Showing entry for Ocular Hypertension


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD002089
Disease NameOcular Hypertension
Disease CUI IdC0028840
MeSH Codes C11  
Disease Class NameEye Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O43557 BXGT004600 Tumor necrosis factor ligand superfamily member 14 8740 reviewed Signaling
O60313 BXGT004871 Dynamin-like 120 kDa protein, mitochondrial 4976 reviewed Enzyme modulator
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00918 BXGT005690 Carbonic anhydrase 2 760 reviewed
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02746 BXGT005938 Complement C1q subcomponent subunit B 713 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P05412 BXGT006354 Transcription factor AP-1 3725 reviewed Transcription factor
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07996 BXGT006710 Thrombospondin-1 7057 reviewed
P08151 BXGT006731 Zinc finger protein GLI1 2735 reviewed
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08908 BXGT006837 5-hydroxytryptamine receptor 1A 3350 reviewed G-protein coupled receptor
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P15121 BXGT008083 Aldo-keto reductase family 1 member B1 231 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P17252 BXGT008294 Protein kinase C alpha type 5578 reviewed Kinase
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35916 BXGT009881 Vascular endothelial growth factor receptor 3 2324 reviewed Kinase
P38936 BXGT010074 Cyclin-dependent kinase inhibitor 1 1026 reviewed
P43116 BXGT010357 Prostaglandin E2 receptor EP2 subtype 5732 reviewed G-protein coupled receptor
P57764 BXGT011217 Gasdermin-D 79792 reviewed
P60174 BXGT011294 Triosephosphate isomerase 7167 reviewed Enzyme
Q02750 BXGT012662 Dual specificity mitogen-activated protein kinase kinase 1 5604 reviewed Kinase
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q02790 BXGT012672 Peptidyl-prolyl cis-trans isomerase FKBP4 2288 reviewed Enzyme
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q13451 BXGT013356 Peptidyl-prolyl cis-trans isomerase FKBP5 2289 reviewed Enzyme
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q16611 BXGT013644 Bcl-2 homologous antagonist/killer 578 reviewed Signaling
Q16678 BXGT013656 Cytochrome P450 1B1 1545 reviewed Enzyme
Q96FE5 BXGT019657 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 84894 reviewed Receptor
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q99835 BXGT019969 Smoothened homolog 6608 reviewed G-protein coupled receptor
Q99972 BXGT019979 Myocilin 4653 reviewed Cellular structure
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H816 BXGT020494 5' exonuclease Apollo 64858 reviewed
Q9HBA0 BXGT020516 Transient receptor potential cation channel subfamily V member 4 59341 reviewed Ion channel
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q92847 BXGT022673 Growth hormone secretagogue receptor type 1 2693 reviewed G-protein coupled receptor
Q13686 BXGT024292 Nucleic acid dioxygenase ALKBH1 8846 reviewed
P02489 BXGT026168 Alpha-crystallin A chain 1409 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease