adisease

Showing entry for Hypodontia

General Disease Information
BXGD Id	BXGD001443
Disease Name	Hypodontia
Disease CUI Id	C0020608
MeSH Codes	C16 C07
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Stomatognathic Diseases
Semantic Type	Congenital Abnormality
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00443	BXGT003920	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	5286	reviewed	Kinase
O00555	BXGT003936	Voltage-dependent P/Q-type calcium channel subunit alpha-1A	773	reviewed	Ion channel
O14746	BXGT004091	Telomerase reverse transcriptase	7015	reviewed	Enzyme
O14939	BXGT004115	Phospholipase D2	5338	reviewed
O15119	BXGT004128	T-box transcription factor TBX3	6926	reviewed	Transcription factor
O15399	BXGT004164	Glutamate receptor ionotropic, NMDA 2D	2906	reviewed	Ion channel
O15550	BXGT004179	Lysine-specific demethylase 6A	7403	reviewed	Epigenetic regulator
O43896	BXGT004632	Kinesin-like protein KIF1C	10749	reviewed	Cellular structure
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O75581	BXGT005136	Low-density lipoprotein receptor-related protein 6	4040	reviewed
O75844	BXGT005156	CAAX prenyl protease 1 homolog	10269	reviewed	Enzyme
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O96028	BXGT005417	Histone-lysine N-methyltransferase NSD2	7468	reviewed	Epigenetic regulator
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P08151	BXGT006731	Zinc finger protein GLI1	2735	reviewed
P10600	BXGT007584	Transforming growth factor beta-3 proprotein	7043	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12830	BXGT007852	Cadherin-1	999	reviewed
P15924	BXGT008171	Desmoplakin	1832	reviewed	Cellular structure
P16144	BXGT008200	Integrin beta-4	3691	reviewed	Receptor
P16389	BXGT008221	Potassium voltage-gated channel subfamily A member 2	3737	reviewed	Ion channel
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P21333	BXGT008638	Filamin-A	2316	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P25963	BXGT009080	NF-kappa-B inhibitor alpha	4792	reviewed
P27482	BXGT009185	Calmodulin-like protein 3	810	reviewed	Calcium-binding protein
P27986	BXGT009216	Phosphatidylinositol 3-kinase regulatory subunit alpha	5295	reviewed	Kinase
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43026	BXGT010351	Growth/differentiation factor 5	8200	reviewed	Signaling
P43235	BXGT010368	Cathepsin K	1513	reviewed	Enzyme
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	2561	reviewed	Ion channel
P49588	BXGT010713	Alanine--tRNA ligase, cytoplasmic	16	reviewed	Nucleic acid binding
P51812	BXGT010893	Ribosomal protein S6 kinase alpha-3	6197	reviewed	Kinase
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P61224	BXGT011370	Ras-related protein Rap-1b	5908	reviewed	Enzyme modulator
P61978	BXGT011399	Heterogeneous nuclear ribonucleoprotein K	3190	reviewed	Enzyme
P61981	BXGT011400	14-3-3 protein gamma	7532	reviewed	Chaperone
P62834	BXGT011464	Ras-related protein Rap-1A	5906	reviewed	Enzyme modulator
P63165	BXGT011506	Small ubiquitin-related modifier 1	7341	reviewed
Q00610	BXGT012539	Clathrin heavy chain 1	1213	reviewed	Transporter
Q00975	BXGT012558	Voltage-dependent N-type calcium channel subunit alpha-1B	774	reviewed	Ion channel
Q01974	BXGT012628	Tyrosine-protein kinase transmembrane receptor ROR2	4920	reviewed	Kinase
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	5745	reviewed	G-protein coupled receptor
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q08209	BXGT012968	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	5530	reviewed
Q13363	BXGT013344	C-terminal-binding protein 1	1487	reviewed	Transcription factor
Q13698	BXGT013392	Voltage-dependent L-type calcium channel subunit alpha-1S	779	reviewed	Ion channel
Q14332	BXGT013462	Frizzled-2	2535	reviewed	G-protein coupled receptor
Q14721	BXGT013502	Potassium voltage-gated channel subfamily B member 1	3745	reviewed	Ion channel
Q15067	BXGT013532	Peroxisomal acyl-coenzyme A oxidase 1	51	reviewed	Enzyme
Q15223	BXGT013551	Nectin-1	5818	reviewed
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q6NUK1	BXGT016429	Calcium-binding mitochondrial carrier protein SCaMC-1	29957	reviewed	Transporter
Q7L3T8	BXGT016994	Probable proline--tRNA ligase, mitochondrial	25973	reviewed	Enzyme
Q8NET8	BXGT018557	Transient receptor potential cation channel subfamily V member 3	162514	reviewed	Ion channel
Q96MU8	BXGT019698	Kremen protein 1	83999	reviewed	Receptor
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9GZZ9	BXGT020430	Ubiquitin-like modifier-activating enzyme 5	79876	reviewed	Enzyme
Q9H4W6	BXGT020478	Transcription factor COE3	253738	reviewed
Q9NY46	BXGT021248	Sodium channel protein type 3 subunit alpha	6328	reviewed	Ion channel
Q9UQD0	BXGT021811	Sodium channel protein type 8 subunit alpha	6334	reviewed	Ion channel
Q9Y6K9	BXGT022333	NF-kappa-B essential modulator	8517	reviewed	Kinase
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed
Q96L73	BXGT024676	Histone-lysine N-methyltransferase, H3 lysine-36 specific	64324	reviewed	Epigenetic regulator
P38646	BXGT024954	Stress-70 protein, mitochondrial	3313	reviewed
P35250	BXGT025854	Replication factor C subunit 2	5982	reviewed	Enzyme
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme
Q8WXI2	BXGT026145	Connector enhancer of kinase suppressor of ras 2	22866	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}