Showing entry for Kremen protein 1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019698
Protein NameKremen protein 1
Uniport IdQ96MU8
GeneKREMEN1
Gene Id83999
DomainCUB; Kringle; WSC
Pfam PF00431   PF00051   PF01822  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006915 apoptotic process
Biological Process GO:0007154 cell communication
Biological Process GO:0060173 limb development
Biological Process GO:0048681 negative regulation of axon regeneration
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0030279 negative regulation of ossification
Biological Process GO:0060828 regulation of canonical Wnt signaling pathway
Biological Process GO:0016055 Wnt signaling pathway
cellular component GO:0016021 integral component of membrane
cellular component GO:0016020 membrane
cellular component GO:0043025 neuronal cell body
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1643685 Disease
R-HSA-195721 Signaling by WNT
R-HSA-195721 Signaling by WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-3772470 Negative regulation of TCF-dependent signaling by WNT ligand antagonists
R-HSA-4791275 Signaling by WNT in cancer
R-HSA-5339717 Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
R-HSA-5663202 Diseases of signal transduction by growth factor receptors and second messengers
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000846 BXGD000015 Agenesis
C0013575 BXGD000854 Ectodermal Dysplasia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0014378 BXGD000912 Enterovirus Infections Infections
C0020608 BXGD001443 Hypodontia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
C0026764 BXGD001928 Multiple Myeloma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases; Cardiovascular Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038013 BXGD002725 Ankylosing spondylitis Musculoskeletal Diseases
C0175754 BXGD004015 Agenesis of corpus callosum Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0206624 BXGD004190 Hepatoblastoma Neoplasms
C0282160 BXGD006797 Aplasia Cutis Congenita Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0432272 BXGD008761 Van Buchem disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0949690 BXGD011584 Spondylarthritis Musculoskeletal Diseases
C0949691 BXGD011585 Spondylarthropathies Musculoskeletal Diseases
C1800706 BXGD013755 Idiopathic Pulmonary Fibrosis Respiratory Tract Diseases
C1842366 BXGD014512 Low anterior hairline
C1843300 BXGD014572 Sparse eyelashes
C4082304 BXGD022090 Oligodontia
C4281771 BXGD022414 Thin eyebrow
C4479322 BXGD022932 ECTODERMAL DYSPLASIA 13, HAIR/TOOTH TYPE
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002586 Calcium 40.08
BXGC0003705 Chloride 35.45
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein