Showing entry for Prader-Willi Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002378
Disease NamePrader-Willi Syndrome
Disease CUI IdC0032897
MeSH Codes C16   C18   C10  
Disease Class NameCongenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:630   DOID:7   DOID:225   DOID:150  
Disease Ontology Class Namegenetic disease; disease of anatomical entity; syndrome; disease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
F7VJQ1 BXGT003310 Alternative prion protein 5621 reviewed
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14578 BXGT004072 Citron Rho-interacting kinase 11113 reviewed Kinase
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 5170 reviewed Kinase
O43612 BXGT004605 Orexin 3060 reviewed
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
P00156 BXGT005469 Cytochrome b 4519 reviewed
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02818 BXGT005969 Osteocalcin 632 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04156 BXGT006156 Major prion protein 5621 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P19113 BXGT008458 Histidine decarboxylase 3067 reviewed
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P22736 BXGT008800 Nuclear receptor subfamily 4 group A member 1 3164 reviewed Nuclear receptor
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31644 BXGT009557 Gamma-aminobutyric acid receptor subunit alpha-5 2558 reviewed Ion channel
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49146 BXGT010681 Neuropeptide Y receptor type 2 4887 reviewed G-protein coupled receptor
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P54762 BXGT011076 Ephrin type-B receptor 1 2047 reviewed Kinase
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q13535 BXGT013370 Serine/threonine-protein kinase ATR 545 reviewed Kinase
Q14118 BXGT013444 Dystroglycan 1605 reviewed Receptor
Q15047 BXGT013528 Histone-lysine N-methyltransferase SETDB1 9869 reviewed
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q7L576 BXGT016995 Cytoplasmic FMR1-interacting protein 1 23191 reviewed Enzyme modulator
Q86V24 BXGT017615 Adiponectin receptor protein 2 79602 reviewed Receptor
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 10919 reviewed Epigenetic regulator
Q96MG7 BXGT019696 Non-structural maintenance of chromosomes element 3 homolog 56160 reviewed Cell adhesion
Q99928 BXGT019975 Gamma-aminobutyric acid receptor subunit gamma-3 2567 reviewed Ion channel
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UNN8 BXGT021791 Endothelial protein C receptor 10544 reviewed Enzyme modulator
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
P29590 BXGT024350 Protein PML 5371 reviewed
Q9BYE2 BXGT024631 Transmembrane protease serine 13 84000 reviewed Enzyme
Q96A54 BXGT024681 Adiponectin receptor protein 1 51094 reviewed Receptor
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
Q86SQ9 BXGT025875 Dehydrodolichyl diphosphate synthase complex subunit DHDDS 79947 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease