulation of translation
Biological Process GO:0051602 response to electrical stimulus
Biological Process GO:0031529 ruffle organization
Biological Process GO:0048010 vascular endothelial growth factor receptor signaling pathway
molecular function GO:0051015 actin filament binding
molecular function GO:0048365 Rac GTPase binding
molecular function GO:0000340 RNA 7-methylguanosine cap binding
cellular component GO:0044295 axonal growth cone
cellular component GO:0090724 central region of growth cone
cellular component GO:0005829 cytosol
cellular component GO:0044294 dendritic growth cone
cellular component GO:0043197 dendritic spine
cellular component GO:0060076 excitatory synapse
cellular component GO:0070062 extracellular exosome
cellular component GO:0005576 extracellular region
cellular component GO:0032433 filopodium tip
cellular component GO:0005925 focal adhesion
cellular component GO:0030027 lamellipodium
cellular component GO:0005845 mRNA cap binding complex
cellular component GO:0043025 neuronal cell body
cellular component GO:0043005 neuron projection
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0090725 peripheral region of growth cone
cellular component GO:0001726 ruffle
cellular component GO:0031209 SCAR complex
cellular component GO:0034774 secretory granule lumen
cellular component GO:0035580 specific granule lumen
cellular component GO:0045202 synapse
cellular component GO:0043195 terminal bouton
cellular component GO:1904724 tertiary granule lumen
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-1643685 Disease
R-HSA-168249 Innate Immune System
R-HSA-168249 Innate Immune System
R-HSA-168256 Immune System
R-HSA-168256 Immune System
R-HSA-194138 Signaling by VEGF
R-HSA-194315 Signaling by Rho GTPases
R-HSA-194315 Signaling by Rho GTPases
R-HSA-195258 RHO GTPase Effectors
R-HSA-195258 RHO GTPase Effectors
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029480 Fcgamma receptor (FCGR) dependent phagocytosis
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-5663205 Infectious disease
R-HSA-5663205 Infectious disease
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs
R-HSA-6798695 Neutrophil degranulation
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9658195 Leishmania infection
R-HSA-9658195 Leishmania infection
R-HSA-9664407 Parasite infection
R-HSA-9664407 Parasite infection
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664417 Leishmania phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
R-HSA-9664422 FCGR3A-mediated phagocytosis
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0006111 BXGD000369 Brain Diseases Nervous System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007682 BXGD000471 CNS disorder Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0014556 BXGD000932 Epilepsy, Temporal Lobe Nervous System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0023348 BXGD001636 Leprosy, Lepromatous Infections
C0023449 BXGD001650 Acute lymphocytic leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0023452 BXGD001651 Childhood Acute Lymphoblastic Leukemia Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0032897 BXGD002378 Prader-Willi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038454 BXGD002760 Cerebrovascular accident Nervous System Diseases; Cardiovascular Diseases
C0162635 BXGD003964 Angelman Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0427460 BXGD008616 Red cell distribution width determination
C0520947 BXGD009126 Clumsiness - motor delay Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0553723 BXGD009416 Squamous cell carcinoma of skin Neoplasms; Skin and Connective Tissue Diseases
C0600104 BXGD009690 Obsessive compulsive behavior Behavior and Behavior Mechanisms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0686619 BXGD009835 Secondary malignant neoplasm of lymph node Pathological Conditions, Signs and Symptoms; Neoplasms
C0751606 BXGD010523 Adult Acute Lymphocytic Leukemia
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1368683 BXGD012900 Epithelioma Neoplasms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1562908 BXGD013381 Leprosy, Paucibacillary Infections
C1860787 BXGD015997 DOWN SYNDROME CRITICAL REGION Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1961102 BXGD016673 Precursor Cell Lymphoblastic Leukemia Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C2931822 BXGD018068 Nasopharyngeal carcinoma Neoplasms; Stomatognathic Diseases; Otorhinolaryngologic Diseases
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein