Showing entry for Large neutral amino acids transporter small subunit 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021700
Protein NameLarge neutral amino acids transporter small subunit 2
Uniport IdQ9UHI5
GeneSLC7A8
Gene Id23428
Domain_permease_2
Pfam PF13520  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
5. Organismal Systems 5.4 Digestive system hsa04974 Protein digestion and absorption
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0089718 amino acid import across plasma membrane
Biological Process GO:0006865 amino acid transport
Biological Process GO:0015816 glycine transport
Biological Process GO:1904273 L-alanine import across plasma membrane
Biological Process GO:0098713 leucine import across plasma membrane
Biological Process GO:0015820 leucine transport
Biological Process GO:0050900 leukocyte migration
Biological Process GO:1903801 L-leucine import across plasma membrane
Biological Process GO:0055065 metal ion homeostasis
Biological Process GO:0015804 neutral amino acid transport
Biological Process GO:0035524 proline transmembrane transport
Biological Process GO:0009636 response to toxic substance
Biological Process GO:0070327 thyroid hormone transport
Biological Process GO:0150104 transport across blood-brain barrier
Biological Process GO:0015827 tryptophan transport
Biological Process GO:0015829 valine transport
molecular function GO:0015171 amino acid transmembrane transporter activity
molecular function GO:0015187 glycine transmembrane transporter activity
molecular function GO:0015180 L-alanine transmembrane transporter activity
molecular function GO:0015179 L-amino acid transmembrane transporter activity
molecular function GO:0015190 L-leucine transmembrane transporter activity
molecular function GO:0015175 neutral amino acid transmembrane transporter activity
molecular function GO:0015101 organic cation transmembrane transporter activity
molecular function GO:0042605 peptide antigen binding
molecular function GO:0015349 thyroid hormone transmembrane transporter activity
molecular function GO:0019534 toxin transmembrane transporter activity
cellular component GO:0016324 apical plasma membrane
cellular component GO:0009925 basal plasma membrane
cellular component GO:0016323 basolateral plasma membrane
cellular component GO:0005737 cytoplasm
cellular component GO:0005887 integral component of plasma membrane
cellular component GO:0031528 microvillus membrane
cellular component GO:0005886 plasma membrane
Reactome
Pathway Id Pathway Name
R-HSA-109582 Hemostasis
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-210991 Basigin interactions
R-HSA-352230 Amino acid transport across the plasma membrane
R-HSA-382551 Transport of small molecules
R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides
R-HSA-425407 SLC-mediated transmembrane transport
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0014175 BXGD000904 Endometriosis Female Urogenital Diseases and Pregnancy Complications
C0018776 BXGD001216 Hearing Loss, Central Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018780 BXGD001218 Hearing Loss, High-Frequency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0018784 BXGD001220 Sensorineural Hearing Loss (disorder) Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C0023267 BXGD001626 Fibroid Tumor Neoplasms
C0027051 BXGD001963 Myocardial Infarction Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C0042133 BXGD002960 Uterine Fibroids Neoplasms
C0235974 BXGD004796 Pancreatic carcinoma Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0268647 BXGD006024 Lysinuric Protein Intolerance Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0346647 BXGD007832 Malignant neoplasm of pancreas Digestive System Diseases; Neoplasms; Endocrine System Diseases
C0349588 BXGD007933 Short stature
C0427460 BXGD008616 Red cell distribution width determination
C1304746 BXGD012343 RDW - Red blood cell distribution width result
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C3811653 BXGD019662 Experimental Organism Basal Cell Carcinoma Neoplasms
C4721806 BXGD023772 Carcinoma, Basal Cell Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000279 L-Alanine 89.09
BXGC0003214 L-(-)-Phenylalanine 165.19
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein