Showing entry for Tyrosine-protein phosphatase non-receptor type 23


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT020467
Protein NameTyrosine-protein phosphatase non-receptor type 23
Uniport IdQ9H3S7
GenePTPN23
Gene Id25930
DomainALIX_LYPXL_bnd; BRO1; Y_phosphatase
Pfam PF13949   PF03097   PF00102  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0071345 cellular response to cytokine stimulus
Biological Process GO:0060271 cilium assembly
Biological Process GO:0045022 early endosome to late endosome transport
Biological Process GO:0032456 endocytic recycling
Biological Process GO:0010633 negative regulation of epithelial cell migration
Biological Process GO:1903393 positive regulation of adherens junction organization
Biological Process GO:2000643 positive regulation of early endosome to late endosome transport
Biological Process GO:1903387 positive regulation of homophilic cell adhesion
Biological Process GO:0061357 positive regulation of Wnt protein secretion
Biological Process GO:0015031 protein transport
Biological Process GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
molecular function GO:0019901 protein kinase binding
molecular function GO:0004725 protein tyrosine phosphatase activity
cellular component GO:0036064 ciliary basal body
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0016604 nuclear body
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-168256 Immune System
R-HSA-446652 Interleukin-1 family signaling
R-HSA-449147 Signaling by Interleukins
R-HSA-9008059 Interleukin-37 signaling
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0011860 BXGD000755 Diabetes Mellitus, Non-Insulin-Dependent Nutritional and Metabolic Diseases; Endocrine System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0027092 BXGD001971 Myopia Eye Diseases
C0027651 BXGD002009 Neoplasms Neoplasms
C0036202 BXGD002581 Sarcoidosis Hemic and Lymphatic Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0205851 BXGD004132 Germ cell tumor Neoplasms
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0345964 BXGD007755 Adenoma of lung Neoplasms
C0543888 BXGD009300 Epileptic encephalopathy Nervous System Diseases
C0557874 BXGD009444 Global developmental delay
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3854222 BXGD019826 Human immunodeficiency virus (HIV) II infection category B1
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
BXGC0049447 acetate 59.01
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein