adisease

Showing entry for Biliary cirrhosis

General Disease Information
BXGD Id	BXGD001715
Disease Name	Biliary cirrhosis
Disease CUI Id	C0023892
MeSH Codes	C23 C06
Disease Class Name	Pathological Conditions, Signs and Symptoms; Digestive System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0025031
Human Phenotype Ontology Term	Abnormality of the digestive system
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00330	BXGT003910	Pyruvate dehydrogenase protein X component, mitochondrial	8050	reviewed	Enzyme
O15439	BXGT004169	Multidrug resistance-associated protein 4	10257	reviewed	Transporter
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O75676	BXGT005144	Ribosomal protein S6 kinase alpha-4	8986	reviewed	Kinase
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O95150	BXGT005351	Tumor necrosis factor ligand superfamily member 15	9966	reviewed	Signaling
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P05187	BXGT006339	Alkaline phosphatase, placental type	250	reviewed	Enzyme
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13569	BXGT007923	Cystic fibrosis transmembrane conductance regulator	1080	reviewed	Ion channel
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16871	BXGT008269	Interleukin-7 receptor subunit alpha	3575	reviewed	Receptor
P17174	BXGT008289	Aspartate aminotransferase, cytoplasmic	2805	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P21439	BXGT008649	Phosphatidylcholine translocator ABCB4	5244	reviewed	Transporter
P22749	BXGT008803	Granulysin	10578	reviewed
P23443	BXGT008866	Ribosomal protein S6 kinase beta-1	6198	reviewed	Kinase
P28300	BXGT009243	Protein-lysine 6-oxidase	4015	reviewed
P29460	BXGT009348	Interleukin-12 subunit beta	3593	reviewed	Signaling
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29597	BXGT009367	Non-receptor tyrosine-protein kinase TYK2	7297	reviewed	Kinase
P32302	BXGT009619	C-X-C chemokine receptor type 5	643	reviewed	G-protein coupled receptor
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38936	BXGT010074	Cyclin-dependent kinase inhibitor 1	1026	reviewed
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P50591	BXGT010814	Tumor necrosis factor ligand superfamily member 10	8743	reviewed	Signaling
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P81172	BXGT011935	Hepcidin	57817	reviewed
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q7Z494	BXGT017254	Nephrocystin-3	27031	reviewed
Q86UW1	BXGT017613	Organic solute transporter subunit alpha	200931	reviewed	Transporter
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8WWM9	BXGT019001	Cytoglobin	114757	reviewed
Q92887	BXGT019389	Canalicular multispecific organic anion transporter 1	1244	reviewed	Transporter
Q96QV1	BXGT019722	Hedgehog-interacting protein	64399	reviewed
Q99558	BXGT019934	Mitogen-activated protein kinase kinase kinase 14	9020	reviewed	Kinase
Q9BYF1	BXGT020186	Angiotensin-converting enzyme 2	59272	reviewed	Enzyme
Q9NYB5	BXGT021255	Solute carrier organic anion transporter family member 1C1	53919	reviewed	Transporter
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	9429	reviewed	Transporter
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y4K0	BXGT022280	Lysyl oxidase homolog 2	4017	reviewed
Q9Y5L0	BXGT022296	Transportin-3	23534	reviewed	Transporter

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}