Showing entry for RuvB-like 2


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT022208
Protein NameRuvB-like 2
Uniport IdQ9Y230
GeneRUVBL2
Gene Id10856
DomainTIP49; TIP49_C
Pfam PF06068   PF17856  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0000492 box C/D snoRNP assembly
Biological Process GO:0071392 cellular response to estradiol stimulus
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0006338 chromatin remodeling
Biological Process GO:0006310 DNA recombination
Biological Process GO:0006281 DNA repair
Biological Process GO:0071169 establishment of protein localization to chromatin
Biological Process GO:0016573 histone acetylation
Biological Process GO:0043968 histone H2A acetylation
Biological Process GO:0043967 histone H4 acetylation
Biological Process GO:0090090 negative regulation of canonical Wnt signaling pathway
Biological Process GO:0071899 negative regulation of estrogen receptor binding
Biological Process GO:0035066 positive regulation of histone acetylation
Biological Process GO:1904874 positive regulation of telomerase RNA localization to Cajal body
Biological Process GO:0045944 positive regulation of transcription by RNA polymerase II
Biological Process GO:0006457 protein folding
Biological Process GO:0040008 regulation of growth
Biological Process GO:0006357 regulation of transcription by RNA polymerase II
Biological Process GO:0071733 transcriptional activation by promoter-enhancer looping
molecular function GO:0043139 5'-3' DNA helicase activity
molecular function GO:0043531 ADP binding
molecular function GO:0051117 ATPase binding
molecular function GO:0005524 ATP binding
molecular function GO:0008013 beta-catenin binding
molecular function GO:0031490 chromatin DNA binding
molecular function GO:0003678 DNA helicase activity
molecular function GO:0042802 identical protein binding
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
molecular function GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding
molecular function GO:0017025 TBP-class protein binding
molecular function GO:0001094 TFIID-class transcription factor complex binding
molecular function GO:0003714 transcription corepressor activity
molecular function GO:0051082 unfolded protein binding
cellular component GO:0005813 centrosome
cellular component GO:0005737 cytoplasm
cellular component GO:0005829 cytosol
cellular component GO:0070062 extracellular exosome
cellular component GO:0031011 Ino80 complex
cellular component GO:0005622 intracellular
cellular component GO:0016020 membrane
cellular component GO:0071339 MLL1 complex
cellular component GO:0035267 NuA4 histone acetyltransferase complex
cellular component GO:0005719 nuclear euchromatin
cellular component GO:0016363 nuclear matrix
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0097255 R2TP complex
cellular component GO:1990904 ribonucleoprotein complex
cellular component GO:0000812 Swr1 complex
Reactome
Pathway Id Pathway Name
R-HSA-157579 Telomere Maintenance
R-HSA-1640170 Cell Cycle
R-HSA-171319 Telomere Extension By Telomerase
R-HSA-180786 Extension of Telomeres
R-HSA-3214847 HATs acetylate histones
R-HSA-3247509 Chromatin modifying enzymes
R-HSA-4839726 Chromatin organization
R-HSA-73886 Chromosome Maintenance
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007102 BXGD000425 Malignant tumor of colon Digestive System Diseases; Neoplasms
C0015625 BXGD001006 Fanconi Anemia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Hemic and Lymphatic Diseases
C0021051 BXGD001475 Immunologic Deficiency Syndromes Immune System Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0023467 BXGD001658 Leukemia, Myelocytic, Acute Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0033578 BXGD002408 Prostatic Neoplasms Neoplasms; Male Urogenital Diseases
C0202022 BXGD004065 Follicle stimulating hormone measurement
C0282687 BXGD006826 Hemorrhagic Fever, Ebola Infections
C0428402 BXGD008627 Human chorionic gonadotropin measurement
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0699790 BXGD009866 Colon Carcinoma Digestive System Diseases; Neoplasms
C0948008 BXGD011499 Ischemic stroke Nervous System Diseases; Cardiovascular Diseases
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1332977 BXGD012569 Childhood Leukemia Neoplasms
C1458155 BXGD013136 Mammary Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C1512409 BXGD013188 Hepatocarcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2985280 BXGD018223 Blood Protein Measurement
C3888194 BXGD019955 MIXED LINEAGE LEUKEMIA
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0005683 Quercetin 302.24
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein