Showing entry for Eosinophilic esophagitis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD007389
Disease NameEosinophilic esophagitis
Disease CUI IdC0341106
MeSH Codes C06   C20   C15  
Disease Class NameDigestive System Diseases; Immune System Diseases; Hemic and Lymphatic Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14843 BXGT004107 Free fatty acid receptor 3 2865 reviewed G-protein coupled receptor
O15455 BXGT004171 Toll-like receptor 3 7098 reviewed Receptor
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60271 BXGT004866 C-Jun-amino-terminal kinase-interacting protein 4 9043 reviewed Enzyme modulator
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 8856 reviewed Nuclear receptor
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
P00709 BXGT005621 Alpha-lactalbumin 3906 reviewed
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08758 BXGT006821 Annexin A5 308 reviewed
P09848 BXGT006929 Lactase-phlorizin hydrolase 3938 reviewed Enzyme
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10153 BXGT007544 Non-secretory ribonuclease 6036 reviewed
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11678 BXGT007736 Eosinophil peroxidase 8288 reviewed Enzyme
P12724 BXGT007837 Eosinophil cationic protein 6037 reviewed
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13727 BXGT007951 Bone marrow proteoglycan 5553 reviewed Enzyme modulator
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P16050 BXGT008184 Arachidonate 15-lipoxygenase 246 reviewed Enzyme
P16070 BXGT008186 CD44 antigen 960 reviewed
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19883 BXGT008528 Follistatin 10468 reviewed Enzyme modulator
P20930 BXGT008616 Filaggrin 2312 reviewed Cellular structure
P20933 BXGT008618 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase 175 reviewed Enzyme
P21549 BXGT008661 Serine--pyruvate aminotransferase 189 reviewed Enzyme
P21583 BXGT008667 Kit ligand 4254 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29372 BXGT009336 DNA-3-methyladenine glycosylase 4350 reviewed Enzyme
P29597 BXGT009367 Non-receptor tyrosine-protein kinase TYK2 7297 reviewed Kinase
P31151 BXGT009510 Protein S100-A7 6278 reviewed Calcium-binding protein
P31997 BXGT009593 Carcinoembryonic antigen-related cell adhesion molecule 8 1088 reviewed
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P40933 BXGT010209 Interleukin-15 3600 reviewed
P41594 BXGT010266 Metabotropic glutamate receptor 5 2915 reviewed G-protein coupled receptor
P42224 BXGT010286 Signal transducer and activator of transcription 1-alpha/beta 6772 reviewed Nucleic acid binding
P42226 BXGT010288 Signal transducer and activator of transcription 6 6778 reviewed Nucleic acid binding
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P49862 BXGT010752 Kallikrein-7 5650 reviewed Enzyme
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P50281 BXGT010788 Matrix metalloproteinase-14 4323 reviewed Enzyme
P50591 BXGT010814 Tumor necrosis factor ligand superfamily member 10 8743 reviewed Signaling
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P51688 BXGT010883 N-sulphoglucosamine sulphohydrolase 6448 reviewed Enzyme
P54707 BXGT011068 Potassium-transporting ATPase alpha chain 2 479 reviewed Transporter
P55085 BXGT011104 Proteinase-activated receptor 2 2150 reviewed G-protein coupled receptor
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P55957 BXGT011137 BH3-interacting domain death agonist 637 reviewed
Q01344 BXGT012585 Interleukin-5 receptor subunit alpha 3568 reviewed Signaling
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q05193 BXGT012810 Dynamin-1 1759 reviewed Enzyme modulator
Q05315 BXGT012811 Galectin-10 1178 reviewed Signaling
Q07912 BXGT012947 Activated CDC42 kinase 1 10188 reviewed Kinase
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q13478 BXGT013362 Interleukin-18 receptor 1 8809 reviewed Receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14392 BXGT013465 Transforming growth factor beta activator LRRC32 2615 reviewed Receptor
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15257 BXGT013554 Serine/threonine-protein phosphatase 2A activator 5524 reviewed Enzyme modulator
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q16873 BXGT013684 Leukotriene C4 synthase 4056 reviewed Enzyme
Q8NER1 BXGT018556 Transient receptor potential cation channel subfamily V member 1 7442 reviewed Ion channel
Q92731 BXGT019366 Estrogen receptor beta 2100 reviewed Nuclear receptor
Q92876 BXGT019388 Kallikrein-6 5653 reviewed Enzyme
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 1244 reviewed Transporter
Q92956 BXGT019399 Tumor necrosis factor receptor superfamily member 14 8764 reviewed
Q9BZ23 BXGT020194 Pantothenate kinase 2, mitochondrial 80025 reviewed Kinase
Q9BZP6 BXGT020201 Acidic mammalian chitinase 27159 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NYZ4 BXGT021265 Sialic acid-binding Ig-like lectin 8 27181 reviewed Receptor
Q9UI42 BXGT021713 Carboxypeptidase A4 51200 reviewed Enzyme
Q9UKU7 BXGT021749 Isobutyryl-CoA dehydrogenase, mitochondrial 27034 reviewed Enzyme
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
Q14186 BXGT023367 Transcription factor Dp-1 7027 reviewed Nucleic acid binding
Q96HY7 BXGT025609 Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial 55526 reviewed
Q8N573 BXGT026157 Oxidation resistance protein 1 55074 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease