Showing entry for MIXED LINEAGE LEUKEMIA


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD019955
Disease NameMIXED LINEAGE LEUKEMIA
Disease CUI IdC3888194
MeSH Codes   
Disease Class Name
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00139 BXGT003881 Kinesin-like protein KIF2A 3796 reviewed Cellular structure
O00255 BXGT003903 Menin 4221 reviewed
O14733 BXGT004087 Dual specificity mitogen-activated protein kinase kinase 7 5609 reviewed Kinase
O15054 BXGT004121 Lysine-specific demethylase 6B 23135 reviewed Epigenetic regulator
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43524 BXGT004599 Forkhead box protein O3 2309 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60341 BXGT004873 Lysine-specific histone demethylase 1A 23028 reviewed Epigenetic regulator
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O60885 BXGT004906 Bromodomain-containing protein 4 23476 reviewed Epigenetic regulator
O75164 BXGT005104 Lysine-specific demethylase 4A 9682 reviewed
O75475 BXGT005130 PC4 and SFRS1-interacting protein 11168 reviewed Signaling
O95342 BXGT005373 Bile salt export pump 8647 reviewed Transporter
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01106 BXGT005730 Myc proto-oncogene protein 4609 reviewed Transcription factor
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04271 BXGT006177 Protein S100-B 6285 reviewed Calcium-binding protein
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06493 BXGT006445 Cyclin-dependent kinase 1 983 reviewed Kinase
P06703 BXGT006477 Protein S100-A6 6277 reviewed Calcium-binding protein
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08473 BXGT006773 Neprilysin 4311 reviewed Enzyme
P08581 BXGT006794 Hepatocyte growth factor receptor 4233 reviewed Kinase
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09382 BXGT006882 Galectin-1 3956 reviewed Signaling
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P0DP23 BXGT007520 Calmodulin-1 808 reviewed
P0DP24 BXGT007521 Calmodulin-2 808 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10276 BXGT007553 Retinoic acid receptor alpha 5914 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10599 BXGT007583 Thioredoxin 7295 reviewed
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15036 BXGT008073 Protein C-ets-2 2114 reviewed Transcription factor
P15144 BXGT008087 Aminopeptidase N 290 reviewed Enzyme
P16070 BXGT008186 CD44 antigen 960 reviewed
P22083 BXGT008727 Alpha-(1,3)-fucosyltransferase 4 2526 reviewed Enzyme
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P26358 BXGT009104 DNA (cytosine-5)-methyltransferase 1 1786 reviewed Epigenetic regulator
P27707 BXGT009201 Deoxycytidine kinase 1633 reviewed Kinase
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P29375 BXGT009338 Lysine-specific demethylase 5A 5927 reviewed
P31260 BXGT009519 Homeobox protein Hox-A10 3206 reviewed
P33981 BXGT009744 Dual specificity protein kinase TTK 7272 reviewed Kinase
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P35658 BXGT009859 Nuclear pore complex protein Nup214 8021 reviewed Nucleic acid binding
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P41212 BXGT010235 Transcription factor ETV6 2120 reviewed Transcription factor
P41440 BXGT010261 Folate transporter 1 6573 reviewed Transporter
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P43652 BXGT010405 Afamin 173 reviewed Transporter
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P46527 BXGT010525 Cyclin-dependent kinase inhibitor 1B 1027 reviewed
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P56470 BXGT011173 Galectin-4 3960 reviewed Signaling
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P61964 BXGT011396 WD repeat-containing protein 5 11091 reviewed
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P84022 BXGT012027 Mothers against decapentaplegic homolog 3 4088 reviewed Transcription factor
Q00534 BXGT012533 Cyclin-dependent kinase 6 1021 reviewed Kinase
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01105 BXGT012569 Protein SET 6418 reviewed Enzyme modulator
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q02880 BXGT012677 DNA topoisomerase 2-beta 7155 reviewed
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q05516 BXGT012822 Zinc finger and BTB domain-containing protein 16 7704 reviewed Transcription factor
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13547 BXGT013373 Histone deacetylase 1 3065 reviewed Epigenetic regulator
Q13951 BXGT013407 Core-binding factor subunit beta 865 reviewed
Q14141 BXGT013447 Septin-6 23157 reviewed Enzyme modulator
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q14790 BXGT013505 Caspase-8 841 reviewed Enzyme
Q14839 BXGT013509 Chromodomain-helicase-DNA-binding protein 4 1108 reviewed
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q15022 BXGT013523 Polycomb protein SUZ12 23512 reviewed Nucleic acid binding
Q15125 BXGT013543 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 10682 reviewed Enzyme
Q15910 BXGT013612 Histone-lysine N-methyltransferase EZH2 2146 reviewed Epigenetic regulator
Q16512 BXGT013631 Serine/threonine-protein kinase N1 5585 reviewed Kinase
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha 3091 reviewed Transcription factor
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8TEK3 BXGT018822 Histone-lysine N-methyltransferase, H3 lysine-79 specific 84444 reviewed Epigenetic regulator
Q8WTS6 BXGT018986 Histone-lysine N-methyltransferase SETD7 80854 reviewed Epigenetic regulator
Q92993 BXGT019403 Histone acetyltransferase KAT5 10524 reviewed
Q93009 BXGT019455 Ubiquitin carboxyl-terminal hydrolase 7 7874 reviewed Enzyme
Q96KS0 BXGT019688 Egl nine homolog 2 112398 reviewed
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q96T88 BXGT019747 E3 ubiquitin-protein ligase UHRF1 29128 reviewed
Q99808 BXGT019964 Equilibrative nucleoside transporter 1 2030 reviewed Transporter
Q99828 BXGT019967 Calcium and integrin-binding protein 1 10519 reviewed
Q9C005 BXGT020207 Protein dpy-30 homolog 84661 reviewed
Q9H0U4 BXGT020443 Ras-related protein Rab-1B 81876 reviewed
Q9NR12 BXGT021174 PDZ and LIM domain protein 7 9260 reviewed Cellular structure
Q9NRW1 BXGT021194 Ras-related protein Rab-6B 51560 reviewed
Q9NXG6 BXGT021246 Transmembrane prolyl 4-hydroxylase 54681 reviewed
Q9UBB5 BXGT021649 Methyl-CpG-binding domain protein 2 8932 reviewed Epigenetic regulator
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UJ41 BXGT021723 Rab5 GDP/GTP exchange factor 27342 reviewed Enzyme modulator
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9Y223 BXGT022207 Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase 10020 reviewed Enzyme
Q9Y230 BXGT022208 RuvB-like 2 10856 reviewed
Q9Y2K7 BXGT022239 Lysine-specific demethylase 2A 22992 reviewed
Q9Y4I1 BXGT022278 Unconventional myosin-Va 4644 reviewed Cellular structure
P20138 BXGT023857 Myeloid cell surface antigen CD33 945 reviewed Receptor
Q13007 BXGT023883 Interleukin-24 11009 reviewed
Q15583 BXGT024027 Homeobox protein TGIF1 7050 reviewed Enzyme
P61204 BXGT024318 ADP-ribosylation factor 3 377 reviewed
P0DP25 BXGT024595 Calmodulin-3 808 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
Q8NEZ4 BXGT024850 Histone-lysine N-methyltransferase 2C 58508 reviewed
Q9NVA2 BXGT025757 Septin-11 55752 reviewed Enzyme modulator
P35251 BXGT025853 Replication factor C subunit 1 5981 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease