Showing entry for Idiopathic Pulmonary Fibrosis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD013755
Disease NameIdiopathic Pulmonary Fibrosis
Disease CUI IdC1800706
MeSH Codes C08  
Disease Class NameRespiratory Tract Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00418 BXGT003918 Eukaryotic elongation factor 2 kinase 29904 reviewed Kinase
O00429 BXGT003919 Dynamin-1-like protein 10059 reviewed Enzyme modulator
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O14763 BXGT004093 Tumor necrosis factor receptor superfamily member 10B 8795 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15392 BXGT004162 Baculoviral IAP repeat-containing protein 5 332 reviewed Enzyme modulator
O15438 BXGT004168 Canalicular multispecific organic anion transporter 2 8714 reviewed Transporter
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O43175 BXGT004575 D-3-phosphoglycerate dehydrogenase 26227 reviewed Enzyme
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O43557 BXGT004600 Tumor necrosis factor ligand superfamily member 14 8740 reviewed Signaling
O43597 BXGT004602 Protein sprouty homolog 2 10253 reviewed Signaling
O43809 BXGT004627 Cleavage and polyadenylation specificity factor subunit 5 11051 reviewed Nucleic acid binding
O43813 BXGT004628 Glutathione S-transferase LANCL1 10314 reviewed
O43915 BXGT004636 Vascular endothelial growth factor D 2277 reviewed Signaling
O60486 BXGT004877 Plexin-C1 10154 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75015 BXGT005095 Low affinity immunoglobulin gamma Fc region receptor III-B 2215 reviewed Cell adhesion
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 8989 reviewed Ion channel
O94766 BXGT005330 Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 26229 reviewed Enzyme
O94768 BXGT005331 Serine/threonine-protein kinase 17B 9262 reviewed Kinase
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O96020 BXGT005416 G1/S-specific cyclin-E2 9134 reviewed Enzyme modulator
P00338 BXGT005504 L-lactate dehydrogenase A chain 3939 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00749 BXGT005641 Urokinase-type plasminogen activator 5328 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01100 BXGT005727 Proto-oncogene c-Fos 2353 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02100 BXGT005845 Hemoglobin subunit epsilon 3046 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02461 BXGT005880 Collagen alpha-1(III) chain 1281 reviewed
P02511 BXGT005885 Alpha-crystallin B chain 1410 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02760 BXGT005948 Protein AMBP 259 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 2064 reviewed Kinase
P04629 BXGT006239 High affinity nerve growth factor receptor 4914 reviewed Kinase
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05187 BXGT006339 Alkaline phosphatase, placental type 250 reviewed Enzyme
P05230 BXGT006344 Fibroblast growth factor 1 2246 reviewed Signaling
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P05787 BXGT006385 Keratin, type II cytoskeletal 8 3856 reviewed
P06276 BXGT006430 Cholinesterase 590 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06731 BXGT006488 Carcinoembryonic antigen-related cell adhesion molecule 5 1048 reviewed
P07355 BXGT006609 Annexin A2 302 reviewed
P07711 BXGT006661 Cathepsin L1 1514 reviewed Enzyme
P07814 BXGT006680 Bifunctional glutamate/proline--tRNA ligase 2058 reviewed Enzyme
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08100 BXGT006725 Rhodopsin 6010 reviewed G-protein coupled receptor
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08174 BXGT006739 Complement decay-accelerating factor 1604 reviewed
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08238 BXGT006753 Heat shock protein HSP 90-beta 3326 reviewed Chaperone
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08648 BXGT006804 Integrin alpha-5 3678 reviewed
P08670 BXGT006810 Vimentin 7431 reviewed
P08758 BXGT006821 Annexin A5 308 reviewed
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P08887 BXGT006835 Interleukin-6 receptor subunit alpha 3570 reviewed Signaling
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09486 BXGT006897 SPARC 6678 reviewed Signaling
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09619 BXGT006911 Platelet-derived growth factor receptor beta 5159 reviewed Kinase
P09874 BXGT006934 Poly [ADP-ribose] polymerase 1 142 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P09923 BXGT006942 Intestinal-type alkaline phosphatase 248 reviewed Enzyme
P09960 BXGT006952 Leukotriene A-4 hydrolase 4048 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10619 BXGT007589 Lysosomal protective protein 5476 reviewed Enzyme
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10997 BXGT007643 Islet amyloid polypeptide 3375 reviewed Signaling
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP 3309 reviewed
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12318 BXGT007799 Low affinity immunoglobulin gamma Fc region receptor II-a 2212 reviewed Cell adhesion
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13236 BXGT007891 C-C motif chemokine 4 6351 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13647 BXGT007937 Keratin, type II cytoskeletal 5 3852 reviewed
P14207 BXGT007993 Folate receptor beta 2350 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] 3248 reviewed
P15529 BXGT008134 Membrane cofactor protein 4179 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P15941 BXGT008176 Mucin-1 4582 reviewed
P16157 BXGT008203 Ankyrin-1 286 reviewed
P16278 BXGT008213 Beta-galactosidase 2720 reviewed Enzyme
P16591 BXGT008246 Tyrosine-protein kinase Fer 2241 reviewed Kinase
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P17301 BXGT008299 Integrin alpha-2 3673 reviewed
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17861 BXGT008348 X-box-binding protein 1 7494 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P18848 BXGT008432 Cyclic AMP-dependent transcription factor ATF-4 468 reviewed
P18887 BXGT008437 DNA repair protein XRCC1 7515 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19440 BXGT008481 Glutathione hydrolase 1 proenzyme 2678 reviewed Enzyme
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P20248 BXGT008554 Cyclin-A2 890 reviewed Enzyme modulator
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21291 BXGT008635 Cysteine and glycine-rich protein 1 1465 reviewed Cellular structure
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21579 BXGT008665 Synaptotagmin-1 6857 reviewed Transporter
P21583 BXGT008667 Kit ligand 4254 reviewed
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P21802 BXGT008691 Fibroblast growth factor receptor 2 2263 reviewed Kinase
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24593 BXGT008979 Insulin-like growth factor-binding protein 5 3488 reviewed Enzyme modulator
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P25025 BXGT009006 C-X-C chemokine receptor type 2 3579 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25325 BXGT009038 3-mercaptopyruvate sulfurtransferase 4357 reviewed Enzyme
P25774 BXGT009066 Cathepsin S 1520 reviewed Enzyme
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P26012 BXGT009083 Integrin beta-8 3696 reviewed Receptor
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P28223 BXGT009239 5-hydroxytryptamine receptor 2A 3356 reviewed G-protein coupled receptor
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28908 BXGT009302 Tumor necrosis factor receptor superfamily member 8 943 reviewed
P29275 BXGT009328 Adenosine receptor A2b 136 reviewed G-protein coupled receptor
P29320 BXGT009332 Ephrin type-A receptor 3 2042 reviewed Kinase
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29400 BXGT009343 Collagen alpha-5(IV) chain 1287 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P29508 BXGT009358 Serpin B3 6317 reviewed Enzyme modulator
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P31751 BXGT009576 RAC-beta serine/threonine-protein kinase 208 reviewed Kinase
P32004 BXGT009594 Neural cell adhesion molecule L1 3897 reviewed
P32302 BXGT009619 C-X-C chemokine receptor type 5 643 reviewed G-protein coupled receptor
P34897 BXGT009768 Serine hydroxymethyltransferase, mitochondrial 6472 reviewed Enzyme
P34931 BXGT009771 Heat shock 70 kDa protein 1-like 3305 reviewed
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P34969 BXGT009777 5-hydroxytryptamine receptor 7 3363 reviewed G-protein coupled receptor
P34972 BXGT009779 Cannabinoid receptor 2 1269 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P35813 BXGT009869 Protein phosphatase 1A 5494 reviewed Enzyme
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P36969 BXGT009949 Phospholipid hydroperoxide glutathione peroxidase 2879 reviewed Enzyme
P37173 BXGT009970 TGF-beta receptor type-2 7048 reviewed Kinase
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P41597 BXGT010268 C-C chemokine receptor type 2 729230 reviewed
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P45452 BXGT010462 Collagenase 3 4322 reviewed Enzyme
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46108 BXGT010509 Adapter molecule crk 1398 reviewed
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P46939 BXGT010555 Utrophin 7402 reviewed
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49137 BXGT010680 MAP kinase-activated protein kinase 2 9261 reviewed Kinase
P49662 BXGT010724 Caspase-4 837 reviewed Enzyme
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P49908 BXGT010760 Selenoprotein P 6414 reviewed Extracellular structure
P50052 BXGT010768 Type-2 angiotensin II receptor 186 reviewed G-protein coupled receptor
P50579 BXGT010812 Methionine aminopeptidase 2 10988 reviewed
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51580 BXGT010864 Thiopurine S-methyltransferase 7172 reviewed
P51665 BXGT010874 26S proteasome non-ATPase regulatory subunit 7 5713 reviewed Enzyme
P52789 BXGT010954 Hexokinase-2 3099 reviewed Kinase
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 5347 reviewed Kinase
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 5563 reviewed Kinase
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P54829 BXGT011085 Tyrosine-protein phosphatase non-receptor type 5 84867 reviewed
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55265 BXGT011117 Double-stranded RNA-specific adenosine deaminase 103 reviewed Enzyme
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
P56373 BXGT011164 P2X purinoceptor 3 5024 reviewed Ion channel
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P61587 BXGT011376 Rho-related GTP-binding protein RhoE 390 reviewed Enzyme modulator
P62805 BXGT011457 Histone H4 8370 reviewed
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P68363 BXGT011594 Tubulin alpha-1B chain 10376 reviewed Cellular structure
P78504 BXGT011844 Protein jagged-1 182 reviewed
P78527 BXGT011846 DNA-dependent protein kinase catalytic subunit 5591 reviewed Kinase
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P78563 BXGT011850 Double-stranded RNA-specific editase 1 104 reviewed Enzyme
P80075 BXGT011876 C-C motif chemokine 8 6355 reviewed Signaling
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
P98170 BXGT012231 E3 ubiquitin-protein ligase XIAP 331 reviewed Enzyme modulator
Q01094 BXGT012568 Transcription factor E2F1 1869 reviewed Nucleic acid binding
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q02779 BXGT012670 Mitogen-activated protein kinase kinase kinase 10 4294 reviewed Kinase
Q02809 BXGT012674 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 5351 reviewed Enzyme
Q04206 BXGT012754 Transcription factor p65 5970 reviewed Transcription factor
Q04756 BXGT012780 Hepatocyte growth factor activator 3083 reviewed Enzyme
Q05397 BXGT012815 Focal adhesion kinase 1 5747 reviewed Kinase
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06187 BXGT012860 Tyrosine-protein kinase BTK 695 reviewed Kinase
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 7301 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q08050 BXGT012958 Forkhead box protein M1 2305 reviewed
Q08345 BXGT012982 Epithelial discoidin domain-containing receptor 1 780 reviewed Kinase
Q08722 BXGT013002 Leukocyte surface antigen CD47 961 reviewed
Q08881 BXGT013012 Tyrosine-protein kinase ITK/TSK 3702 reviewed Kinase
Q09472 BXGT013038 Histone acetyltransferase p300 2033 reviewed
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q12866 BXGT013273 Tyrosine-protein kinase Mer 10461 reviewed Kinase
Q12923 BXGT013281 Tyrosine-protein phosphatase non-receptor type 13 5783 reviewed
Q13009 BXGT013305 T-lymphoma invasion and metastasis-inducing protein 1 7074 reviewed
Q13131 BXGT013314 5'-AMP-activated protein kinase catalytic subunit alpha-1 5562 reviewed Kinase
Q13155 BXGT013320 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 7965 reviewed
Q13164 BXGT013322 Mitogen-activated protein kinase 7 5598 reviewed Kinase
Q13188 BXGT013324 Serine/threonine-protein kinase 3 6788 reviewed Kinase
Q13309 BXGT013338 S-phase kinase-associated protein 2 6502 reviewed
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q13563 BXGT013377 Polycystin-2 5311 reviewed Ion channel
Q13822 BXGT013396 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 5168 reviewed Enzyme
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q14002 BXGT013433 Carcinoembryonic antigen-related cell adhesion molecule 7 1087 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14332 BXGT013462 Frizzled-2 2535 reviewed G-protein coupled receptor
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14576 BXGT013487 ELAV-like protein 3 1995 reviewed
Q15020 BXGT013522 Squamous cell carcinoma antigen recognized by T-cells 3 9733 reviewed Nucleic acid binding
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15116 BXGT013539 Programmed cell death protein 1 5133 reviewed
Q15139 BXGT013546 Serine/threonine-protein kinase D1 5587 reviewed Kinase
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q16584 BXGT013642 Mitogen-activated protein kinase kinase kinase 11 4296 reviewed Kinase
Q16637 BXGT013646 Survival motor neuron protein 6607 reviewed Epigenetic regulator
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16853 BXGT013683 Membrane primary amine oxidase 8639 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q6ZN17 BXGT016631 Protein lin-28 homolog B 389421 reviewed
Q76MJ5 BXGT016871 Serine/threonine-protein kinase/endoribonuclease IRE2 10595 reviewed Kinase
Q7KZI7 BXGT016990 Serine/threonine-protein kinase MARK2 2011 reviewed Kinase
Q8N6T7 BXGT018525 NAD-dependent protein deacetylase sirtuin-6 51548 reviewed Epigenetic regulator
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8WUI4 BXGT018992 Histone deacetylase 7 51564 reviewed Epigenetic regulator
Q8WY64 BXGT019017 E3 ubiquitin-protein ligase MYLIP 29116 reviewed
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92956 BXGT019399 Tumor necrosis factor receptor superfamily member 14 8764 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96F46 BXGT019656 Interleukin-17 receptor A 23765 reviewed
Q96HS1 BXGT019672 Serine/threonine-protein phosphatase PGAM5, mitochondrial 192111 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q96MU8 BXGT019698 Kremen protein 1 83999 reviewed Receptor
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99519 BXGT019928 Sialidase-1 4758 reviewed Enzyme
Q99527 BXGT019930 G-protein coupled estrogen receptor 1 2852 reviewed G-protein coupled receptor
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZ11 BXGT020193 Disintegrin and metalloproteinase domain-containing protein 33 80332 reviewed Enzyme
Q9C000 BXGT020206 NACHT, LRR and PYD domains-containing protein 1 22861 reviewed
Q9GZT4 BXGT020424 Serine racemase 63826 reviewed Enzyme
Q9H2X6 BXGT020458 Homeodomain-interacting protein kinase 2 28996 reviewed Kinase
Q9H4A3 BXGT020473 Serine/threonine-protein kinase WNK1 65125 reviewed Kinase
Q9HBX9 BXGT020523 Relaxin receptor 1 59350 reviewed G-protein coupled receptor
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NPH5 BXGT021159 NADPH oxidase 4 50507 reviewed Enzyme
Q9NQS5 BXGT021167 G-protein coupled receptor 84 53831 reviewed G-protein coupled receptor
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NRY4 BXGT021199 Rho GTPase-activating protein 35 2909 reviewed
Q9NS87 BXGT021201 Kinesin-like protein KIF15 56992 reviewed Cellular structure
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial 23410 reviewed Epigenetic regulator
Q9NYA1 BXGT021254 Sphingosine kinase 1 8877 reviewed Kinase
Q9NYK1 BXGT021258 Toll-like receptor 7 51284 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UBC3 BXGT021650 DNA (cytosine-5)-methyltransferase 3B 1789 reviewed
Q9UBN7 BXGT021658 Histone deacetylase 6 10013 reviewed Epigenetic regulator
Q9UHX3 BXGT021708 Adhesion G protein-coupled receptor E2 30817 reviewed G-protein coupled receptor
Q9UIK4 BXGT021720 Death-associated protein kinase 2 23604 reviewed Kinase
Q9UJU2 BXGT021730 Lymphoid enhancer-binding factor 1 51176 reviewed
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UNL4 BXGT021790 Inhibitor of growth protein 4 51147 reviewed Nucleic acid binding
Q9UNQ0 BXGT021792 ATP-binding cassette sub-family G member 2 9429 reviewed Transporter
Q9UPY3 BXGT021802 Endoribonuclease Dicer 23405 reviewed Enzyme
Q9Y2J8 BXGT022237 Protein-arginine deiminase type-2 11240 reviewed
Q9Y478 BXGT022271 5'-AMP-activated protein kinase subunit beta-1 5564 reviewed Kinase
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q9Y4P1 BXGT022283 Cysteine protease ATG4B 23192 reviewed Enzyme
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5Y6 BXGT022308 Suppressor of tumorigenicity 14 protein 6768 reviewed Enzyme
Q9Y6W6 BXGT022342 Dual specificity protein phosphatase 10 11221 reviewed
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q01995 BXGT022678 Transgelin 6876 reviewed Cellular structure
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P17535 BXGT023437 Transcription factor jun-D 3727 reviewed Transcription factor
P53539 BXGT023438 Protein fosB 2354 reviewed Transcription factor
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
P40198 BXGT023750 Carcinoembryonic antigen-related cell adhesion molecule 3 1084 reviewed
Q96QC4 BXGT023878 MHC class I polypeptide-related sequence A 100507436 unreviewed
Q9BQQ3 BXGT024065 Golgi reassembly-stacking protein 1 64689 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
Q14997 BXGT024710 Proteasome activator complex subunit 4 23198 reviewed
O43583 BXGT024866 Density-regulated protein 8562 reviewed Enzyme
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
P20809 BXGT025043 Interleukin-11 3589 reviewed
P51608 BXGT025073 Methyl-CpG-binding protein 2 4204 reviewed Epigenetic regulator
P25090 BXGT025102 N-formyl peptide receptor 2 2358 reviewed G-protein coupled receptor
Q9GZV5 BXGT025439 WW domain-containing transcription regulator protein 1 25937 reviewed Enzyme modulator
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q96Q15 BXGT025610 Serine/threonine-protein kinase SMG1 23049 reviewed Kinase
Q9NRR4 BXGT025788 Ribonuclease 3 29102 reviewed Enzyme
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P58215 BXGT026106 Lysyl oxidase homolog 3 84695 reviewed
Q9UBS0 BXGT026113 Ribosomal protein S6 kinase beta-2 6199 reviewed Kinase
Q96JB6 BXGT026118 Lysyl oxidase homolog 4 84171 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
V9HWB9 BXGT026149 L-lactate dehydrogenase 3939 unreviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease