acompound

Showing entry for 2,6-Dihydroxybenzoic acid

General Compound Information
BXGC Id	BXGC0000503
Compound Name	2,6-Dihydroxybenzoic acid
Structure
Formula	C7H6O4
InchiKey	AKEUNCKRJATALU-UHFFFAOYSA-N
SMILES	OC(=O)C1=C(O)C=CC=C1O
Inchi	InChI=1S/C7H6O4/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,8-9H,(H,10,11)
IUPAC	2,6-dihydroxybenzoic acid
Molecular Weight	154.12
Pubchem Id	9338
Chembl Id	CHEMBL454808

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

GRE

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q60GU1	BXGT016013	Thermophilic reversible gamma-resorcylate decarboxylase	unreviewed		-	-	-	-	-
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	CA2	-	3000000	-	-	-

Binding DB

92712

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT008271	Prolyl 4-hydroxylase subunit alpha-1	reviewed		P4HA1	1100000	-	-	-
reviewed	BXGT010364	Carbonic anhydrase 7	reviewed		CA7	6600	-	-	-
reviewed	BXGT005690	Carbonic anhydrase 2	reviewed		CA2	5200	-	-	-
reviewed	BXGT005689	Carbonic anhydrase 1	reviewed		CA1	5700	-	-	-
reviewed	BXGT021769	Carbonic anhydrase 14	reviewed		CA14	6500	-	-	-
reviewed	BXGT004601	Carbonic anhydrase 12	reviewed		CA12	7200	-	-	-
reviewed	BXGT013670	Carbonic anhydrase 9	reviewed		CA9	5900	-	-	-

CHEMBL

CHEMBL454808

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P43166	BXGT010364	Carbonic anhydrase 7	reviewed	-	CA7	Ki	'='	6600	nM
P09917	BXGT006941	Arachidonate 5-lipoxygenase	reviewed	Enzyme	ALOX5	Inhibition	'='	38	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	95	%
P08254	BXGT006758	Stromelysin-1	reviewed	Enzyme	MMP3	Inhibition	'='	-4	%
P29477	BXGT009355	Nitric oxide synthase, inducible	reviewed	-	Nos2	Inhibition	'='	17	%
P22894	BXGT008815	Neutrophil collagenase	reviewed	Enzyme	MMP8	Inhibition	'='	-5	%
P03956	BXGT006120	Interstitial collagenase	reviewed	Enzyme	MMP1	Inhibition	'='	0	%
P08253	BXGT006757	72 kDa type IV collagenase	reviewed	Enzyme	MMP2	Inhibition	'='	-6	%
O43570	BXGT004601	Carbonic anhydrase 12	reviewed	-	CA12	Ki	'='	7200	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Inhibition	'='	15	%
Q16790	BXGT013670	Carbonic anhydrase 9	reviewed	-	CA9	Ki	'='	5900	nM
Q9ULX7	BXGT021769	Carbonic anhydrase 14	reviewed	-	CA14	Ki	'='	6500	nM
P00915	BXGT005689	Carbonic anhydrase 1	reviewed	-	CA1	Ki	'='	5700	nM
P14780	BXGT008053	Matrix metalloproteinase-9	reviewed	Enzyme	MMP9	Inhibition	'='	-11	%
P00918	BXGT005690	Carbonic anhydrase 2	reviewed	-	CA2	Ki	'='	5200	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00120	Evening primrose	Oenothera biennis	Herbs and Spices
BXGF00121	Olive	Olea europaea	Vegetables
BXGF00248	Beer		Beverages
BXGF00981	Flacourtia jangomas	Flacourtia jangomas	Medicinal Plant
BXGF01126	Polygonum cuspidatum	Polygonum cuspidatum	Medicinal Plant
BXGF01187	Onobrychis arenaria	Onobrychis arenaria	Others
BXGF01223	Eria mollis	Eria mollis	Others
BXGF01302	Dysoxylum cumingianum	Dysoxylum cumingianum	Others
BXGF01344	Psychotria stachyoides	Psychotria stachyoides	Others
BXGF01391	Dodonaea viscosa	Dodonaea viscosa	Medicinal Plant
BXGF01568	Teucrium yemense	Teucrium yemense	Others
BXGF01641	Neobalanocarpus heimii	Neobalanocarpus heimii	Others
BXGF01683	Aconitum tasiromontanum	Aconitum tasiromontanum	Others
BXGF01764	Dendriopoterium menendezii	Dendriopoterium menendezii	Others
BXGF01794	Adansonia grandidieri	Adansonia grandidieri	Human Edible Plant
BXGF01812	Physalis alkekengi	Physalis alkekengi	Medicinal Plant
BXGF01836	Aphyllocladus denticulatus	Aphyllocladus denticulatus	Others
BXGF01850	Bassia muricata	Bassia muricata	Medicinal Plant
BXGF01947	Senecio subdentatus	Senecio subdentatus	Others
BXGF02006	Aconitum seravschanicum	Aconitum seravschanicum	Others
BXGF03485	Justicia secunda	Justicia secunda	Others
BXGF04064	Rumex japonicus	Rumex japonicus	Medicinal Plant
BXGF04205	Aster sedifolius	Aster sedifolius	Others
BXGF05018	Lavandula vera	Lavandula vera	Medicinal Plant
BXGF06011	Enceliopsis argophylla	Enceliopsis argophylla	Others
BXGF06281	Miliusa velutina	Miliusa velutina	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}