adisease

Showing entry for Anxiety Disorders

General Disease Information
BXGD Id	BXGD000195
Disease Name	Anxiety Disorders
Disease CUI Id	C0003469
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00222	BXGT003899	Metabotropic glutamate receptor 8	2918	reviewed	G-protein coupled receptor
O00255	BXGT003903	Menin	4221	reviewed
O00408	BXGT003916	cGMP-dependent 3',5'-cyclic phosphodiesterase	5138	reviewed
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00748	BXGT003942	Cocaine esterase	8824	reviewed	Enzyme
O14578	BXGT004072	Citron Rho-interacting kinase	11113	reviewed	Kinase
O14618	BXGT004076	Copper chaperone for superoxide dismutase	9973	reviewed	Enzyme
O14994	BXGT004120	Synapsin-3	8224	reviewed	Cellular structure
O15054	BXGT004121	Lysine-specific demethylase 6B	23135	reviewed	Epigenetic regulator
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O15244	BXGT004140	Solute carrier family 22 member 2	6582	reviewed	Transporter
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O15350	BXGT004154	Tumor protein p73	7161	reviewed	Transcription factor
O43272	BXGT004580	Proline dehydrogenase 1, mitochondrial	5625	reviewed	Enzyme
O43603	BXGT004604	Galanin receptor type 2	8811	reviewed	G-protein coupled receptor
O43612	BXGT004605	Orexin	3060	reviewed
O43854	BXGT004630	EGF-like repeat and discoidin I-like domain-containing protein 3	10085	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60674	BXGT004892	Tyrosine-protein kinase JAK2	3717	reviewed	Kinase
O60741	BXGT004897	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1	348980	reviewed
O60755	BXGT004898	Galanin receptor type 3	8484	reviewed	G-protein coupled receptor
O60760	BXGT004899	Hematopoietic prostaglandin D synthase	27306	reviewed
O75369	BXGT005119	Filamin-B	2317	reviewed
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O75628	BXGT005140	GTP-binding protein REM 1	28954	reviewed
O76054	BXGT005172	SEC14-like protein 2	23541	reviewed
O94759	BXGT005327	Transient receptor potential cation channel subfamily M member 2	7226	reviewed	Ion channel
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95398	BXGT005378	Rap guanine nucleotide exchange factor 3	10411	reviewed	Enzyme modulator
O95639	BXGT005388	Cleavage and polyadenylation specificity factor subunit 4	10898	reviewed	Enzyme
O95831	BXGT005399	Apoptosis-inducing factor 1, mitochondrial	9131	reviewed	Enzyme
P00325	BXGT005498	Alcohol dehydrogenase 1B	125	reviewed	Enzyme
P00352	BXGT005510	Retinal dehydrogenase 1	216	reviewed	Enzyme
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00740	BXGT005634	Coagulation factor IX	2158	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01009	BXGT005714	Alpha-1-antitrypsin	5265	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01100	BXGT005727	Proto-oncogene c-Fos	2353	reviewed	Transcription factor
P01111	BXGT005731	GTPase NRas	4893	reviewed	Enzyme modulator
P01112	BXGT005732	GTPase HRas	3265	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02724	BXGT005934	Glycophorin-A	2993	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03891	BXGT006110	NADH-ubiquinone oxidoreductase chain 2	4536	reviewed
P03923	BXGT006115	NADH-ubiquinone oxidoreductase chain 6	4541	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04745	BXGT006255	Alpha-amylase 1	278	reviewed
P04818	BXGT006269	Thymidylate synthase	7298	reviewed	Enzyme
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05091	BXGT006312	Aldehyde dehydrogenase, mitochondrial	217	reviewed	Enzyme
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05120	BXGT006319	Plasminogen activator inhibitor 2	5055	reviewed	Enzyme modulator
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05154	BXGT006327	Plasma serine protease inhibitor	5104	reviewed	Enzyme modulator
P05155	BXGT006328	Plasma protease C1 inhibitor	710	reviewed	Enzyme modulator
P05156	BXGT006329	Complement factor I	3426	reviewed
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05177	BXGT006336	Cytochrome P450 1A2	1544	reviewed	Enzyme
P05181	BXGT006337	Cytochrome P450 2E1	1571	reviewed
P05186	BXGT006338	Alkaline phosphatase, tissue-nonspecific isozyme	249	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06276	BXGT006430	Cholinesterase	590	reviewed
P06454	BXGT006441	Prothymosin alpha	5757	reviewed
P06730	BXGT006487	Eukaryotic translation initiation factor 4E	1977	reviewed	Nucleic acid binding
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P07108	BXGT006551	Acyl-CoA-binding protein	1622	reviewed	Enzyme modulator
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P07237	BXGT006576	Protein disulfide-isomerase	5034	reviewed
P07288	BXGT006591	Prostate-specific antigen	354	reviewed	Enzyme
P07332	BXGT006601	Tyrosine-protein kinase Fes/Fps	2242	reviewed	Kinase
P07333	BXGT006602	Macrophage colony-stimulating factor 1 receptor	1436	reviewed	Kinase
P07384	BXGT006619	Calpain-1 catalytic subunit	823	reviewed	Enzyme
P07550	BXGT006636	Beta-2 adrenergic receptor	154	reviewed	G-protein coupled receptor
P07814	BXGT006680	Bifunctional glutamate/proline--tRNA ligase	2058	reviewed	Enzyme
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08235	BXGT006751	Mineralocorticoid receptor	4306	reviewed	Nuclear receptor
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	3350	reviewed	G-protein coupled receptor
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09172	BXGT006865	Dopamine beta-hydroxylase	1621	reviewed
P09211	BXGT006869	Glutathione S-transferase P	2950	reviewed
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P0DP23	BXGT007520	Calmodulin-1	808	reviewed
P0DP24	BXGT007521	Calmodulin-2	808	reviewed
P10070	BXGT007534	Zinc finger protein GLI2	2736	reviewed
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10275	BXGT007552	Androgen receptor	367	reviewed	Nuclear receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10635	BXGT007595	Cytochrome P450 2D6	1565	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P11498	BXGT007714	Pyruvate carboxylase, mitochondrial	5091	reviewed	Enzyme
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	6714	reviewed	Kinase
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13716	BXGT007948	Delta-aminolevulinic acid dehydratase	210	reviewed	Enzyme
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P14324	BXGT008005	Farnesyl pyrophosphate synthase	2224	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14616	BXGT008026	Insulin receptor-related protein	3645	reviewed	Kinase
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P14902	BXGT008065	Indoleamine 2,3-dioxygenase 1	3620	reviewed
P14920	BXGT008067	D-amino-acid oxidase	1610	reviewed
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16083	BXGT008187	Ribosyldihydronicotinamide dehydrogenase [quinone]	4835	reviewed
P16220	BXGT008206	Cyclic AMP-responsive element-binding protein 1	1385	reviewed
P17405	BXGT008304	Sphingomyelin phosphodiesterase	6609	reviewed	Enzyme
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	262	reviewed	Enzyme
P17787	BXGT008341	Neuronal acetylcholine receptor subunit beta-2	1141	reviewed	Ion channel
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P17936	BXGT008357	Insulin-like growth factor-binding protein 3	3486	reviewed	Enzyme modulator
P18031	BXGT008369	Tyrosine-protein phosphatase non-receptor type 1	5770	reviewed
P18089	BXGT008379	Alpha-2B adrenergic receptor	151	reviewed	G-protein coupled receptor
P18405	BXGT008400	3-oxo-5-alpha-steroid 4-dehydrogenase 1	6715	reviewed	Enzyme
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	2566	reviewed	Ion channel
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20061	BXGT008542	Transcobalamin-1	6947	reviewed
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20711	BXGT008594	Aromatic-L-amino-acid decarboxylase	1644	reviewed
P20810	BXGT008602	Calpastatin	831	reviewed
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21333	BXGT008638	Filamin-A	2316	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21580	BXGT008666	Tumor necrosis factor alpha-induced protein 3	7128	reviewed	Enzyme
P21589	BXGT008669	5'-nucleotidase	4907	reviewed	Enzyme
P21673	BXGT008676	Diamine acetyltransferase 1	6303	reviewed
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P22749	BXGT008803	Granulysin	10578	reviewed
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24387	BXGT008966	Corticotropin-releasing factor-binding protein	1393	reviewed	Signaling
P25101	BXGT009018	Endothelin-1 receptor	1909	reviewed	G-protein coupled receptor
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P25929	BXGT009078	Neuropeptide Y receptor type 1	4886	reviewed	G-protein coupled receptor
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27338	BXGT009172	Amine oxidase [flavin-containing] B	4129	reviewed
P27352	BXGT009174	Cobalamin binding intrinsic factor	2694	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27815	BXGT009208	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	5141	reviewed
P28039	BXGT009224	Acyloxyacyl hydrolase	313	reviewed
P28072	BXGT009231	Proteasome subunit beta type-6	5694	reviewed
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29033	BXGT009308	Gap junction beta-2 protein	2706	reviewed	Cell-cell junction
P29274	BXGT009327	Adenosine receptor A2a	135	reviewed	G-protein coupled receptor
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29475	BXGT009353	Nitric oxide synthase, brain	4842	reviewed
P30531	BXGT009432	Sodium- and chloride-dependent GABA transporter 1	6529	reviewed	Transporter
P30532	BXGT009433	Neuronal acetylcholine receptor subunit alpha-5	1138	reviewed	Ion channel
P30536	BXGT009435	Translocator protein	706	reviewed
P30542	BXGT009436	Adenosine receptor A1	134	reviewed	G-protein coupled receptor
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P31391	BXGT009535	Somatostatin receptor type 4	6754	reviewed	G-protein coupled receptor
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	2558	reviewed	Ion channel
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P32238	BXGT009611	Cholecystokinin receptor type A	886	reviewed	G-protein coupled receptor
P32239	BXGT009612	Gastrin/cholecystokinin type B receptor	887	reviewed	G-protein coupled receptor
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P33261	BXGT009707	Cytochrome P450 2C19	1557	reviewed
P34059	BXGT009749	N-acetylgalactosamine-6-sulfatase	2588	reviewed	Enzyme
P34949	BXGT009775	Mannose-6-phosphate isomerase	4351	reviewed	Enzyme
P34969	BXGT009777	5-hydroxytryptamine receptor 7	3363	reviewed	G-protein coupled receptor
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35348	BXGT009814	Alpha-1A adrenergic receptor	148	reviewed	G-protein coupled receptor
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35372	BXGT009823	Mu-type opioid receptor	4988	reviewed	G-protein coupled receptor
P35398	BXGT009825	Nuclear receptor ROR-alpha	6095	reviewed	Nuclear receptor
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P35498	BXGT009838	Sodium channel protein type 1 subunit alpha	6323	reviewed	Ion channel
P35555	BXGT009845	Fibrillin-1	2200	reviewed	Calcium-binding protein
P35579	BXGT009852	Myosin-9	4627	reviewed
P35916	BXGT009881	Vascular endothelial growth factor receptor 3	2324	reviewed	Kinase
P36969	BXGT009949	Phospholipid hydroperoxide glutathione peroxidase	2879	reviewed	Enzyme
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37288	BXGT009977	Vasopressin V1a receptor	552	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P38571	BXGT010054	Lysosomal acid lipase/cholesteryl ester hydrolase	3988	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P39086	BXGT010093	Glutamate receptor ionotropic, kainate 1	2897	reviewed	Ion channel
P39900	BXGT010148	Macrophage metalloelastase	4321	reviewed	Enzyme
P40337	BXGT010174	von Hippel-Lindau disease tumor suppressor	7428	reviewed	Enzyme
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P41145	BXGT010225	Kappa-type opioid receptor	4986	reviewed	G-protein coupled receptor
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P41597	BXGT010268	C-C chemokine receptor type 2	729230	reviewed
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P42262	BXGT010294	Glutamate receptor 2	2891	reviewed	Ion channel
P42330	BXGT010301	Aldo-keto reductase family 1 member C3	8644	reviewed	Enzyme
P42575	BXGT010318	Caspase-2	835	reviewed	Enzyme
P42858	BXGT010341	Huntingtin	3064	reviewed
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43004	BXGT010348	Excitatory amino acid transporter 2	6506	reviewed	Transporter
P43005	BXGT010349	Excitatory amino acid transporter 3	6505	reviewed	Transporter
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	2555	reviewed	Ion channel
P47901	BXGT010596	Vasopressin V1b receptor	553	reviewed	G-protein coupled receptor
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48147	BXGT010620	Prolyl endopeptidase	5550	reviewed	Enzyme
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49146	BXGT010681	Neuropeptide Y receptor type 2	4887	reviewed	G-protein coupled receptor
P49585	BXGT010712	Choline-phosphate cytidylyltransferase A	5130	reviewed
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49903	BXGT010759	Selenide, water dikinase 1	22929	reviewed	Enzyme
P50052	BXGT010768	Type-2 angiotensin II receptor	186	reviewed	G-protein coupled receptor
P50406	BXGT010796	5-hydroxytryptamine receptor 6	3362	reviewed	G-protein coupled receptor
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51687	BXGT010882	Sulfite oxidase, mitochondrial	6821	reviewed
P52758	BXGT010951	2-iminobutanoate/2-iminopropanoate deaminase	10247	reviewed
P52788	BXGT010953	Spermine synthase	6611	reviewed
P54756	BXGT011074	Ephrin type-A receptor 5	2044	reviewed	Kinase
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P54855	BXGT011088	UDP-glucuronosyltransferase 2B15	7366	reviewed
P55055	BXGT011101	Oxysterols receptor LXR-beta	7376	reviewed	Nuclear receptor
P55786	BXGT011125	Puromycin-sensitive aminopeptidase	9520	reviewed	Enzyme
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60903	BXGT011339	Protein S100-A10	6281	reviewed	Calcium-binding protein
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P62166	BXGT011412	Neuronal calcium sensor 1	23413	reviewed
P62258	BXGT011415	14-3-3 protein epsilon	7531	reviewed	Chaperone
P63000	BXGT011481	Ras-related C3 botulinum toxin substrate 1	5879	reviewed	Enzyme modulator
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	2778	reviewed
P78330	BXGT011833	Phosphoserine phosphatase	5723	reviewed	Enzyme
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
P80404	BXGT011907	4-aminobutyrate aminotransferase, mitochondrial	18	reviewed	Enzyme
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q00653	BXGT012541	Nuclear factor NF-kappa-B p100 subunit	4791	reviewed	Transcription factor
Q01105	BXGT012569	Protein SET	6418	reviewed	Enzyme modulator
Q01538	BXGT012597	Myelin transcription factor 1	4661	reviewed	Transcription factor
Q01726	BXGT012610	Melanocyte-stimulating hormone receptor	4157	reviewed	G-protein coupled receptor
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q04609	BXGT012768	Glutamate carboxypeptidase 2	2346	reviewed	Enzyme
Q04760	BXGT012782	Lactoylglutathione lyase	2739	reviewed
Q04828	BXGT012787	Aldo-keto reductase family 1 member C1	1645	reviewed	Enzyme
Q05329	BXGT012814	Glutamate decarboxylase 2	2572	reviewed	Enzyme
Q05940	BXGT012846	Synaptic vesicular amine transporter	6571	reviewed	Transporter
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q06787	BXGT012890	Synaptic functional regulator FMR1	2332	reviewed	Nucleic acid binding
Q07075	BXGT012917	Glutamyl aminopeptidase	2028	reviewed	Enzyme
Q07343	BXGT012926	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	5142	reviewed
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q09472	BXGT013038	Histone acetyltransferase p300	2033	reviewed
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13163	BXGT013321	Dual specificity mitogen-activated protein kinase kinase 5	5607	reviewed	Kinase
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13324	BXGT013340	Corticotropin-releasing factor receptor 2	1395	reviewed	G-protein coupled receptor
Q13451	BXGT013356	Peptidyl-prolyl cis-trans isomerase FKBP5	2289	reviewed	Enzyme
Q13541	BXGT013371	Eukaryotic translation initiation factor 4E-binding protein 1	1978	reviewed	Nucleic acid binding
Q13555	BXGT013375	Calcium/calmodulin-dependent protein kinase type II subunit gamma	818	reviewed	Kinase
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14164	BXGT013451	Inhibitor of nuclear factor kappa-B kinase subunit epsilon	9641	reviewed	Kinase
Q14469	BXGT013473	Transcription factor HES-1	3280	reviewed	Transcription factor
Q15020	BXGT013522	Squamous cell carcinoma antigen recognized by T-cells 3	9733	reviewed	Nucleic acid binding
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15761	BXGT013596	Neuropeptide Y receptor type 5	4889	reviewed	G-protein coupled receptor
Q15822	BXGT013602	Neuronal acetylcholine receptor subunit alpha-2	1135	reviewed	Ion channel
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	2559	reviewed	Ion channel
Q16555	BXGT013638	Dihydropyrimidinase-related protein 2	1808	reviewed	Enzyme
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16674	BXGT013655	Melanoma-derived growth regulatory protein	8190	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q5VZ30	BXGT015894	Glutamate decarboxylase 2 (Pancreatic islets and brain, 65kDa)	2572	unreviewed
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6W5P4	BXGT016588	Neuropeptide S receptor	387129	reviewed
Q7KZF4	BXGT016989	Staphylococcal nuclease domain-containing protein 1	27044	reviewed	Transcription factor
Q7LBC6	BXGT016998	Lysine-specific demethylase 3B	51780	reviewed	Epigenetic regulator
Q8IVA8	BXGT018342	Glutamate decarboxylase 1 (Brain, 67kDa)	2571	unreviewed
Q8N6T7	BXGT018525	NAD-dependent protein deacetylase sirtuin-6	51548	reviewed	Epigenetic regulator
Q8NER1	BXGT018556	Transient receptor potential cation channel subfamily V member 1	7442	reviewed	Ion channel
Q8NFD2	BXGT018559	Ankyrin repeat and protein kinase domain-containing protein 1	255239	reviewed	Kinase
Q8WXD9	BXGT019010	Caskin-1	57524	reviewed	Receptor
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q8WZA2	BXGT019025	Rap guanine nucleotide exchange factor 4	11069	reviewed	Enzyme modulator
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q96C19	BXGT019630	EF-hand domain-containing protein D2	79180	reviewed	Calcium-binding protein
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96EN8	BXGT019649	Molybdenum cofactor sulfurase	55034	reviewed
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PF2	BXGT019708	Testis-specific serine/threonine-protein kinase 2	23617	reviewed	Kinase
Q96RJ0	BXGT019728	Trace amine-associated receptor 1	134864	reviewed	G-protein coupled receptor
Q96RR4	BXGT019734	Calcium/calmodulin-dependent protein kinase kinase 2	10645	reviewed	Kinase
Q96T53	BXGT019744	Ghrelin O-acyltransferase	619373	reviewed
Q99259	BXGT019915	Glutamate decarboxylase 1	2571	reviewed	Enzyme
Q99497	BXGT019926	Protein/nucleic acid deglycase DJ-1	11315	reviewed	Enzyme
Q99527	BXGT019930	G-protein coupled estrogen receptor 1	2852	reviewed	G-protein coupled receptor
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99623	BXGT019941	Prohibitin-2	11331	reviewed
Q99685	BXGT019948	Monoglyceride lipase	11343	reviewed	Enzyme
Q99705	BXGT019951	Melanin-concentrating hormone receptor 1	2847	reviewed	G-protein coupled receptor
Q99720	BXGT019955	Sigma non-opioid intracellular receptor 1	10280	reviewed
Q99836	BXGT019970	Myeloid differentiation primary response protein MyD88	4615	reviewed	Enzyme modulator
Q9BS40	BXGT020121	Latexin	56925	reviewed
Q9BUB5	BXGT020133	MAP kinase-interacting serine/threonine-protein kinase 1	8569	reviewed	Kinase
Q9BXA7	BXGT020164	Testis-specific serine/threonine-protein kinase 1	83942	reviewed	Kinase
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9BY08	BXGT020177	Emopamil-binding protein-like	84650	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NP56	BXGT021142	cAMP-specific 3',5'-cyclic phosphodiesterase 7B	27115	reviewed
Q9NQX3	BXGT021172	Gephyrin	10243	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRW3	BXGT021195	DNA dC->dU-editing enzyme APOBEC-3C	27350	reviewed	Enzyme
Q9NSD7	BXGT021205	Relaxin-3 receptor 1	51289	reviewed	G-protein coupled receptor
Q9NXG6	BXGT021246	Transmembrane prolyl 4-hydroxylase	54681	reviewed
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9P2W7	BXGT021306	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1	27087	reviewed	Enzyme
Q9UBB5	BXGT021649	Methyl-CpG-binding domain protein 2	8932	reviewed	Epigenetic regulator
Q9UBC3	BXGT021650	DNA (cytosine-5)-methyltransferase 3B	1789	reviewed
Q9UJU2	BXGT021730	Lymphoid enhancer-binding factor 1	51176	reviewed
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UL54	BXGT021755	Serine/threonine-protein kinase TAO2	9344	reviewed	Kinase
Q9ULC6	BXGT021759	Protein-arginine deiminase type-1	29943	reviewed
Q9ULW0	BXGT021766	Targeting protein for Xklp2	22974	reviewed	Cellular structure
Q9UN36	BXGT021780	Protein NDRG2	57447	reviewed	Enzyme
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	55879	reviewed	Ion channel
Q9UPP1	BXGT021800	Histone lysine demethylase PHF8	23133	reviewed
Q9Y219	BXGT022206	Protein jagged-2	3714	reviewed
Q9Y233	BXGT022210	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	10846	reviewed
Q9Y251	BXGT022215	Heparanase	10855	reviewed	Enzyme
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
Q9Y2T6	BXGT022247	G-protein coupled receptor 55	9290	reviewed	G-protein coupled receptor
Q9Y2W7	BXGT022250	Calsenilin	30818	reviewed	Ion channel
Q9Y3I1	BXGT022260	F-box only protein 7	25793	reviewed
Q9Y3Q4	BXGT022264	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4	10021	reviewed	Ion channel
Q9Y617	BXGT022314	Phosphoserine aminotransferase	29968	reviewed
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	10599	reviewed	Transporter
Q9H2H9	BXGT022646	Sodium-coupled neutral amino acid transporter 1	81539	reviewed	Transporter
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
P35240	BXGT022927	Merlin	4771	reviewed
O75976	BXGT022954	Carboxypeptidase D	1362	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P17752	BXGT023118	Tryptophan 5-hydroxylase 1	7166	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q63ZY3	BXGT023544	KN motif and ankyrin repeat domain-containing protein 2	25959	reviewed
Q86Y78	BXGT024070	Ly6/PLAUR domain-containing protein 6	130574	reviewed
P0DP25	BXGT024595	Calmodulin-3	808	reviewed
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
Q96A54	BXGT024681	Adiponectin receptor protein 1	51094	reviewed	Receptor
Q14807	BXGT024966	Kinesin-like protein KIF22	3835	reviewed	Cellular structure
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
P27918	BXGT025485	Properdin	5199	reviewed
O43613	BXGT025666	Orexin receptor type 1	3061	reviewed	G-protein coupled receptor
Q96C45	BXGT025705	Serine/threonine-protein kinase ULK4	54986	reviewed	Kinase
Q96RD7	BXGT025890	Pannexin-1	24145	reviewed	Ion channel
Q96SD1	BXGT025929	Protein artemis	64421	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}