adisease

Showing entry for Amyloidosis

General Disease Information
BXGD Id	BXGD000125
Disease Name	Amyloidosis
Disease CUI Id	C0002726
MeSH Codes	C18
Disease Class Name	Nutritional and Metabolic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001939
Human Phenotype Ontology Term	Abnormality of metabolism/homeostasis
Disease Ontology Id	DOID:0014667
Disease Ontology Class Name	disease of metabolism
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
F7VJQ1	BXGT003310	Alternative prion protein	5621	reviewed
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00418	BXGT003918	Eukaryotic elongation factor 2 kinase	29904	reviewed	Kinase
O00429	BXGT003919	Dynamin-1-like protein	10059	reviewed	Enzyme modulator
O00767	BXGT003949	Acyl-CoA desaturase	6319	reviewed
O14672	BXGT004081	Disintegrin and metalloproteinase domain-containing protein 10	102	reviewed
O14727	BXGT004084	Apoptotic protease-activating factor 1	317	reviewed
O14744	BXGT004089	Protein arginine N-methyltransferase 5	10419	reviewed	Epigenetic regulator
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	4864	reviewed	Transporter
O15169	BXGT004134	Axin-1	8312	reviewed
O15379	BXGT004159	Histone deacetylase 3	8841	reviewed	Epigenetic regulator
O15553	BXGT004181	Pyrin	4210	reviewed
O43464	BXGT004595	Serine protease HTRA2, mitochondrial	27429	reviewed
O43521	BXGT004598	Bcl-2-like protein 11	10018	reviewed
O43612	BXGT004605	Orexin	3060	reviewed
O43914	BXGT004635	TYRO protein tyrosine kinase-binding protein	7305	reviewed
O60259	BXGT004863	Kallikrein-8	11202	reviewed	Enzyme
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O75385	BXGT005121	Serine/threonine-protein kinase ULK1	8408	reviewed	Kinase
O75923	BXGT005166	Dysferlin	8291	reviewed	Transporter
O76074	BXGT005174	cGMP-specific 3',5'-cyclic phosphodiesterase	8654	reviewed
O76096	BXGT005178	Cystatin-F	8530	reviewed
O94760	BXGT005328	N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	23576	reviewed	Enzyme
O94811	BXGT005336	Tubulin polymerization-promoting protein	11076	reviewed	Cellular structure
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
O95255	BXGT005363	Multidrug resistance-associated protein 6	368	reviewed	Transporter
O95477	BXGT005383	Phospholipid-transporting ATPase ABCA1	19	reviewed	Transporter
P00441	BXGT005540	Superoxide dismutase [Cu-Zn]	6647	reviewed	Enzyme
P00742	BXGT005636	Coagulation factor X	2159	reviewed	Enzyme
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01008	BXGT005713	Antithrombin-III	462	reviewed	Enzyme modulator
P01011	BXGT005715	Alpha-1-antichymotrypsin	12	reviewed	Enzyme modulator
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01023	BXGT005718	Alpha-2-macroglobulin	2	reviewed	Enzyme modulator
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01042	BXGT005722	Kininogen-1	3827	reviewed	Enzyme modulator
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P01130	BXGT005735	Low-density lipoprotein receptor	3949	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01138	BXGT005738	Beta-nerve growth factor	4803	reviewed	Signaling
P01275	BXGT005747	Glucagon	2641	reviewed
P01303	BXGT005748	Pro-neuropeptide Y	4852	reviewed	Signaling
P01308	BXGT005749	Insulin	3630	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02649	BXGT005909	Apolipoprotein E	348	reviewed
P02652	BXGT005910	Apolipoprotein A-II	336	reviewed	Transporter
P02655	BXGT005912	Apolipoprotein C-II	344	reviewed
P02656	BXGT005913	Apolipoprotein C-III	345	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02743	BXGT005937	Serum amyloid P-component	325	reviewed
P02746	BXGT005938	Complement C1q subcomponent subunit B	713	reviewed
P02747	BXGT005939	Complement C1q subcomponent subunit C	714	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P02753	BXGT005945	Retinol-binding protein 4	5950	reviewed	Transporter
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04003	BXGT006124	C4b-binding protein alpha chain	722	reviewed
P04004	BXGT006125	Vitronectin	7448	reviewed
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04156	BXGT006156	Major prion protein	5621	reviewed
P04179	BXGT006163	Superoxide dismutase [Mn], mitochondrial	6648	reviewed	Enzyme
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04279	BXGT006183	Semenogelin-1	6406	reviewed
P04406	BXGT006207	Glyceraldehyde-3-phosphate dehydrogenase	2597	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05067	BXGT006306	Amyloid-beta precursor protein	351	reviewed	Enzyme modulator
P05089	BXGT006310	Arginase-1	383	reviewed	Enzyme
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06213	BXGT006425	Insulin receptor	3643	reviewed	Kinase
P06241	BXGT006429	Tyrosine-protein kinase Fyn	2534	reviewed	Kinase
P06276	BXGT006430	Cholinesterase	590	reviewed
P06396	BXGT006435	Gelsolin	2934	reviewed	Cellular structure
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06703	BXGT006477	Protein S100-A6	6277	reviewed	Calcium-binding protein
P06727	BXGT006485	Apolipoprotein A-IV	337	reviewed
P06746	BXGT006496	DNA polymerase beta	5423	reviewed	Enzyme
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07203	BXGT006566	Glutathione peroxidase 1	2876	reviewed	Enzyme
P07339	BXGT006604	Cathepsin D	1509	reviewed	Enzyme
P07741	BXGT006666	Adenine phosphoribosyltransferase	353	reviewed
P07858	BXGT006689	Cathepsin B	1508	reviewed	Enzyme
P07900	BXGT006696	Heat shock protein HSP 90-alpha	3320	reviewed	Chaperone
P07949	BXGT006703	Proto-oncogene tyrosine-protein kinase receptor Ret	5979	reviewed	Kinase
P08174	BXGT006739	Complement decay-accelerating factor	1604	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08397	BXGT006768	Porphobilinogen deaminase	3145	reviewed	Enzyme
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08575	BXGT006793	Receptor-type tyrosine-protein phosphatase C	5788	reviewed	Enzyme
P08758	BXGT006821	Annexin A5	308	reviewed
P08842	BXGT006830	Steryl-sulfatase	412	reviewed	Enzyme
P08922	BXGT006843	Proto-oncogene tyrosine-protein kinase ROS	6098	reviewed	Kinase
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P09874	BXGT006934	Poly [ADP-ribose] polymerase 1	142	reviewed
P09884	BXGT006937	DNA polymerase alpha catalytic subunit	5422	reviewed
P09917	BXGT006941	Arachidonate 5-lipoxygenase	240	reviewed	Enzyme
P09936	BXGT006943	Ubiquitin carboxyl-terminal hydrolase isozyme L1	7345	reviewed	Enzyme
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P10636	BXGT007596	Microtubule-associated protein tau	4137	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P10826	BXGT007622	Retinoic acid receptor beta	5915	reviewed	Nuclear receptor
P10909	BXGT007630	Clusterin	1191	reviewed
P10997	BXGT007643	Islet amyloid polypeptide	3375	reviewed	Signaling
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P11274	BXGT007681	Breakpoint cluster region protein	613	reviewed	Enzyme modulator
P11413	BXGT007701	Glucose-6-phosphate 1-dehydrogenase	2539	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14735	BXGT008042	Insulin-degrading enzyme	3416	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15289	BXGT008102	Arylsulfatase A	410	reviewed	Enzyme
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16050	BXGT008184	Arachidonate 15-lipoxygenase	246	reviewed	Enzyme
P16435	BXGT008226	NADPH--cytochrome P450 reductase	5447	reviewed
P16671	BXGT008255	Platelet glycoprotein 4	948	reviewed	Receptor
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P17516	BXGT008313	Aldo-keto reductase family 1 member C4	1109	reviewed	Enzyme
P17643	BXGT008323	5,6-dihydroxyindole-2-carboxylic acid oxidase	7306	reviewed	Enzyme
P17735	BXGT008335	Tyrosine aminotransferase	6898	reviewed
P17861	BXGT008348	X-box-binding protein 1	7494	reviewed
P18054	BXGT008370	Arachidonate 12-lipoxygenase, 12S-type	239	reviewed	Enzyme
P18146	BXGT008384	Early growth response protein 1	1958	reviewed	Nucleic acid binding
P18827	BXGT008427	Syndecan-1	6382	reviewed	Extracellular structure
P18848	BXGT008432	Cyclic AMP-dependent transcription factor ATF-4	468	reviewed
P18850	BXGT008433	Cyclic AMP-dependent transcription factor ATF-6 alpha	22926	reviewed
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19793	BXGT008515	Retinoic acid receptor RXR-alpha	6256	reviewed	Nuclear receptor
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20132	BXGT008546	L-serine dehydratase/L-threonine deaminase	10993	reviewed	Enzyme
P20309	BXGT008562	Muscarinic acetylcholine receptor M3	1131	reviewed	G-protein coupled receptor
P20472	BXGT008578	Parvalbumin alpha	5816	reviewed	Calcium-binding protein
P20851	BXGT008609	C4b-binding protein beta chain	725	reviewed
P21397	BXGT008644	Amine oxidase [flavin-containing] A	4128	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21709	BXGT008685	Ephrin type-A receptor 1	2041	reviewed	Kinase
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P22303	BXGT008751	Acetylcholinesterase	43	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P24752	BXGT008993	Acetyl-CoA acetyltransferase, mitochondrial	38	reviewed	Enzyme
P25025	BXGT009006	C-X-C chemokine receptor type 2	3579	reviewed	G-protein coupled receptor
P25713	BXGT009062	Metallothionein-3	4504	reviewed
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	3356	reviewed	G-protein coupled receptor
P28329	BXGT009251	Choline O-acetyltransferase	1103	reviewed	Enzyme
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29320	BXGT009332	Ephrin type-A receptor 3	2042	reviewed	Kinase
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P30405	BXGT009423	Peptidyl-prolyl cis-trans isomerase F, mitochondrial	10105	reviewed
P30536	BXGT009435	Translocator protein	706	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P31749	BXGT009574	RAC-alpha serine/threonine-protein kinase	207	reviewed	Kinase
P31948	BXGT009590	Stress-induced-phosphoprotein 1	10963	reviewed
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P33527	BXGT009728	Multidrug resistance-associated protein 1	4363	reviewed	Transporter
P34059	BXGT009749	N-acetylgalactosamine-6-sulfatase	2588	reviewed	Enzyme
P34932	BXGT009772	Heat shock 70 kDa protein 4	3308	reviewed
P34972	BXGT009779	Cannabinoid receptor 2	1269	reviewed	G-protein coupled receptor
P34998	BXGT009781	Corticotropin-releasing factor receptor 1	1394	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P35613	BXGT009856	Basigin	682	reviewed
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P36544	BXGT009926	Neuronal acetylcholine receptor subunit alpha-7	89832	reviewed
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P37173	BXGT009970	TGF-beta receptor type-2	7048	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40967	BXGT010212	Melanocyte protein PMEL	6490	reviewed	Signaling
P41180	BXGT010230	Extracellular calcium-sensing receptor	846	reviewed	G-protein coupled receptor
P41231	BXGT010240	P2Y purinoceptor 2	5029	reviewed	G-protein coupled receptor
P41594	BXGT010266	Metabotropic glutamate receptor 5	2915	reviewed	G-protein coupled receptor
P42261	BXGT010293	Glutamate receptor 1	2890	reviewed	Ion channel
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42345	BXGT010304	Serine/threonine-protein kinase mTOR	2475	reviewed	Kinase
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P42858	BXGT010341	Huntingtin	3064	reviewed
P43003	BXGT010347	Excitatory amino acid transporter 1	6507	reviewed	Transporter
P43681	BXGT010407	Neuronal acetylcholine receptor subunit alpha-4	1137	reviewed	Ion channel
P45983	BXGT010494	Mitogen-activated protein kinase 8	5599	reviewed	Kinase
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46939	BXGT010555	Utrophin	7402	reviewed
P47712	BXGT010577	Cytosolic phospholipase A2	5321	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P49281	BXGT010689	Natural resistance-associated macrophage protein 2	4891	reviewed	Transporter
P49768	BXGT010740	Presenilin-1	5663	reviewed	Enzyme
P49810	BXGT010747	Presenilin-2	5664	reviewed	Enzyme
P49840	BXGT010749	Glycogen synthase kinase-3 alpha	2931	reviewed	Kinase
P49841	BXGT010750	Glycogen synthase kinase-3 beta	2932	reviewed	Kinase
P49917	BXGT010765	DNA ligase 4	3981	reviewed
P50453	BXGT010799	Serpin B9	5272	reviewed	Enzyme modulator
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51693	BXGT010886	Amyloid-like protein 1	333	reviewed	Enzyme modulator
P51790	BXGT010890	H(+)/Cl(-) exchange transporter 3	1182	reviewed	Ion channel
P52564	BXGT010932	Dual specificity mitogen-activated protein kinase kinase 6	5608	reviewed	Kinase
P53350	BXGT010984	Serine/threonine-protein kinase PLK1	5347	reviewed	Kinase
P53667	BXGT011008	LIM domain kinase 1	3984	reviewed	Kinase
P53778	BXGT011013	Mitogen-activated protein kinase 12	6300	reviewed	Kinase
P54802	BXGT011081	Alpha-N-acetylglucosaminidase	4669	reviewed
P55040	BXGT011099	GTP-binding protein GEM	2669	reviewed
P55055	BXGT011101	Oxysterols receptor LXR-beta	7376	reviewed	Nuclear receptor
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P55899	BXGT011131	IgG receptor FcRn large subunit p51	2217	reviewed
P56817	BXGT011200	Beta-secretase 1	23621	reviewed	Enzyme
P56945	BXGT011206	Breast cancer anti-estrogen resistance protein 1	9564	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P61626	BXGT011382	Lysozyme C	4069	reviewed
P61769	BXGT011383	Beta-2-microglobulin	567	reviewed	Immune response
P62491	BXGT011430	Ras-related protein Rab-11A	8766	reviewed
P63098	BXGT011497	Calcineurin subunit B type 1	5534	reviewed
P78352	BXGT011836	Disks large homolog 4	1742	reviewed	Receptor
P80188	BXGT011882	Neutrophil gelatinase-associated lipocalin	3934	reviewed	Enzyme
P98160	BXGT012228	Basement membrane-specific heparan sulfate proteoglycan core protein	3339	reviewed	Enzyme modulator
Q00535	BXGT012534	Cyclin-dependent-like kinase 5	1020	reviewed	Kinase
Q00613	BXGT012540	Heat shock factor protein 1	3297	reviewed	Transcription factor
Q01094	BXGT012568	Transcription factor E2F1	1869	reviewed	Nucleic acid binding
Q01453	BXGT012588	Peripheral myelin protein 22	5376	reviewed	Cellular structure
Q01959	BXGT012624	Sodium-dependent dopamine transporter	6531	reviewed	Transporter
Q02363	BXGT012650	DNA-binding protein inhibitor ID-2	3398	reviewed	Transcription factor
Q02750	BXGT012662	Dual specificity mitogen-activated protein kinase kinase 1	5604	reviewed	Kinase
Q03181	BXGT012701	Peroxisome proliferator-activated receptor delta	5467	reviewed	Nuclear receptor
Q05193	BXGT012810	Dynamin-1	1759	reviewed	Enzyme modulator
Q05586	BXGT012826	Glutamate receptor ionotropic, NMDA 1	2902	reviewed	Ion channel
Q06418	BXGT012875	Tyrosine-protein kinase receptor TYRO3	7301	reviewed	Kinase
Q06481	BXGT012878	Amyloid-like protein 2	334	reviewed	Enzyme modulator
Q07021	BXGT012915	Complement component 1 Q subcomponent-binding protein, mitochondrial	708	reviewed
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q07954	BXGT012950	Prolow-density lipoprotein receptor-related protein 1	4035	reviewed
Q08345	BXGT012982	Epithelial discoidin domain-containing receptor 1	780	reviewed	Kinase
Q12778	BXGT013263	Forkhead box protein O1	2308	reviewed
Q12882	BXGT013276	Dihydropyrimidine dehydrogenase [NADP(+)]	1806	reviewed	Enzyme
Q13093	BXGT013310	Platelet-activating factor acetylhydrolase	7941	reviewed	Enzyme
Q13133	BXGT013315	Oxysterols receptor LXR-alpha	10062	reviewed	Nuclear receptor
Q13137	BXGT013316	Calcium-binding and coiled-coil domain-containing protein 2	10241	reviewed
Q13148	BXGT013318	TAR DNA-binding protein 43	23435	reviewed
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13224	BXGT013328	Glutamate receptor ionotropic, NMDA 2B	2904	reviewed	Ion channel
Q13231	BXGT013329	Chitotriosidase-1	1118	reviewed
Q13285	BXGT013335	Steroidogenic factor 1	2516	reviewed	Nuclear receptor
Q13489	BXGT013364	Baculoviral IAP repeat-containing protein 3	330	reviewed	Enzyme modulator
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q13526	BXGT013369	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	5300	reviewed
Q13546	BXGT013372	Receptor-interacting serine/threonine-protein kinase 1	8737	reviewed	Kinase
Q13555	BXGT013375	Calcium/calmodulin-dependent protein kinase type II subunit gamma	818	reviewed	Kinase
Q13627	BXGT013385	Dual specificity tyrosine-phosphorylation-regulated kinase 1A	1859	reviewed	Kinase
Q13936	BXGT013404	Voltage-dependent L-type calcium channel subunit alpha-1C	775	reviewed	Ion channel
Q14114	BXGT013441	Low-density lipoprotein receptor-related protein 8	7804	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14145	BXGT013448	Kelch-like ECH-associated protein 1	9817	reviewed
Q14393	BXGT013466	Growth arrest-specific protein 6	2621	reviewed	Extracellular structure
Q14416	BXGT013468	Metabotropic glutamate receptor 2	2912	reviewed	G-protein coupled receptor
Q14457	BXGT013472	Beclin-1	8678	reviewed	Enzyme modulator
Q14624	BXGT013491	Inter-alpha-trypsin inhibitor heavy chain H4	3700	reviewed	Enzyme modulator
Q14832	BXGT013507	Metabotropic glutamate receptor 3	2913	reviewed	G-protein coupled receptor
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15257	BXGT013554	Serine/threonine-protein phosphatase 2A activator	5524	reviewed	Enzyme modulator
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q15831	BXGT013604	Serine/threonine-protein kinase STK11	6794	reviewed	Kinase
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16555	BXGT013638	Dihydropyrimidinase-related protein 2	1808	reviewed	Enzyme
Q16566	BXGT013639	Calcium/calmodulin-dependent protein kinase type IV	814	reviewed	Kinase
Q16568	BXGT013640	Cocaine- and amphetamine-regulated transcript protein	9607	reviewed
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q16698	BXGT013659	2,4-dienoyl-CoA reductase, mitochondrial	1666	reviewed	Enzyme
Q16769	BXGT013665	Glutaminyl-peptide cyclotransferase	25797	reviewed	Enzyme
Q16828	BXGT013676	Dual specificity protein phosphatase 6	1848	reviewed
Q30201	BXGT014297	Hereditary hemochromatosis protein	3077	reviewed
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q6GTX8	BXGT016315	Leukocyte-associated immunoglobulin-like receptor 1	3903	reviewed	Receptor
Q8IWS0	BXGT018356	PHD finger protein 6	84295	reviewed	Nucleic acid binding
Q8N5H7	BXGT018518	SH2 domain-containing protein 3C	10044	reviewed
Q8NBP7	BXGT018541	Proprotein convertase subtilisin/kexin type 9	255738	reviewed	Enzyme
Q8WUM4	BXGT018994	Programmed cell death 6-interacting protein	10015	reviewed	Receptor
Q92542	BXGT019354	Nicastrin	23385	reviewed
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92993	BXGT019403	Histone acetyltransferase KAT5	10524	reviewed
Q96AC1	BXGT019617	Fermitin family homolog 2	10979	reviewed
Q96BI3	BXGT019623	Gamma-secretase subunit APH-1A	51107	reviewed	Enzyme modulator
Q96EB6	BXGT019646	NAD-dependent protein deacetylase sirtuin-1	23411	reviewed	Epigenetic regulator
Q96IY4	BXGT019678	Carboxypeptidase B2	1361	reviewed	Enzyme
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96QV1	BXGT019722	Hedgehog-interacting protein	64399	reviewed
Q99523	BXGT019929	Sortilin	6272	reviewed	Transporter
Q99572	BXGT019935	P2X purinoceptor 7	5027	reviewed	Ion channel
Q99683	BXGT019947	Mitogen-activated protein kinase kinase kinase 5	4217	reviewed	Kinase
Q99784	BXGT019961	Noelin	10439	reviewed	Cellular structure
Q99828	BXGT019967	Calcium and integrin-binding protein 1	10519	reviewed
Q99962	BXGT019978	Endophilin-A1	6456	reviewed
Q99972	BXGT019979	Myocilin	4653	reviewed	Cellular structure
Q9BXM7	BXGT020172	Serine/threonine-protein kinase PINK1, mitochondrial	65018	reviewed	Kinase
Q9C000	BXGT020206	NACHT, LRR and PYD domains-containing protein 1	22861	reviewed
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H816	BXGT020494	5' exonuclease Apollo	64858	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9NP58	BXGT021143	ATP-binding cassette sub-family B member 6, mitochondrial	10058	reviewed	Transporter
Q9NP99	BXGT021148	Triggering receptor expressed on myeloid cells 1	54210	reviewed
Q9NPG2	BXGT021155	Neuroglobin	58157	reviewed	Transporter
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NRF2	BXGT021185	SH2B adapter protein 1	25970	reviewed
Q9NTG7	BXGT021211	NAD-dependent protein deacetylase sirtuin-3, mitochondrial	23410	reviewed	Epigenetic regulator
Q9NYB9	BXGT021256	Abl interactor 2	10152	reviewed	Enzyme modulator
Q9P2R7	BXGT021304	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	8803	reviewed	Enzyme
Q9UIK4	BXGT021720	Death-associated protein kinase 2	23604	reviewed	Kinase
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9UKV0	BXGT021750	Histone deacetylase 9	9734	reviewed	Epigenetic regulator
Q9UL25	BXGT021753	Ras-related protein Rab-21	23011	reviewed
Q9UQL6	BXGT021813	Histone deacetylase 5	10014	reviewed	Epigenetic regulator
Q9Y572	BXGT022289	Receptor-interacting serine/threonine-protein kinase 3	11035	reviewed	Kinase
Q9Y5Z0	BXGT022310	Beta-secretase 2	25825	reviewed	Enzyme
Q9Y6A2	BXGT022324	Cholesterol 24-hydroxylase	10858	reviewed	Enzyme
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
Q92911	BXGT022650	Sodium/iodide cotransporter	6528	reviewed	Transporter
P00738	BXGT022874	Haptoglobin	3240	reviewed	Enzyme
Q9UK05	BXGT023094	Growth/differentiation factor 2	2658	reviewed	Signaling
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q9GZQ8	BXGT023414	Microtubule-associated proteins 1A/1B light chain 3B	81631	reviewed	Cellular structure
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme
P20138	BXGT023857	Myeloid cell surface antigen CD33	945	reviewed	Receptor
Q96QC4	BXGT023878	MHC class I polypeptide-related sequence A	100507436	unreviewed
Q96A54	BXGT024681	Adiponectin receptor protein 1	51094	reviewed	Receptor
O43583	BXGT024866	Density-regulated protein	8562	reviewed	Enzyme
P38646	BXGT024954	Stress-70 protein, mitochondrial	3313	reviewed
P19474	BXGT025520	E3 ubiquitin-protein ligase TRIM21	6737	reviewed
Q15818	BXGT026007	Neuronal pentraxin-1	4884	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}