adisease

Showing entry for Leptospirosis

General Disease Information
BXGD Id	BXGD001638
Disease Name	Leptospirosis
Disease CUI Id	C0023364
MeSH Codes	C01
Disease Class Name	Infections
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0050117
Disease Ontology Class Name	disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02750	BXGT005942	Leucine-rich alpha-2-glycoprotein	116844	reviewed
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P16157	BXGT008203	Ankyrin-1	286	reviewed
P16581	BXGT008245	E-selectin	6401	reviewed
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P20160	BXGT008548	Azurocidin	566	reviewed	Enzyme
P21796	BXGT008690	Voltage-dependent anion-selective channel protein 1	7416	reviewed
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P23141	BXGT008830	Liver carboxylesterase 1	1066	reviewed	Enzyme
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	328	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
Q00266	BXGT012515	S-adenosylmethionine synthase isoform type-1	4143	reviewed	Enzyme
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q8N0X4	BXGT018493	Citramalyl-CoA lyase, mitochondrial	171425	reviewed
Q8NBJ7	BXGT018537	Inactive C-alpha-formylglycine-generating enzyme 2	25870	reviewed
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	28234	reviewed	Transporter
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16552	BXGT023419	Interleukin-17A	3605	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}