Showing entry for BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019022
Protein NameBTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1
Uniport IdQ8WZ19
GeneKCTD13
Gene Id253980
DomainBTB_2
Pfam PF02214  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0016477 cell migration
Biological Process GO:0006260 DNA replication
Biological Process GO:0035024 negative regulation of Rho protein signal transduction
Biological Process GO:0045740 positive regulation of DNA replication
Biological Process GO:0050806 positive regulation of synaptic transmission
Biological Process GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
Biological Process GO:0051260 protein homooligomerization
Biological Process GO:0016567 protein ubiquitination
Biological Process GO:0043149 stress fiber assembly
molecular function GO:0017049 GTP-Rho binding
molecular function GO:0042802 identical protein binding
molecular function GO:0019904 protein domain specific binding
cellular component GO:0031463 Cul3-RING ubiquitin ligase complex
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0025958 BXGD001882 Microcephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0337443 BXGD007161 Sodium measurement
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C1305855 BXGD012348 Body mass index
C1314691 BXGD012388 Age at menarche Behavior and Behavior Mechanisms
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C2363813 BXGD017107 Short-term memory impairment
C4528257 BXGD023159 Corpuscular Hemoglobin Concentration Mean
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein