Showing entry for Nicardipine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0043126
Compound NameNicardipine
Structure
FormulaC26H29N3O6
InchiKeyZBBHBTPTTSWHBA-UHFFFAOYSA-N
SMILESCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1)N(=O)=O)C(=O)OCCN(Cc1ccccc1)C)C
InchiInChI=1S/C26H29N3O6/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19/h5-12,15,24,27H,13-14,16H2,1-4H3
IUPAC5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Molecular Weight479.21
Pubchem Id4474
Chembl IdCHEMBL1484
Targets of Information Source
DrugBank DB00622
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C approved; investigational inhibitor
Q08289 BXGT012979 Voltage-dependent L-type calcium channel subunit beta-2 reviewed Ion channel CACNB2 approved; investigational inhibitor
P54289 BXGT011040 Voltage-dependent calcium channel subunit alpha-2/delta-1 reviewed Ion channel CACNA2D1 approved; investigational inhibitor
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D reviewed Ion channel CACNA1D approved; investigational inhibitor
P54750 BXGT011072 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A reviewed - PDE1A approved; investigational inhibitor
Q01064 BXGT012564 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B reviewed - PDE1B approved; investigational inhibitor
P35348 BXGT009814 Alpha-1A adrenergic receptor reviewed G-protein coupled receptor ADRA1A approved; investigational antagonist
P35368 BXGT009822 Alpha-1B adrenergic receptor reviewed G-protein coupled receptor ADRA1B approved; investigational antagonist
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D approved; investigational antagonist
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 approved; investigational antagonist
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 approved; investigational antagonist
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 approved; investigational antagonist
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 approved; investigational antagonist
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 approved; investigational antagonist
P0DP23 BXGT007520 Calmodulin-1 reviewed - CALM1 approved; investigational other/unknown
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50101815
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C - 9600 - -
reviewed BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C - 250 - -
reviewed BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C - 24100 - -
reviewed BXGT009707 Cytochrome P450 2C19 reviewed CYP2C19 - 3300 - -
reviewed BXGT007595 Cytochrome P450 2D6 reviewed CYP2D6 - 1590 - -
reviewed BXGT007738 Cytochrome P450 2C9 reviewed CYP2C9 - 378 - -
reviewed BXGT007592 Cytochrome P450 2C8 reviewed CYP2C8 - 1560 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - >30000 - -
reviewed BXGT007595 Cytochrome P450 2D6 reviewed CYP2D6 - 1780 - -
reviewed BXGT009707 Cytochrome P450 2C19 reviewed CYP2C19 - 560 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - 380 - -
reviewed BXGT010867 Cytochrome P450 2J2 reviewed CYP2J2 - 1690 - -
reviewed BXGT007738 Cytochrome P450 2C9 reviewed CYP2C9 - 660 - -
reviewed BXGT008160 Alpha-1B adrenergic receptor reviewed Adra1b - 3600 - -
reviewed BXGT008160 Alpha-1B adrenergic receptor reviewed Adra1b - >10000 - -
reviewed BXGT008818 Alpha-2A adrenergic receptor reviewed Adra2a - 1400 - -
reviewed BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A - >10000 - -
CHEMBL CHEMBL1484
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 23280 nM
P00811 BXGT005666 Beta-lactamase reviewed - ampC Inhibition '=' 32 %
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '<' 10000 nM
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C IC50 '=' 24100 nM
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki '=' 3250 nM
P28647 BXGT009282 Adenosine receptor A3 reviewed - Adora3 Inhibition '=' 27 %
P00811 BXGT005666 Beta-lactamase reviewed - ampC IC50 '=' 20000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Activity - - -
Q8R0V5 BXGT018678 Indoleamine 2,3-dioxygenase 2 reviewed - Ido2 Inhibition '>=' 55 %
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 '=' 560 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 '=' 13300 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_ATPase activity '=' 5 -
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 19952 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 58047 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 44668 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 22387 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 661 nm/s
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 4786 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 5600 nM
P28647 BXGT009282 Adenosine receptor A3 reviewed - Adora3 Ki '=' 11000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 56234 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 7079 nM
P00346 BXGT005508 Malate dehydrogenase, mitochondrial reviewed - MDH2 IC50 '=' 49 -
P06795 BXGT006507 ATP-dependent translocase ABCB1 reviewed - Abcb1b IC50 '=' 8000 nM
P28647 BXGT009282 Adenosine receptor A3 reviewed - Adora3 Ratio '=' 1 -
P25099 BXGT009016 Adenosine receptor A1 reviewed - Adora1 Ratio '=' 1 -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 1835 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Papp '=' 614 nm/s
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 12589 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 25118 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 % maximum response '=' 102 %
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 5128 nM
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 37685 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 33587 nM
O54698 BXGT004728 Equilibrative nucleoside transporter 1 reviewed - Slc29a1 Ki '=' 5360 nM
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 28183 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 2 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 2300 nM
P21447 BXGT008651 ATP-dependent translocase ABCB1 reviewed - Abcb1a IC50 '=' 2500 nM
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition '=' 50 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 13335 nM
P15917 BXGT008169 Lethal factor reviewed - lef FC '=' 5 -
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 35481 nM
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 '>' 10000 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d IC50 '>' 10000 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 '>' 10000 nM
P25094 BXGT009014 Peripheral myelin protein 22 reviewed - Pmp22 Potency - 5102 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 17500 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity - - -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 18 nM/mg*min
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition '=' 0 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 9441 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 950 nM
P00811 BXGT005666 Beta-lactamase reviewed - ampC IC50 '>' 50 -
P00766 BXGT005647 Chymotrypsinogen A reviewed - IC50 '=' 175000 nM
P40925 BXGT010206 Malate dehydrogenase, cytoplasmic reviewed Enzyme MDH1 IC50 '=' 50000 nM
O35433 BXGT004528 Transient receptor potential cation channel subfamily V member 1 reviewed - Trpv1 Activity - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 14581 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 7943 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '=' 380 nM
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition '=' 61 %
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 reviewed Ion channel TRPV1 Activity - - -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 1995 nM
Q83TT7 BXGT017514 AmpC unreviewed - ampC Activity - - -
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 18492 nM
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C IC50 '=' 9600 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Inhibition '=' 100 %
P30543 BXGT009437 Adenosine receptor A2a reviewed - Adora2a Ki '=' 63800 nM
P22909 BXGT008818 Alpha-2A adrenergic receptor reviewed - Adra2a IC50 '=' 1400 nM
P19328 BXGT008473 Alpha-2B adrenergic receptor reviewed - Adra2b IC50 '=' 1400 nM
P22086 BXGT008728 Alpha-2C adrenergic receptor reviewed - Adra2c IC50 '=' 1400 nM
P27732 BXGT009204 Voltage-dependent L-type calcium channel subunit alpha-1D reviewed - Cacna1d Ki '=' 0 nM
Q02485 BXGT012654 Voltage-dependent L-type calcium channel subunit alpha-1S reviewed - Cacna1s Ki '=' 0 nM
P22002 BXGT008717 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed - Cacna1c Ki '=' 0 nM
P00766 BXGT005647 Chymotrypsinogen A reviewed - IC50 '=' 3 -
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 29934 nM
P05364 BXGT006351 Beta-lactamase reviewed - ampC IC50 '>' 50 -
P00766 BXGT005647 Chymotrypsinogen A reviewed - IC50 '=' 2 -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 6600 nM
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 Activity - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 17229 nM
O15439 BXGT004169 Multidrug resistance-associated protein 4 reviewed Transporter ABCC4 IC50 '=' 88000 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 7870 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 19952 nM
P00811 BXGT005666 Beta-lactamase reviewed - ampC Inhibition '=' 33 %
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 59 %
Q8BLA8 BXGT017916 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 EC50 '=' 500 nM
P00811 BXGT005666 Beta-lactamase reviewed - ampC Inhibition '=' 81 %
P27732 BXGT009204 Voltage-dependent L-type calcium channel subunit alpha-1D reviewed - Cacna1d IC50 '=' 2 nM
Q02485 BXGT012654 Voltage-dependent L-type calcium channel subunit alpha-1S reviewed - Cacna1s IC50 '=' 2 nM
P22002 BXGT008717 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed - Cacna1c IC50 '=' 2 nM
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 '>' 10000 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 '>' 10000 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 '>' 10000 nM
P25099 BXGT009016 Adenosine receptor A1 reviewed - Adora1 Ki '=' 19600 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 '=' 378 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Activity '=' 100 %
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '>' 25800 nM
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 '=' 3600 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d IC50 '=' 3600 nM
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 '=' 3600 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki '=' 280 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 Ratio_Papp '=' 1 -
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition '=' 88 %
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 79432 nM
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 '=' 3300 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 23099 nM
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition - - -
P28647 BXGT009282 Adenosine receptor A3 reviewed - Adora3 Inhibition '<' 7 %
P28647 BXGT009282 Adenosine receptor A3 reviewed - Adora3 Ratio '=' 5 -
P30543 BXGT009437 Adenosine receptor A2a reviewed - Adora2a Ratio '=' 5 -
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 115820 nM
P00346 BXGT005508 Malate dehydrogenase, mitochondrial reviewed - MDH2 IC50 - - -
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 reviewed - PIN1 Potency - 6 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 3200 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 8912 nM
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 26121 nM
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 35481 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 4540 nM
O94956 BXGT005343 Solute carrier organic anion transporter family member 2B1 reviewed Transporter SLCO2B1 Inhibition '=' 31 %
O94782 BXGT005332 Ubiquitin carboxyl-terminal hydrolase 1 reviewed Enzyme USP1 Potency - 28183 nM
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C reviewed Ion channel CACNA1C IC50 '=' 250 nM
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 10 %
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 31238 nM
P05453 BXGT006363 Eukaryotic peptide chain release factor GTP-binding subunit reviewed - SUP35 Inhibition '=' 55 %
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 65 %
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '=' 420 nM
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 reviewed Transporter ABCG2 IC50 '=' 16595 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 7100 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 IC50 '=' 133000 nM
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA FC '=' 16 -
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 16353 nM
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 4228 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 '=' 1590 nM
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 Activity '=' 5 %
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 Activity '=' 8 %
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 '=' 1780 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 11700 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 14600 nM
P10632 BXGT007592 Cytochrome P450 2C8 reviewed - CYP2C8 IC50 '=' 1560 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 35481 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 '>' 30000 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB PPB '=' 95 %
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Activity - - -
P51589 BXGT010867 Cytochrome P450 2J2 reviewed - CYP2J2 IC50 '=' 1690 nM
O95342 BXGT005373 Bile salt export pump reviewed Transporter ABCB11 IC50 '=' 7900 nM
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA Inhibition '=' 77 %
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA IC50 '=' 22800 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 '=' 660 nM
P11473 BXGT007709 Vitamin D3 receptor reviewed Nuclear receptor VDR Potency - 89125 nM
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 reviewed Transporter ABCC3 IC50 '=' 133000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '>' 30000 nM
Q923J1 BXGT019344 Transient receptor potential cation channel subfamily M member 7 reviewed - Trpm7 Inhibition - - -
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA FC '=' 8 -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00050 Chinese cinnamon Cinnamomum aromaticum Herbs and Spices
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease