Showing entry for Transient receptor potential cation channel subfamily A member 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT017916
Protein NameTransient receptor potential cation channel subfamily A member 1
Uniport IdQ8BLA8
GeneTrpa1
Gene Id277328
DomainAnk_2; Ion_trans
Pfam PF12796   PF00520  
OrganismMus musculus (Mouse)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0097553 calcium ion transmembrane import into cytosol
Biological Process GO:0070588 calcium ion transmembrane transport
Biological Process GO:0006816 calcium ion transport
Biological Process GO:0007166 cell surface receptor signaling pathway
Biological Process GO:0071244 cellular response to carbon dioxide
Biological Process GO:0070417 cellular response to cold
Biological Process GO:0034605 cellular response to heat
Biological Process GO:0050968 detection of chemical stimulus involved in sensory perception of pain
Biological Process GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
Biological Process GO:1903793 positive regulation of anion transport
Biological Process GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
Biological Process GO:1904058 positive regulation of sensory perception of pain
Biological Process GO:0051289 protein homotetramerization
Biological Process GO:1903522 regulation of blood circulation
Biological Process GO:0098908 regulation of neuronal action potential
Biological Process GO:0009409 response to cold
Biological Process GO:0042493 response to drug
Biological Process GO:0042542 response to hydrogen peroxide
Biological Process GO:0014070 response to organic cyclic compound
Biological Process GO:0010033 response to organic substance
Biological Process GO:0048265 response to pain
Biological Process GO:0019233 sensory perception of pain
Biological Process GO:0050955 thermoception
Biological Process GO:0014832 urinary bladder smooth muscle contraction
molecular function GO:0005262 calcium channel activity
molecular function GO:0015278 calcium-release channel activity
molecular function GO:0015267 channel activity
molecular function GO:0042802 identical protein binding
molecular function GO:0005216 ion channel activity
molecular function GO:1990760 osmolarity-sensing cation channel activity
molecular function GO:0097604 temperature-gated cation channel activity
molecular function GO:0005245 voltage-gated calcium channel activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0030424 axon
cellular component GO:0016021 integral component of membrane
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0032421 stereocilium bundle
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002599 2-Propene-1-sulfinothiocic-acids 2-propenyl ester 162.27
BXGC0004587 (E)-3-Phenyl-2-propenal 132.16
BXGC0006092 3-Isothiocyanato-1-propene 99.15
BXGC0007525 (-)-Menthol 156.27
BXGC0007528 p-Menthan-3-ol 156.27
BXGC0024988 Nifedipine 346.12
BXGC0043126 Nicardipine 479.21
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein