Showing entry for mRNA cap guanine-N7 methyltransferase


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT023017
Protein NamemRNA cap guanine-N7 methyltransferase
Uniport IdO43148
GeneRNMT
Gene Id8731
DomainPox_MCEL
Pfam PF03291  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03015 mRNA surveillance pathway
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006370 7-methylguanosine mRNA capping
Biological Process GO:1990830 cellular response to leukemia inhibitory factor
Biological Process GO:0006366 transcription by RNA polymerase II
molecular function GO:0004482 mRNA (guanine-N7-)-methyltransferase activity
molecular function GO:0003723 RNA binding
cellular component GO:0001650 fibrillar center
cellular component GO:0042025 host cell nucleus
cellular component GO:0005845 mRNA cap binding complex
cellular component GO:0031533 mRNA cap methyltransferase complex
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0043235 receptor complex
Reactome
Pathway Id Pathway Name
R-HSA-162587 HIV Life Cycle
R-HSA-162599 Late Phase of HIV Life Cycle
R-HSA-162906 HIV Infection
R-HSA-1643685 Disease
R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
R-HSA-167172 Transcription of the HIV genome
R-HSA-5663205 Infectious disease
R-HSA-72086 mRNA Capping
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE
R-HSA-8953854 Metabolism of RNA
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007959 BXGD000507 Charcot-Marie-Tooth Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0009402 BXGD000605 Colorectal Carcinoma Digestive System Diseases; Neoplasms
C0011195 BXGD000702 Dejerine-Sottas Disease (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0011882 BXGD000761 Diabetic Neuropathies Nervous System Diseases; Endocrine System Diseases
C0016057 BXGD001042 Fibrosarcoma Neoplasms
C0017636 BXGD001131 Glioblastoma Neoplasms
C0024198 BXGD001743 Lyme Disease Infections
C0027651 BXGD002009 Neoplasms Neoplasms
C0027708 BXGD002025 Nephroblastoma Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0027888 BXGD002056 Hereditary Motor and Sensory Neuropathies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0235025 BXGD004713 Peripheral motor neuropathy Nervous System Diseases
C0269102 BXGD006053 Endometrioma Female Urogenital Diseases and Pregnancy Complications
C0270911 BXGD006128 Charcot-Marie-Tooth Disease, Type Ia (disorder) Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270913 BXGD006130 Charcot-Marie-Tooth disease, Type 1C Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270914 BXGD006131 Hereditary Motor and Sensory-Neuropathy Type II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0270922 BXGD006134 Peripheral demyelinating neuropathy Immune System Diseases; Nervous System Diseases
C0270933 BXGD006135 Inflammatory neuropathy Nervous System Diseases
C0278595 BXGD006545 Adult Fibrosarcoma Neoplasms
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0334579 BXGD007120 Anaplastic astrocytoma Neoplasms
C0393808 BXGD008148 Charcot-Marie-Tooth disease, X-linked, 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393814 BXGD008149 Hereditary liability to pressure palsies Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0393818 BXGD008150 Congenital hypomyelinating neuropathy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393819 BXGD008151 Polyradiculoneuropathy, Chronic Inflammatory Demyelinating Immune System Diseases; Nervous System Diseases
C0432185 BXGD008730 Aplasia of muscle Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0520679 BXGD009101 Sleep Apnea, Obstructive Respiratory Tract Diseases; Nervous System Diseases
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0598589 BXGD009667 Inherited neuropathies Nervous System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0751036 BXGD010299 Hereditary Motor and Sensory Neuropathy Type I Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751964 BXGD010655 Multiple Sclerosis, Primary Progressive Immune System Diseases; Nervous System Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1536148 BXGD013338 Chocolate cyst of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2930619 BXGD017890 Sex Differentiation Disorders Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000436 Glycerol 92.09
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein