Showing entry for Organic solute transporter subunit alpha


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017613
Protein NameOrganic solute transporter subunit alpha
Uniport IdQ86UW1
GeneSLC51A
Gene Id200931
DomainSolute_trans_a
Pfam PF03619  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04976 Bile secretion
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0015721 bile acid and bile salt transport
Biological Process GO:0032782 bile acid secretion
molecular function GO:0015125 bile acid transmembrane transporter activity
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
cellular component GO:0032991 protein-containing complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0008312 BXGD000527 Primary biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0008370 BXGD000534 Cholestasis Digestive System Diseases
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0023892 BXGD001715 Biliary cirrhosis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0029456 BXGD002157 Osteoporosis Nutritional and Metabolic Diseases; Musculoskeletal Diseases
C0238065 BXGD004869 Secondary Biliary Cholangitis Pathological Conditions, Signs and Symptoms; Digestive System Diseases
C0342257 BXGD007447 Complications of Diabetes Mellitus Endocrine System Diseases
C1837073 BXGD014191 Spondylometaphyseal Dysplasia with Cone-Rod Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases; Musculoskeletal Diseases
C3241937 BXGD018578 Nonalcoholic Steatohepatitis Digestive System Diseases
C4551595 BXGD023367 Biliary Cirrhosis, Primary, 1 Pathological Conditions, Signs and Symptoms; Digestive System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0022544 Digoxin 780.43
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein