adisease

Showing entry for Lyme Disease

General Disease Information
BXGD Id	BXGD001743
Disease Name	Lyme Disease
Disease CUI Id	C0024198
MeSH Codes	C01
Disease Class Name	Infections
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0050117
Disease Ontology Class Name	disease by infectious agent
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
O60885	BXGT004906	Bromodomain-containing protein 4	23476	reviewed	Epigenetic regulator
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01911	BXGT005816	HLA class II histocompatibility antigen, DRB1-15 beta chain	3123	reviewed	Immune response
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02751	BXGT005943	Fibronectin	2335	reviewed	Signaling
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05230	BXGT006344	Fibroblast growth factor 1	2246	reviewed	Signaling
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05412	BXGT006354	Transcription factor AP-1	3725	reviewed	Transcription factor
P06733	BXGT006490	Alpha-enolase	2023	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P09104	BXGT006856	Gamma-enolase	2026	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10301	BXGT007556	Ras-related protein R-Ras	6237	reviewed	Enzyme modulator
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11226	BXGT007675	Mannose-binding protein C	4153	reviewed	Receptor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13645	BXGT007936	Keratin, type I cytoskeletal 10	3858	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P19320	BXGT008470	Vascular cell adhesion protein 1	7412	reviewed
P19367	BXGT008476	Hexokinase-1	3098	reviewed	Kinase
P19438	BXGT008480	Tumor necrosis factor receptor superfamily member 1A	7132	reviewed
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	4790	reviewed	Transcription factor
P20339	BXGT008565	Ras-related protein Rab-5A	5868	reviewed
P23219	BXGT008837	Prostaglandin G/H synthase 1	5742	reviewed	Enzyme
P25942	BXGT009079	Tumor necrosis factor receptor superfamily member 5	958	reviewed
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P28907	BXGT009301	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	952	reviewed	Enzyme
P29016	BXGT009304	T-cell surface glycoprotein CD1b	910	reviewed
P30626	BXGT009450	Sorcin	6717	reviewed
P31948	BXGT009590	Stress-induced-phosphoprotein 1	10963	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P49411	BXGT010703	Elongation factor Tu, mitochondrial	7284	reviewed	Enzyme
P49902	BXGT010758	Cytosolic purine 5'-nucleotidase	22978	reviewed	Enzyme
P51946	BXGT010907	Cyclin-H	902	reviewed	Enzyme modulator
P54756	BXGT011074	Ephrin type-A receptor 5	2044	reviewed	Kinase
P68104	BXGT011575	Elongation factor 1-alpha 1	1915	reviewed	Enzyme
Q06609	BXGT012884	DNA repair protein RAD51 homolog 1	5888	reviewed
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13501	BXGT013365	Sequestosome-1	8878	reviewed
Q14103	BXGT013439	Heterogeneous nuclear ribonucleoprotein D0	3184	reviewed
Q14118	BXGT013444	Dystroglycan	1605	reviewed	Receptor
Q14204	BXGT013456	Cytoplasmic dynein 1 heavy chain 1	1778	reviewed	Enzyme
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15185	BXGT013549	Prostaglandin E synthase 3	10728	reviewed	Chaperone
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16853	BXGT013683	Membrane primary amine oxidase	8639	reviewed
Q5VWK5	BXGT015891	Interleukin-23 receptor	149233	reviewed	Signaling
Q8IU54	BXGT018331	Interferon lambda-1	282618	reviewed
Q8IXH7	BXGT018359	Negative elongation factor C/D	51497	reviewed
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q96J66	BXGT019680	ATP-binding cassette sub-family C member 11	85320	reviewed	Transporter
Q99467	BXGT019923	CD180 antigen	4064	reviewed	Receptor
Q99623	BXGT019941	Prohibitin-2	11331	reviewed
Q99653	BXGT019945	Calcineurin B homologous protein 1	11261	reviewed
Q9BX66	BXGT020158	Sorbin and SH3 domain-containing protein 1	10580	reviewed
Q9BY08	BXGT020177	Emopamil-binding protein-like	84650	reviewed	Enzyme
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9GZR1	BXGT020423	Sentrin-specific protease 6	26054	reviewed	Enzyme
Q9GZX6	BXGT020428	Interleukin-22	50616	reviewed
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NR97	BXGT021182	Toll-like receptor 8	51311	reviewed
Q9NYK1	BXGT021258	Toll-like receptor 7	51284	reviewed
Q9UIQ6	BXGT021721	Leucyl-cystinyl aminopeptidase	4012	reviewed	Enzyme
Q9Y3D8	BXGT022258	Adenylate kinase isoenzyme 6	102157402	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
O43148	BXGT023017	mRNA cap guanine-N7 methyltransferase	8731	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
P00395	BXGT023596	Cytochrome c oxidase subunit 1	4512	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}