adisease

Showing entry for Anorexia Nervosa

General Disease Information
BXGD Id	BXGD000179
Disease Name	Anorexia Nervosa
Disease CUI Id	C0003125
MeSH Codes	F03
Disease Class Name	Mental Disorders
Semantic Type	Mental or Behavioral Dysfunction
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:150
Disease Ontology Class Name	disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O60271	BXGT004866	C-Jun-amino-terminal kinase-interacting protein 4	9043	reviewed	Enzyme modulator
O95264	BXGT005367	5-hydroxytryptamine receptor 3B	9177	reviewed	Ion channel
O95390	BXGT005377	Growth/differentiation factor 11	10220	reviewed	Signaling
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01270	BXGT005746	Parathyroid hormone	5741	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04150	BXGT006154	Glucocorticoid receptor	2908	reviewed	Nuclear receptor
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04745	BXGT006255	Alpha-amylase 1	278	reviewed
P05093	BXGT006313	Steroid 17-alpha-hydroxylase/17,20 lyase	1586	reviewed
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07108	BXGT006551	Acyl-CoA-binding protein	1622	reviewed	Enzyme modulator
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08833	BXGT006827	Insulin-like growth factor-binding protein 1	3484	reviewed	Enzyme modulator
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15169	BXGT008093	Carboxypeptidase N catalytic chain	1369	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P20813	BXGT008603	Cytochrome P450 2B6	1555	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21554	BXGT008662	Cannabinoid receptor 1	1268	reviewed	G-protein coupled receptor
P21917	BXGT008707	D(4) dopamine receptor	1815	reviewed	G-protein coupled receptor
P21964	BXGT008714	Catechol O-methyltransferase	1312	reviewed	Enzyme
P22792	BXGT008807	Carboxypeptidase N subunit 2	1370	reviewed	Receptor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P23975	BXGT008935	Sodium-dependent noradrenaline transporter	6530	reviewed	Transporter
P24298	BXGT008960	Alanine aminotransferase 1	2875	reviewed	Enzyme
P24864	BXGT009000	G1/S-specific cyclin-E1	898	reviewed	Enzyme modulator
P25103	BXGT009020	Substance-P receptor	6869	reviewed	G-protein coupled receptor
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28072	BXGT009231	Proteasome subunit beta type-6	5694	reviewed
P28221	BXGT009237	5-hydroxytryptamine receptor 1D	3352	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28335	BXGT009255	5-hydroxytryptamine receptor 2C	3358	reviewed	G-protein coupled receptor
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30559	BXGT009442	Oxytocin receptor	5021	reviewed	G-protein coupled receptor
P31645	BXGT009558	Sodium-dependent serotonin transporter	6532	reviewed	Transporter
P32238	BXGT009611	Cholecystokinin receptor type A	886	reviewed	G-protein coupled receptor
P32245	BXGT009614	Melanocortin receptor 4	4160	reviewed	G-protein coupled receptor
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	2053	reviewed	Enzyme
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35462	BXGT009835	D(3) dopamine receptor	1814	reviewed	G-protein coupled receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40933	BXGT010209	Interleukin-15	3600	reviewed
P41143	BXGT010223	Delta-type opioid receptor	4985	reviewed	G-protein coupled receptor
P41968	BXGT010275	Melanocortin receptor 3	4159	reviewed	G-protein coupled receptor
P42263	BXGT010295	Glutamate receptor 3	2892	reviewed	Ion channel
P46098	BXGT010507	5-hydroxytryptamine receptor 3A	3359	reviewed	Ion channel
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P48357	BXGT010627	Leptin receptor	3953	reviewed	Signaling
P51688	BXGT010883	N-sulphoglucosamine sulphohydrolase	6448	reviewed	Enzyme
P54219	BXGT011037	Chromaffin granule amine transporter	6570	reviewed	Transporter
P54762	BXGT011076	Ephrin type-B receptor 1	2047	reviewed	Kinase
P55789	BXGT011126	FAD-linked sulfhydryl oxidase ALR	2671	reviewed	Enzyme
P56524	BXGT011176	Histone deacetylase 4	9759	reviewed	Epigenetic regulator
P56545	BXGT011178	C-terminal-binding protein 2	1488	reviewed	Transcription factor
P61626	BXGT011382	Lysozyme C	4069	reviewed
P62826	BXGT011463	GTP-binding nuclear protein Ran	5901	reviewed	Enzyme modulator
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07820	BXGT012942	Induced myeloid leukemia cell differentiation protein Mcl-1	4170	reviewed	Signaling
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q13133	BXGT013315	Oxysterols receptor LXR-alpha	10062	reviewed	Nuclear receptor
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13427	BXGT013354	Peptidyl-prolyl cis-trans isomerase G	9360	reviewed
Q13639	BXGT013389	5-hydroxytryptamine receptor 4	3360	reviewed	G-protein coupled receptor
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16288	BXGT013625	NT-3 growth factor receptor	4916	reviewed	Kinase
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q2MKA7	BXGT014140	R-spondin-1	284654	reviewed
Q59FK2	BXGT015276	Selenocysteine lyase variant	51540	unreviewed
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q96I15	BXGT019674	Selenocysteine lyase	51540	reviewed	Enzyme
Q96T53	BXGT019744	Ghrelin O-acyltransferase	619373	reviewed
Q9BZ23	BXGT020194	Pantothenate kinase 2, mitochondrial	80025	reviewed	Kinase
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9UGI6	BXGT021681	Small conductance calcium-activated potassium channel protein 3	3782	reviewed	Ion channel
Q9Y2I2	BXGT022236	Netrin-G1	22854	reviewed	Enzyme modulator
Q9Y2T6	BXGT022247	G-protein coupled receptor 55	9290	reviewed	G-protein coupled receptor
Q92847	BXGT022673	Growth hormone secretagogue receptor type 1	2693	reviewed	G-protein coupled receptor
O14793	BXGT023280	Growth/differentiation factor 8	2660	reviewed	Signaling
Q9BY76	BXGT025687	Angiopoietin-related protein 4	51129	reviewed	Signaling
Q8NI99	BXGT025986	Angiopoietin-related protein 6	83854	reviewed	Signaling
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme
P07320	BXGT026150	Gamma-crystallin D	1421	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}