Showing entry for Adult Fibrosarcoma


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006545
Disease NameAdult Fibrosarcoma
Disease CUI IdC0278595
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7   DOID:14566  
Disease Ontology Class Namedisease of anatomical entity; disease of cellular proliferation
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15119 BXGT004128 T-box transcription factor TBX3 6926 reviewed Transcription factor
O15151 BXGT004132 Protein Mdm4 4194 reviewed Nucleic acid binding
O43597 BXGT004602 Protein sprouty homolog 2 10253 reviewed Signaling
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75581 BXGT005136 Low-density lipoprotein receptor-related protein 6 4040 reviewed
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic 3417 reviewed
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P00492 BXGT005556 Hypoxanthine-guanine phosphoribosyltransferase 3251 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01275 BXGT005747 Glucagon 2641 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02818 BXGT005969 Osteocalcin 632 reviewed
P03950 BXGT006116 Angiogenin 283 reviewed
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04004 BXGT006125 Vitronectin 7448 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05771 BXGT006384 Protein kinase C beta type 5579 reviewed Kinase
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07602 BXGT006646 Prosaposin 5660 reviewed
P07741 BXGT006666 Adenine phosphoribosyltransferase 353 reviewed
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08047 BXGT006720 Transcription factor Sp1 6667 reviewed Nucleic acid binding
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P08842 BXGT006830 Steryl-sulfatase 412 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10301 BXGT007556 Ras-related protein R-Ras 6237 reviewed Enzyme modulator
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11387 BXGT007696 DNA topoisomerase 1 7150 reviewed Enzyme
P11498 BXGT007714 Pyruvate carboxylase, mitochondrial 5091 reviewed Enzyme
P12429 BXGT007814 Annexin A3 306 reviewed
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14784 BXGT008054 Interleukin-2 receptor subunit beta 3560 reviewed Receptor
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P15151 BXGT008089 Poliovirus receptor 5817 reviewed
P15153 BXGT008090 Ras-related C3 botulinum toxin substrate 2 5880 reviewed Enzyme modulator
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16070 BXGT008186 CD44 antigen 960 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P17735 BXGT008335 Tyrosine aminotransferase 6898 reviewed
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P19021 BXGT008449 Peptidyl-glycine alpha-amidating monooxygenase 5066 reviewed Enzyme
P19367 BXGT008476 Hexokinase-1 3098 reviewed Kinase
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21333 BXGT008638 Filamin-A 2316 reviewed
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P23458 BXGT008868 Tyrosine-protein kinase JAK1 3716 reviewed Kinase
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P31350 BXGT009526 Ribonucleoside-diphosphate reductase subunit M2 6241 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33176 BXGT009699 Kinesin-1 heavy chain 3799 reviewed Cellular structure
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P40933 BXGT010209 Interleukin-15 3600 reviewed
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42575 BXGT010318 Caspase-2 835 reviewed Enzyme
P43246 BXGT010371 DNA mismatch repair protein Msh2 4436 reviewed Nucleic acid binding
P43490 BXGT010395 Nicotinamide phosphoribosyltransferase 10135 reviewed Signaling
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49023 BXGT010672 Paxillin 5829 reviewed Cellular structure
P49763 BXGT010737 Placenta growth factor 5228 reviewed Signaling
P49767 BXGT010739 Vascular endothelial growth factor C 7424 reviewed Signaling
P49841 BXGT010750 Glycogen synthase kinase-3 beta 2932 reviewed Kinase
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P52756 BXGT010950 RNA-binding protein 5 10181 reviewed
P53671 BXGT011009 LIM domain kinase 2 3985 reviewed Kinase
P54760 BXGT011075 Ephrin type-B receptor 4 2050 reviewed Kinase
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62330 BXGT011423 ADP-ribosylation factor 6 382 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78358 BXGT011838 Cancer/testis antigen 1 246100 reviewed
P78504 BXGT011844 Protein jagged-1 182 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q06830 BXGT012894 Peroxiredoxin-1 5052 reviewed Enzyme
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q13126 BXGT013313 S-methyl-5'-thioadenosine phosphorylase 4507 reviewed Enzyme
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 5058 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13188 BXGT013324 Serine/threonine-protein kinase 3 6788 reviewed Kinase
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13526 BXGT013369 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 5300 reviewed
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q14117 BXGT013443 Dihydropyrimidinase 1807 reviewed Enzyme
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14872 BXGT013511 Metal regulatory transcription factor 1 4520 reviewed Transcription factor
Q15078 BXGT013534 Cyclin-dependent kinase 5 activator 1 8851 reviewed Enzyme modulator
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15185 BXGT013549 Prostaglandin E synthase 3 10728 reviewed Chaperone
Q15554 BXGT013577 Telomeric repeat-binding factor 2 7014 reviewed
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q16288 BXGT013625 NT-3 growth factor receptor 4916 reviewed Kinase
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q86TM3 BXGT017607 Probable ATP-dependent RNA helicase DDX53 168400 reviewed
Q8N4C8 BXGT018510 Misshapen-like kinase 1 50488 reviewed Kinase
Q8NB16 BXGT018535 Mixed lineage kinase domain-like protein 197259 reviewed Kinase
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q8NG68 BXGT018567 Tubulin--tyrosine ligase 150465 reviewed
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q92945 BXGT019397 Far upstream element-binding protein 2 8570 reviewed Enzyme
Q96GD0 BXGT019665 Pyridoxal phosphate phosphatase 57026 reviewed Enzyme
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q96RJ3 BXGT019729 Tumor necrosis factor receptor superfamily member 13C 115650 reviewed
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 4217 reviewed Kinase
Q9BYW2 BXGT020192 Histone-lysine N-methyltransferase SETD2 29072 reviewed Epigenetic regulator
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9H7B4 BXGT020490 Histone-lysine N-methyltransferase SMYD3 64754 reviewed Epigenetic regulator
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9NYL2 BXGT021259 Mitogen-activated protein kinase kinase kinase 20 51776 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBZ9 BXGT021666 DNA repair protein REV1 51455 reviewed
Q9UHI8 BXGT021701 A disintegrin and metalloproteinase with thrombospondin motifs 1 9510 reviewed Enzyme
Q9UHX3 BXGT021708 Adhesion G protein-coupled receptor E2 30817 reviewed G-protein coupled receptor
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UKV5 BXGT021751 E3 ubiquitin-protein ligase AMFR 267 reviewed
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPZ9 BXGT021804 Serine/threonine-protein kinase ICK 22858 reviewed Kinase
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y286 BXGT022225 Sialic acid-binding Ig-like lectin 7 27036 reviewed Receptor
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
O43148 BXGT023017 mRNA cap guanine-N7 methyltransferase 8731 reviewed
P09622 BXGT023116 Dihydrolipoyl dehydrogenase, mitochondrial 1738 reviewed Enzyme
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q08AF3 BXGT025474 Schlafen family member 5 162394 reviewed
Q9UKB1 BXGT025928 F-box/WD repeat-containing protein 11 23291 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease