Showing entry for Nucleic acid dioxygenase ALKBH1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT024292
Protein NameNucleic acid dioxygenase ALKBH1
Uniport IdQ13686
GeneALKBH1
Gene Id8846
Domain2OG-FeII_Oxy_2
Pfam PF13532  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0048589 developmental growth
Biological Process GO:0006307 DNA dealkylation involved in DNA repair
Biological Process GO:0080111 DNA demethylation
Biological Process GO:0006281 DNA repair
Biological Process GO:0001701 in utero embryonic development
Biological Process GO:0043524 negative regulation of neuron apoptotic process
Biological Process GO:0001764 neuron migration
Biological Process GO:0031175 neuron projection development
Biological Process GO:0070989 oxidative demethylation
Biological Process GO:0035513 oxidative RNA demethylation
Biological Process GO:0001890 placenta development
Biological Process GO:0070129 regulation of mitochondrial translation
Biological Process GO:0006448 regulation of translational elongation
Biological Process GO:0006446 regulation of translational initiation
Biological Process GO:0042245 RNA repair
Biological Process GO:1990983 tRNA demethylation
Biological Process GO:0002101 tRNA wobble cytosine modification
molecular function GO:0103053 1-ethyladenine demethylase activity
molecular function GO:0016706 2-oxoglutarate-dependent dioxygenase activity
molecular function GO:0042056 chemoattractant activity
molecular function GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity
molecular function GO:0008198 ferrous iron binding
molecular function GO:0070579 methylcytosine dioxygenase activity
molecular function GO:0035516 oxidative DNA demethylase activity
molecular function GO:0035515 oxidative RNA demethylase activity
molecular function GO:0000049 tRNA binding
molecular function GO:1990984 tRNA demethylase activity
cellular component GO:0005783 endoplasmic reticulum
cellular component GO:0005739 mitochondrion
cellular component GO:0005719 nuclear euchromatin
cellular component GO:0005654 nucleoplasm
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0001883 BXGD000086 Airway Obstruction Respiratory Tract Diseases
C0003850 BXGD000225 Arteriosclerosis Cardiovascular Diseases
C0004153 BXGD000260 Atherosclerosis Cardiovascular Diseases
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0005684 BXGD000319 Malignant neoplasm of urinary bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0005695 BXGD000323 Bladder Neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007097 BXGD000424 Carcinoma Neoplasms
C0007138 BXGD000446 Carcinoma, Transitional Cell Neoplasms
C0007222 BXGD000454 Cardiovascular Diseases Cardiovascular Diseases
C0011881 BXGD000760 Diabetic Nephropathy Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0013295 BXGD000812 Duodenal Ulcer Digestive System Diseases
C0014070 BXGD000887 Encephalomyelitis Infections; Nervous System Diseases
C0016085 BXGD001047 Filariasis Infections
C0017636 BXGD001131 Glioblastoma Neoplasms
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0023418 BXGD001642 leukemia Neoplasms
C0024299 BXGD001758 Lymphoma Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0024623 BXGD001791 Malignant neoplasm of stomach Digestive System Diseases; Neoplasms
C0025303 BXGD001858 Meningococcal Infections Infections
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027813 BXGD002041 Neuritis Nervous System Diseases
C0028840 BXGD002089 Ocular Hypertension Eye Diseases
C0029927 BXGD002182 Ovarian Cysts Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030920 BXGD002263 Peptic Ulcer Digestive System Diseases
C0042974 BXGD003019 von Willebrand Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Hemic and Lymphatic Diseases
C0154947 BXGD003760 Anatomical narrow angle glaucoma Eye Diseases
C0242379 BXGD005157 Malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0278878 BXGD006609 Adult Glioblastoma Neoplasms
C0278996 BXGD006621 Malignant Head and Neck Neoplasm Neoplasms
C0280474 BXGD006748 Childhood Glioblastoma Neoplasms
C0374997 BXGD007967 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
C0376358 BXGD007992 Malignant neoplasm of prostate Neoplasms; Male Urogenital Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0600139 BXGD009695 Prostate carcinoma Neoplasms; Male Urogenital Diseases
C0684249 BXGD009790 Carcinoma of lung Neoplasms; Respiratory Tract Diseases
C0699791 BXGD009867 Stomach Carcinoma Digestive System Diseases; Neoplasms
C0699885 BXGD009869 Carcinoma of bladder Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0740391 BXGD009987 Middle Cerebral Artery Occlusion Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Cardiovascular Diseases
C0857070 BXGD011134 Chronic open angle glaucoma Eye Diseases
C1269955 BXGD012005 Tumor Cell Invasion
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1306460 BXGD012362 Primary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C1621958 BXGD013468 Glioblastoma Multiforme Neoplasms
C2939419 BXGD018178 Secondary Neoplasm Pathological Conditions, Signs and Symptoms; Neoplasms
C3875265 BXGD019873 Febrile urinary tract infection Female Urogenital Diseases and Pregnancy Complications; Infections; Male Urogenital Diseases
C3887461 BXGD019876 Head and Neck Carcinoma Neoplasms
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0000434 Ethanol 46.07
BXGC0002485 2-Oxopentanedioic acid 146.1
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein