Showing entry for Lung Diseases, Interstitial


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004148
Disease NameLung Diseases, Interstitial
Disease CUI IdC0206062
MeSH Codes C08  
Disease Class NameRespiratory Tract Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0002086  
Human Phenotype Ontology TermAbnormality of the respiratory system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O14618 BXGT004076 Copper chaperone for superoxide dismutase 9973 reviewed Enzyme
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O43612 BXGT004605 Orexin 3060 reviewed
O43776 BXGT004624 Asparagine--tRNA ligase, cytoplasmic 4677 reviewed Enzyme
O60486 BXGT004877 Plexin-C1 10154 reviewed
O60760 BXGT004899 Hematopoietic prostaglandin D synthase 27306 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O75636 BXGT005141 Ficolin-3 8547 reviewed Signaling
O76054 BXGT005172 SEC14-like protein 2 23541 reviewed
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
P00439 BXGT005539 Phenylalanine-4-hydroxylase 5053 reviewed
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02533 BXGT005887 Keratin, type I cytoskeletal 14 3861 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04004 BXGT006125 Vitronectin 7448 reviewed
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04155 BXGT006155 Trefoil factor 1 7031 reviewed Signaling
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06734 BXGT006491 Low affinity immunoglobulin epsilon Fc receptor 2208 reviewed Receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C 5788 reviewed Enzyme
P08697 BXGT006815 Alpha-2-antiplasmin 5345 reviewed Enzyme modulator
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09237 BXGT006874 Matrilysin 4316 reviewed Enzyme
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10147 BXGT007543 C-C motif chemokine 3 6348 reviewed Signaling
P10323 BXGT007557 Acrosin 49 reviewed Enzyme
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10636 BXGT007596 Microtubule-associated protein tau 4137 reviewed
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13501 BXGT007917 C-C motif chemokine 5 6352 reviewed Signaling
P14207 BXGT007993 Folate receptor beta 2350 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15311 BXGT008106 Ezrin 7430 reviewed Cellular structure
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15924 BXGT008171 Desmoplakin 1832 reviewed Cellular structure
P15941 BXGT008176 Mucin-1 4582 reviewed
P17405 BXGT008304 Sphingomyelin phosphodiesterase 6609 reviewed Enzyme
P18847 BXGT008431 Cyclic AMP-dependent transcription factor ATF-3 467 reviewed Transcription factor
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P20273 BXGT008557 B-cell receptor CD22 933 reviewed
P20292 BXGT008561 Arachidonate 5-lipoxygenase-activating protein 241 reviewed Enzyme
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20936 BXGT008619 Ras GTPase-activating protein 1 5921 reviewed Enzyme modulator
P21333 BXGT008638 Filamin-A 2316 reviewed
P22897 BXGT008816 Macrophage mannose receptor 1 4360 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24158 BXGT008951 Myeloblastin 5657 reviewed Enzyme
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P29400 BXGT009343 Collagen alpha-5(IV) chain 1287 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30874 BXGT009475 Somatostatin receptor type 2 6752 reviewed G-protein coupled receptor
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35475 BXGT009837 Alpha-L-iduronidase 3425 reviewed Enzyme
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P35754 BXGT009863 Glutaredoxin-1 2745 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36551 BXGT009927 Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial 1371 reviewed Enzyme
P36897 BXGT009941 TGF-beta receptor type-1 7046 reviewed Kinase
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P46937 BXGT010554 Transcriptional coactivator YAP1 10413 reviewed Enzyme modulator
P49721 BXGT010730 Proteasome subunit beta type-2 5690 reviewed
P51451 BXGT010848 Tyrosine-protein kinase Blk 640 reviewed Kinase
P51677 BXGT010876 C-C chemokine receptor type 3 1232 reviewed G-protein coupled receptor
P55087 BXGT011105 Aquaporin-4 361 reviewed Ion channel
P55774 BXGT011124 C-C motif chemokine 18 6362 reviewed Signaling
P56192 BXGT011149 Methionine--tRNA ligase, cytoplasmic 4141 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
P61626 BXGT011382 Lysozyme C 4069 reviewed
P78536 BXGT011847 Disintegrin and metalloproteinase domain-containing protein 17 6868 reviewed
P98160 BXGT012228 Basement membrane-specific heparan sulfate proteoglycan core protein 3339 reviewed Enzyme modulator
P99999 BXGT012235 Cytochrome c 54205 reviewed
Q13231 BXGT013329 Chitotriosidase-1 1118 reviewed
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q13887 BXGT013401 Krueppel-like factor 5 688 reviewed Nucleic acid binding
Q14108 BXGT013440 Lysosome membrane protein 2 950 reviewed Receptor
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14149 BXGT013449 MORC family CW-type zinc finger protein 3 23515 reviewed
Q14232 BXGT013457 Translation initiation factor eIF-2B subunit alpha 1967 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q15485 BXGT013574 Ficolin-2 2220 reviewed Signaling
Q30154 BXGT014296 HLA class II histocompatibility antigen, DR beta 5 chain 3127 reviewed Immune response
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q6ZMJ4 BXGT016628 Interleukin-34 146433 reviewed
Q7Z3B3 BXGT017249 KAT8 regulatory NSL complex subunit 1 284058 reviewed
Q86WV6 BXGT017626 Stimulator of interferon genes protein 340061 reviewed
Q8WWY3 BXGT019006 U4/U6 small nuclear ribonucleoprotein Prp31 26121 reviewed Nucleic acid binding
Q92769 BXGT019370 Histone deacetylase 2 3066 reviewed Epigenetic regulator
Q96F46 BXGT019656 Interleukin-17 receptor A 23765 reviewed
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q99581 BXGT019937 Protein FEV 54738 reviewed Transcription factor
Q9BXM7 BXGT020172 Serine/threonine-protein kinase PINK1, mitochondrial 65018 reviewed Kinase
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NRR6 BXGT021193 Phosphatidylinositol polyphosphate 5-phosphatase type IV 56623 reviewed
Q9NSD9 BXGT021206 Phenylalanine--tRNA ligase beta subunit 10056 reviewed Enzyme
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9ULW8 BXGT021768 Protein-arginine deiminase type-3 51702 reviewed
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9UPN9 BXGT021799 E3 ubiquitin-protein ligase TRIM33 51592 reviewed
Q9Y275 BXGT022223 Tumor necrosis factor ligand superfamily member 13B 10673 reviewed
Q9Y2J8 BXGT022237 Protein-arginine deiminase type-2 11240 reviewed
Q9Y4K0 BXGT022280 Lysyl oxidase homolog 2 4017 reviewed
Q96C86 BXGT022803 m7GpppX diphosphatase 28960 reviewed Enzyme
P15509 BXGT022826 Granulocyte-macrophage colony-stimulating factor receptor subunit alpha 1438 reviewed Signaling
Q01543 BXGT023137 Friend leukemia integration 1 transcription factor 2313 reviewed Transcription factor
P31994 BXGT023298 Low affinity immunoglobulin gamma Fc region receptor II-b 2213 reviewed Cell adhesion
Q9GZQ8 BXGT023414 Microtubule-associated proteins 1A/1B light chain 3B 81631 reviewed Cellular structure
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
Q8IYW5 BXGT023493 E3 ubiquitin-protein ligase RNF168 165918 reviewed
P56703 BXGT023722 Proto-oncogene Wnt-3 7473 reviewed Signaling
P53621 BXGT025196 Coatomer subunit alpha 1314 reviewed Transporter
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
P11836 BXGT025994 B-lymphocyte antigen CD20 931 reviewed Receptor
P07320 BXGT026150 Gamma-crystallin D 1421 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease