Showing entry for Protein-arginine deiminase type-3


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT021768
Protein NameProtein-arginine deiminase type-3
Uniport IdQ9ULW8
GenePADI3
Gene Id51702
DomainPAD; PAD_M; PAD_N
Pfam PF03068   PF08527   PF08526  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006325 chromatin organization
Biological Process GO:0036414 histone citrullination
Biological Process GO:0018101 protein citrullination
molecular function GO:0005509 calcium ion binding
molecular function GO:0042802 identical protein binding
molecular function GO:0004668 protein-arginine deiminase activity
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0005634 nucleus
Reactome
Pathway Id Pathway Name
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002171 BXGD000106 Alopecia Areata Skin and Connective Tissue Diseases
C0003873 BXGD000236 Rheumatoid Arthritis Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0016529 BXGD001068 Forced expiratory volume function
C0018498 BXGD001195 Hair Color
C0024115 BXGD001732 Lung diseases Respiratory Tract Diseases
C0035227 BXGD002514 Respiratory Function Tests
C0206062 BXGD004148 Lung Diseases, Interstitial Respiratory Tract Diseases
C0239804 BXGD004995 White hair
C0277959 BXGD006487 Coarse hair
C0277960 BXGD006488 Dry hair
C0343073 BXGD007597 Wooly hair Skin and Connective Tissue Diseases
C0432347 BXGD008779 Uncombable hair syndrome Skin and Connective Tissue Diseases
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C1274708 BXGD012041 Central centrifugal cicatricial alopecia
C1860607 BXGD015990 Uncombable hair
C1860608 BXGD015991 Pili canaliculi
C4025700 BXGD021740 Trichodysplasia
C4551573 BXGD023360 UNCOMBABLE HAIR SYNDROME 1 Skin and Connective Tissue Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0003852 Nigrin B 506.47
BXGC0014919 Citrulline 175.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein