Showing entry for Citramalyl-CoA lyase, mitochondrial


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018493
Protein NameCitramalyl-CoA lyase, mitochondrial
Uniport IdQ8N0X4
GeneCLYBL
Gene Id171425
DomainHpcH_HpaI
Pfam PF03328  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0106121 positive regulation of cobalamin metabolic process
Biological Process GO:0070207 protein homotrimerization
Biological Process GO:0106064 regulation of cobalamin metabolic process
molecular function GO:0047777 (S)-citramalyl-CoA lyase activity
molecular function GO:0016787 hydrolase activity
molecular function GO:0000287 magnesium ion binding
molecular function GO:0004474 malate synthase activity
cellular component GO:0005739 mitochondrion
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0015967 BXGD001030 Fever Pathological Conditions, Signs and Symptoms
C0023364 BXGD001638 Leptospirosis Infections
C0024790 BXGD001804 Paroxysmal nocturnal hemoglobinuria Hemic and Lymphatic Diseases
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0037369 BXGD002691 Smoking Behavior and Behavior Mechanisms
C0041296 BXGD002903 Tuberculosis Infections
C0202252 BXGD004089 VITAMIN B12 MEASUREMENT
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1519383 BXGD013237 Smoking Behaviors Behavior and Behavior Mechanisms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0006198 Citric acid 192.12
BXGC0030612 tetraethylene glycol 194.12
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein