adisease

Showing entry for Alopecia Areata

General Disease Information
BXGD Id	BXGD000106
Disease Name	Alopecia Areata
Disease CUI Id	C0002171
MeSH Codes	C17
Disease Class Name	Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0001574
Human Phenotype Ontology Term	Abnormality of the integument
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O75475	BXGT005130	PC4 and SFRS1-interacting protein	11168	reviewed	Signaling
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P01920	BXGT005817	HLA class II histocompatibility antigen, DQ beta 1 chain	3119	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07101	BXGT006547	Tyrosine 3-monooxygenase	7054	reviewed
P09455	BXGT006890	Retinol-binding protein 1	5947	reviewed
P0DMV8	BXGT007509	Heat shock 70 kDa protein 1A	3304	reviewed
P0DMV9	BXGT007510	Heat shock 70 kDa protein 1B	3304	reviewed
P10144	BXGT007541	Granzyme B	3002	reviewed	Enzyme
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14174	BXGT007991	Macrophage migration inhibitory factor	4282	reviewed
P16410	BXGT008224	Cytotoxic T-lymphocyte protein 4	1493	reviewed
P16442	BXGT008227	Histo-blood group ABO system transferase	28	reviewed	Enzyme
P19429	BXGT008479	Troponin I, cardiac muscle	7137	reviewed	Cellular structure
P20591	BXGT008586	Interferon-induced GTP-binding protein Mx1	4599	reviewed	Enzyme modulator
P20930	BXGT008616	Filaggrin	2312	reviewed	Cellular structure
P21860	BXGT008698	Receptor tyrosine-protein kinase erbB-3	2065	reviewed	Kinase
P23458	BXGT008868	Tyrosine-protein kinase JAK1	3716	reviewed	Kinase
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30044	BXGT009395	Peroxiredoxin-5, mitochondrial	25824	reviewed
P35610	BXGT009855	Sterol O-acyltransferase 1	6646	reviewed	Enzyme
P41229	BXGT010239	Lysine-specific demethylase 5C	8242	reviewed
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	6772	reviewed	Nucleic acid binding
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
Q01718	BXGT012609	Adrenocorticotropic hormone receptor	4158	reviewed	G-protein coupled receptor
Q03518	BXGT012723	Antigen peptide transporter 1	6890	reviewed	Transporter
Q08188	BXGT012965	Protein-glutamine gamma-glutamyltransferase E	7053	reviewed	Enzyme
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q5Y7D3	BXGT015912	HLA class II histocompatibility antigen DQ beta chain	3119	unreviewed
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q9BZM4	BXGT020200	UL16-binding protein 3	79465	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9NR96	BXGT021181	Toll-like receptor 9	54106	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9ULW8	BXGT021768	Protein-arginine deiminase type-3	51702	reviewed
Q9Y2R2	BXGT022243	Tyrosine-protein phosphatase non-receptor type 22	26191	reviewed
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
Q16552	BXGT023419	Interleukin-17A	3605	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}