Showing entry for Pervasive Development Disorder


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD009229
Disease NamePervasive Development Disorder
Disease CUI IdC0524528
MeSH Codes F03  
Disease Class NameMental Disorders
Semantic TypeMental or Behavioral Dysfunction
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A1Z1Q3 BXGT001069 ADP-ribose glycohydrolase MACROD2 140733 reviewed
O00222 BXGT003899 Metabotropic glutamate receptor 8 2918 reviewed G-protein coupled receptor
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00767 BXGT003949 Acyl-CoA desaturase 6319 reviewed
O14936 BXGT004114 Peripheral plasma membrane protein CASK 8573 reviewed Kinase
O14980 BXGT004119 Exportin-1 7514 reviewed Receptor
O15409 BXGT004166 Forkhead box protein P2 93986 reviewed
O43272 BXGT004580 Proline dehydrogenase 1, mitochondrial 5625 reviewed Enzyme
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O43683 BXGT004614 Mitotic checkpoint serine/threonine-protein kinase BUB1 699 reviewed Kinase
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60285 BXGT004867 NUAK family SNF1-like kinase 1 9891 reviewed Kinase
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75390 BXGT005123 Citrate synthase, mitochondrial 1431 reviewed Enzyme
O75746 BXGT005148 Calcium-binding mitochondrial carrier protein Aralar1 8604 reviewed Transporter
O94759 BXGT005327 Transient receptor potential cation channel subfamily M member 2 7226 reviewed Ion channel
P00352 BXGT005510 Retinal dehydrogenase 1 216 reviewed Enzyme
P01112 BXGT005732 GTPase HRas 3265 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01303 BXGT005748 Pro-neuropeptide Y 4852 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02671 BXGT005914 Fibrinogen alpha chain 2243 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04745 BXGT006255 Alpha-amylase 1 278 reviewed
P05067 BXGT006306 Amyloid-beta precursor protein 351 reviewed Enzyme modulator
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05108 BXGT006317 Cholesterol side-chain cleavage enzyme, mitochondrial 1583 reviewed
P05177 BXGT006336 Cytochrome P450 1A2 1544 reviewed Enzyme
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P07108 BXGT006551 Acyl-CoA-binding protein 1622 reviewed Enzyme modulator
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10412 BXGT007566 Histone H1.4 3008 reviewed Nucleic acid binding
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 6515 reviewed Transporter
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P14207 BXGT007993 Folate receptor beta 2350 reviewed
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15328 BXGT008108 Folate receptor alpha 2348 reviewed
P15538 BXGT008137 Cytochrome P450 11B1, mitochondrial 1584 reviewed
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 1141 reviewed Ion channel
P18074 BXGT008374 General transcription and DNA repair factor IIH helicase subunit XPD 2068 reviewed Enzyme
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P20472 BXGT008578 Parvalbumin alpha 5816 reviewed Calcium-binding protein
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22309 BXGT008753 UDP-glucuronosyltransferase 1-1 54658 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23975 BXGT008935 Sodium-dependent noradrenaline transporter 6530 reviewed Transporter
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28329 BXGT009251 Choline O-acetyltransferase 1103 reviewed Enzyme
P28331 BXGT009252 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial 4719 reviewed Enzyme
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29274 BXGT009327 Adenosine receptor A2a 135 reviewed G-protein coupled receptor
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30531 BXGT009432 Sodium- and chloride-dependent GABA transporter 1 6529 reviewed Transporter
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P34969 BXGT009777 5-hydroxytryptamine receptor 7 3363 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35462 BXGT009835 D(3) dopamine receptor 1814 reviewed G-protein coupled receptor
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P37288 BXGT009977 Vasopressin V1a receptor 552 reviewed G-protein coupled receptor
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P41229 BXGT010239 Lysine-specific demethylase 5C 8242 reviewed
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42858 BXGT010341 Huntingtin 3064 reviewed
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43005 BXGT010349 Excitatory amino acid transporter 3 6505 reviewed Transporter
P43354 BXGT010381 Nuclear receptor subfamily 4 group A member 2 4929 reviewed Nuclear receptor
P47895 BXGT010593 Aldehyde dehydrogenase family 1 member A3 220 reviewed Enzyme
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48169 BXGT010622 Gamma-aminobutyric acid receptor subunit alpha-4 2557 reviewed Ion channel
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P51531 BXGT010851 Probable global transcription activator SNF2L2 6595 reviewed Epigenetic regulator
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 6197 reviewed Kinase
P52594 BXGT010936 Arf-GAP domain and FG repeat-containing protein 1 3267 reviewed
P52788 BXGT010953 Spermine synthase 6611 reviewed
P54756 BXGT011074 Ephrin type-A receptor 5 2044 reviewed Kinase
P58400 BXGT011235 Neurexin-1-beta 9378 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P62166 BXGT011412 Neuronal calcium sensor 1 23413 reviewed
P62258 BXGT011415 14-3-3 protein epsilon 7531 reviewed Chaperone
P62753 BXGT011454 40S ribosomal protein S6 6194 reviewed Nucleic acid binding
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
Q01668 BXGT012605 Voltage-dependent L-type calcium channel subunit alpha-1D 776 reviewed Ion channel
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q04760 BXGT012782 Lactoylglutathione lyase 2739 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q10588 BXGT013202 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 683 reviewed Enzyme
Q12756 BXGT013261 Kinesin-like protein KIF1A 547 reviewed Cellular structure
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q12882 BXGT013276 Dihydropyrimidine dehydrogenase [NADP(+)] 1806 reviewed Enzyme
Q13002 BXGT013303 Glutamate receptor ionotropic, kainate 2 2898 reviewed Ion channel
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13224 BXGT013328 Glutamate receptor ionotropic, NMDA 2B 2904 reviewed Ion channel
Q13426 BXGT013353 DNA repair protein XRCC4 7518 reviewed
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13936 BXGT013404 Voltage-dependent L-type calcium channel subunit alpha-1C 775 reviewed Ion channel
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q15185 BXGT013549 Prostaglandin E synthase 3 10728 reviewed Chaperone
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16674 BXGT013655 Melanoma-derived growth regulatory protein 8190 reviewed
Q8N0W4 BXGT018492 Neuroligin-4, X-linked 57502 reviewed
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q8WZ19 BXGT019022 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 253980 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96NI6 BXGT019699 Leucine-rich repeat and fibronectin type-III domain-containing protein 5 145581 reviewed
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q99497 BXGT019926 Protein/nucleic acid deglycase DJ-1 11315 reviewed Enzyme
Q99572 BXGT019935 P2X purinoceptor 7 5027 reviewed Ion channel
Q9BUB5 BXGT020133 MAP kinase-interacting serine/threonine-protein kinase 1 8569 reviewed Kinase
Q9BUL9 BXGT020136 Ribonuclease P protein subunit p25 54913 reviewed Enzyme
Q9BXJ9 BXGT020170 N-alpha-acetyltransferase 15, NatA auxiliary subunit 80155 reviewed Enzyme
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HAR2 BXGT020506 Adhesion G protein-coupled receptor L3 23284 reviewed G-protein coupled receptor
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NQX3 BXGT021172 Gephyrin 10243 reviewed
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9NY46 BXGT021248 Sodium channel protein type 3 subunit alpha 6328 reviewed Ion channel
Q9NZN1 BXGT021279 Interleukin-1 receptor accessory protein-like 1 11141 reviewed Receptor
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UL54 BXGT021755 Serine/threonine-protein kinase TAO2 9344 reviewed Kinase
Q9UP65 BXGT021795 Cytosolic phospholipase A2 gamma 8605 reviewed Enzyme
Q9UQD0 BXGT021811 Sodium channel protein type 8 subunit alpha 6334 reviewed Ion channel
P20036 BXGT022764 HLA class II histocompatibility antigen, DP alpha 1 chain 3113 reviewed Immune response
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
P25054 BXGT022961 Adenomatous polyposis coli protein 324 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q9UBP0 BXGT023601 Spastin 6683 reviewed Cellular structure
P07954 BXGT023939 Fumarate hydratase, mitochondrial 2271 reviewed Enzyme
Q9H5Q4 BXGT023970 Dimethyladenosine transferase 2, mitochondrial 64216 reviewed
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
Q96DA2 BXGT025522 Ras-related protein Rab-39B 116442 reviewed
Q05086 BXGT025648 Ubiquitin-protein ligase E3A 7337 reviewed
Q9P2E7 BXGT025815 Protocadherin-10 57575 reviewed
Q8TAB3 BXGT025819 Protocadherin-19 57526 reviewed
P35251 BXGT025853 Replication factor C subunit 1 5981 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease