Showing entry for Tubulin--tyrosine ligase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT018567
Protein NameTubulin--tyrosine ligase
Uniport IdQ8NG68
GeneTTL
Gene Id150465
DomainTTL
Pfam PF03133  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0018166 C-terminal protein-tyrosinylation
Biological Process GO:0000226 microtubule cytoskeleton organization
Biological Process GO:0045931 positive regulation of mitotic cell cycle
Biological Process GO:0030516 regulation of axon extension
Biological Process GO:0090235 regulation of metaphase plate congression
molecular function GO:0005524 ATP binding
molecular function GO:0004835 tubulin-tyrosine ligase activity
cellular component GO:0005876 spindle microtubule
Reactome
Pathway Id Pathway Name
R-HSA-392499 Metabolism of proteins
R-HSA-597592 Post-translational protein modification
R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C1261473 BXGD011855 Sarcoma Neoplasms
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C4551686 BXGD023391 Malignant neoplasm of soft tissue Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0001625 L-2-Amino-3-(4-aminophenyl)propanoic acid 180.2
BXGC0013237 Tyrosine 181.07
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein