Showing entry for Ghrelin O-acyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT019744
Protein NameGhrelin O-acyltransferase
Uniport IdQ96T53
GeneMBOAT4
Gene Id619373
DomainMBOAT
Pfam PF03062  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0030258 lipid modification
Biological Process GO:0018191 peptidyl-serine octanoylation
molecular function GO:0008374 O-acyltransferase activity
molecular function GO:0016412 serine O-acyltransferase activity
molecular function GO:0016746 transferase activity, transferring acyl groups
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0030176 integral component of endoplasmic reticulum membrane
cellular component GO:0016020 membrane
Reactome
Pathway Id Pathway Name
R-HSA-2980736 Peptide hormone metabolism
R-HSA-392499 Metabolism of proteins
R-HSA-422085 Synthesis, secretion, and deacylation of Ghrelin
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0003125 BXGD000179 Anorexia Nervosa Mental Disorders
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0011847 BXGD000749 Diabetes Endocrine System Diseases
C0011849 BXGD000751 Diabetes Mellitus Nutritional and Metabolic Diseases; Endocrine System Diseases
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0013473 BXGD000845 Eating Disorders Mental Disorders
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0041207 BXGD002898 Truncus Arteriosus, Persistent Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0042769 BXGD002999 Virus Diseases Infections
C0206754 BXGD004289 Neuroendocrine Tumors Neoplasms
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C2267227 BXGD017015 Bulimia Nervosa Mental Disorders
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0006362 Estrone 270.37
BXGC0014136 Cyclohex-2-En-1-One 96.06
BXGC0042842 Taraxerol 426.39
BXGC0042999 4-Cholesten 3-One 384.34
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein