Showing entry for Myosin-IIIa



                       
General Target Information
BXGT IdBXGT018558
Protein NameMyosin-IIIa
Uniport IdQ8NEV4
GeneMYO3A
Gene Id53904
DomainIQ; Myosin_head; Pkinase
Pfam PF00612   PF00063   PF00069  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0090103 cochlea morphogenesis
Biological Process GO:0046777 protein autophosphorylation
Biological Process GO:0050896 response to stimulus
Biological Process GO:0007605 sensory perception of sound
Biological Process GO:0007601 visual perception
molecular function GO:0003779 actin binding
molecular function GO:0030898 actin-dependent ATPase activity
molecular function GO:0043531 ADP binding
molecular function GO:0005524 ATP binding
molecular function GO:0005516 calmodulin binding
molecular function GO:0000146 microfilament motor activity
molecular function GO:0060002 plus-end directed microfilament motor activity
molecular function GO:0004672 protein kinase activity
molecular function GO:0004674 protein serine/threonine kinase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0031941 filamentous actin
cellular component GO:0030175 filopodium
cellular component GO:0032433 filopodium tip
cellular component GO:0016459 myosin complex
cellular component GO:0032426 stereocilium tip
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0452138 BXGD008831 Sensorineural hearing loss, bilateral Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1335167 BXGD012768 Ovarian Mucinous Adenocarcinoma Neoplasms
C1335177 BXGD012771 Ovarian Serous Adenocarcinoma Neoplasms
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1842138 BXGD014498 Progressive hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1843156 BXGD014561 Progressive sensorineural hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1846784 BXGD014838 Deafness, Autosomal Recessive 30 Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C3711374 BXGD019382 Nonsyndromic Deafness Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0045254 Sb-202190 331.11
BXGC0047692 Gefitinib 446.15
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein