Showing entry for Sialic acid-binding Ig-like lectin 8


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021265
Protein NameSialic acid-binding Ig-like lectin 8
Uniport IdQ9NYZ4
GeneSIGLEC8
Gene Id27181
DomainV-set
Pfam PF07686  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0007155 cell adhesion
Biological Process GO:0007165 signal transduction
molecular function GO:0030246 carbohydrate binding
molecular function GO:0033691 sialic acid binding
molecular function GO:0004888 transmembrane signaling receptor activity
cellular component GO:0016021 integral component of membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-1280218 Adaptive Immune System
R-HSA-168256 Immune System
R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0014458 BXGD000916 Eosinophilia, Tropical Hemic and Lymphatic Diseases
C0017152 BXGD001096 Gastritis Digestive System Diseases
C0017160 BXGD001099 Gastroenteritis Digestive System Diseases
C0019569 BXGD001337 Hirschsprung Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases
C0023461 BXGD001653 Leukemia, Mast-Cell Neoplasms
C0024117 BXGD001734 Chronic Obstructive Airway Disease Respiratory Tract Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0032285 BXGD002344 Pneumonia Infections; Respiratory Tract Diseases
C0034068 BXGD002457 Pulmonary Eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0040580 BXGD002877 Tracheal Diseases Respiratory Tract Diseases
C0155877 BXGD003830 Allergic asthma Respiratory Tract Diseases; Immune System Diseases
C0263338 BXGD005290 Chronic urticaria Skin and Connective Tissue Diseases; Immune System Diseases
C0279702 BXGD006685 Conventional (Clear Cell) Renal Cell Carcinoma Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0340076 BXGD007302 Asthmatic pulmonary eosinophilia Respiratory Tract Diseases; Hemic and Lymphatic Diseases
C0341106 BXGD007389 Eosinophilic esophagitis Digestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
C0346421 BXGD007827 Chronic eosinophilic leukemia Neoplasms; Hemic and Lymphatic Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0494463 BXGD009029 Alzheimer Disease, Late Onset Nervous System Diseases; Mental Disorders
C1262481 BXGD011883 Eosinophilic gastroenteritis Digestive System Diseases; Hemic and Lymphatic Diseases
C1306759 BXGD012374 Eosinophilic disorder Hemic and Lymphatic Diseases
C3714636 BXGD019421 Pneumonitis Infections; Respiratory Tract Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003614 Propanolamine 75.11
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein