Showing entry for Ras-related protein Rab-21


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021753
Protein NameRas-related protein Rab-21
Uniport IdQ9UL25
GeneRAB21
Gene Id23011
DomainRas
Pfam PF00071  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0008089 anterograde axonal transport
Biological Process GO:0006886 intracellular protein transport
Biological Process GO:0050775 positive regulation of dendrite morphogenesis
Biological Process GO:2000643 positive regulation of early endosome to late endosome transport
Biological Process GO:0048260 positive regulation of receptor-mediated endocytosis
Biological Process GO:0032482 Rab protein signal transduction
Biological Process GO:0030516 regulation of axon extension
Biological Process GO:0017157 regulation of exocytosis
molecular function GO:0019003 GDP binding
molecular function GO:0003924 GTPase activity
molecular function GO:0005525 GTP binding
cellular component GO:1904115 axon cytoplasm
cellular component GO:0032154 cleavage furrow
cellular component GO:0098559 cytoplasmic side of early endosome membrane
cellular component GO:0009898 cytoplasmic side of plasma membrane
cellular component GO:0030659 cytoplasmic vesicle membrane
cellular component GO:0005829 cytosol
cellular component GO:0005769 early endosome
cellular component GO:0031901 early endosome membrane
cellular component GO:0012505 endomembrane system
cellular component GO:0005789 endoplasmic reticulum membrane
cellular component GO:0005768 endosome
cellular component GO:0070062 extracellular exosome
cellular component GO:0005925 focal adhesion
cellular component GO:0032580 Golgi cisterna membrane
cellular component GO:0045202 synapse
cellular component GO:0005802 trans-Golgi network
cellular component GO:0012506 vesicle membrane
Reactome
Pathway Id Pathway Name
R-HSA-199991 Membrane Trafficking
R-HSA-392499 Metabolism of proteins
R-HSA-5653656 Vesicle-mediated transport
R-HSA-597592 Post-translational protein modification
R-HSA-8873719 RAB geranylgeranylation
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-9007101 Rab regulation of trafficking
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001339 BXGD000041 Acute pancreatitis Digestive System Diseases
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002726 BXGD000125 Amyloidosis Nutritional and Metabolic Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0017638 BXGD001132 Glioma Neoplasms
C0021704 BXGD001510 Intelligence Behavior and Behavior Mechanisms
C0023508 BXGD001675 White Blood Cell Count procedure
C0028754 BXGD002082 Obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C0202117 BXGD004074 Low density lipoprotein cholesterol measurement
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C1305855 BXGD012348 Body mass index
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein