acompound

Showing entry for Putrescine

General Compound Information
BXGC Id	BXGC0000985
Compound Name	Putrescine
Structure
Formula	C4H12N2
InchiKey	KIDHWZJUCRJVML-UHFFFAOYSA-N
SMILES	NCCCCN
Inchi	InChI=1S/C4H12N2/c5-3-1-2-4-6/h1-6H2
IUPAC	butane-1,4-diamine
Molecular Weight	88.15
Pubchem Id	1045
Chembl Id	CHEMBL46257

Targets of Information Source

DrugBank

DB01917

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P11926	BXGT007760	Ornithine decarboxylase	reviewed	Enzyme	ODC1	experimental	-
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	reviewed	Enzyme	AMD1	experimental	-
P31133	BXGT009509	Putrescine-binding periplasmic protein	reviewed	-	potF	experimental	-
P08588	BXGT006795	Beta-1 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB1	experimental	-
P07550	BXGT006636	Beta-2 adrenergic receptor	reviewed	G-protein coupled receptor	ADRB2	experimental	-

PDB

PUT

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P31133	BXGT009509	Putrescine-binding periplasmic protein	reviewed	potF	-	-	-	2000	-
P07805	BXGT006676	Ornithine decarboxylase	reviewed		-	-	-	-	-
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	reviewed	AMD1	Enzyme	-	-	-	-
P19623	BXGT008503	Spermidine synthase	reviewed	SRM	Enzyme	-	-	-	-
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	reviewed	AMD1	Enzyme	-	-	-	2000
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	reviewed	AMD1	Enzyme	-	-	-	10000
Q9I6J1	BXGT020769	Putrescine-binding periplasmic protein SpuD	reviewed	spuD	-	-	-	3	-
Q8II73	BXGT018273	Spermidine synthase	unreviewed	PF3D7_1129000	-	-	-	-	-
O32323	BXGT004437	Homospermidine synthase	reviewed	hss	-	-	-	-	-
P42588	BXGT010320	Putrescine aminotransferase	reviewed	patA	-	-	-	-	-
G7ITU5	BXGT003543	N-carbamoylputrescine amidohydrolase, putative	unreviewed	11406591	-	-	-	-	-
Q587A7	BXGT015209	S-adenosylmethionine decarboxylase proenzyme	unreviewed	Tb927.6.4410	-	-	-	-	-
Q587B3	BXGT015210	S-adenosylmethionine decarboxylase proenzyme-like, putative	unreviewed	Tb927.6.4470	-	-	-	-	-
A5HNV6	BXGT001316	Inactive S-adenosylmethionine decarboxylase prozyme	reviewed		-	-	-	-	-
Q88NI1	BXGT017723	Methyl-accepting chemotaxis protein McpU	reviewed	mcpU	-	-	-	2000	-
Q31QK9	BXGT025342	Polyamine aminopropyltransferase	reviewed	speE	-	-	-	-	-
P49366	BXGT025175	Deoxyhypusine synthase	reviewed	DHPS	-	-	-	-	-

Binding DB

50009385

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006853	Ornithine decarboxylase	reviewed		Odc1	3300000	-	-	-
reviewed	BXGT006853	Ornithine decarboxylase	reviewed		Odc1	3500000	-	-	-

CHEMBL

CHEMBL46257

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	-	-	-
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
P19838	BXGT008526	Nuclear factor NF-kappa-B p105 subunit	reviewed	Transcription factor	NFKB1	Potency	'='	28183	nM
P17707	BXGT008331	S-adenosylmethionine decarboxylase proenzyme	reviewed	Enzyme	AMD1	Ka	'='	16	uM
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	-	-	-
P09057	BXGT006853	Ornithine decarboxylase	reviewed	-	Odc1	Ki	'='	3300000	nM
P49798	BXGT010745	Regulator of G-protein signaling 4	reviewed	Enzyme modulator	RGS4	Potency	-	7519	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	-	-	-
P09057	BXGT006853	Ornithine decarboxylase	reviewed	-	Odc1	TIME	'='	55	hr
P09057	BXGT006853	Ornithine decarboxylase	reviewed	-	Odc1	Activity	'='	90	-
Q9TTK6	BXGT021624	Membrane primary amine oxidase	reviewed	-	AOC3	Fluorescence intensity	'='	2	-
P09057	BXGT006853	Ornithine decarboxylase	reviewed	-	Odc1	Ki	'='	3500000	nM
Q9H015	BXGT020432	Solute carrier family 22 member 4	reviewed	Transporter	SLC22A4	Activity	-	-	-
P14100	BXGT007985	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	reviewed	-	PDE1A	IC50	'>'	500000	nM
Q01061	BXGT012562	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	reviewed	-	PDE1B	IC50	'>'	500000	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	-	-	-
O15648	BXGT004185	ATP-dependent 6-phosphofructokinase	reviewed	-	pfk	Potency	-	37933	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00006	Garden onion	Allium cepa	Vegetables
BXGF00013	Dill	Anethum graveolens	Herbs and Spices
BXGF00022	Oat	Avena sativa	Cereals and cereal products
BXGF00034	Broccoli	Brassica oleracea var. italica	Vegetables
BXGF00036	Turnip	Brassica rapa var. rapa	Herbs and Spices
BXGF00059	Arabica coffee	Coffea arabica	Coffee and coffee products
BXGF00065	Cucumber	Cucumis sativus	Gourds
BXGF00072	Wild carrot	Daucus carota	Vegetables
BXGF00085	Soy bean	Glycine max	Soy
BXGF00088	Barley	Hordeum vulgare	Cereals and cereal products
BXGF00105	Apple	Malus pumila	Fruits
BXGF00129	Parsnip	Pastinaca sativa	Vegetables
BXGF00141	Common pea	Pisum sativum	Pulses
BXGF00148	Almond	Prunus dulcis	Nuts
BXGF00153	Radish	Raphanus sativus	Vegetables
BXGF00162	Red raspberry	Rubus idaeus	Fruits
BXGF00169	Rye	Secale cereale	Cereals and cereal products
BXGF00170	Sesame	Sesamum orientale	Herbs and Spices
BXGF00171	Garden tomato	Solanum lycopersicum	Vegetables
BXGF00175	Potato	Solanum tuberosum	Vegetables
BXGF00178	Spinach	Spinacia oleracea	Vegetables
BXGF00187	Common wheat	Triticum aestivum	Cereals and cereal products
BXGF00205	Corn	Zea mays	Cereals and cereal products
BXGF00225	Swiss chard	Beta vulgaris ssp. cicla	Vegetables
BXGF00230	Carrot	Daucus carota ssp. sativus	Vegetables
BXGF00246	Red beetroot	Beta vulgaris var. rubra	Vegetables
BXGF00400	French plantain	Musa X paradisiaca	Fruits
BXGF00519	Wheat	Triticum	Cereals and cereal products
BXGF00830	Yellow bell pepper	Capsicum annuum	Vegetables
BXGF00831	Orange bell pepper	Capsicum annuum	Vegetables
BXGF00832	Red bell pepper	Capsicum annuum	Vegetables
BXGF00834	Yellow wax bean	Phaseolus vulgaris	Pulses
BXGF00836	Saskatoon berry	Amelanchier alnifolia	Fruits
BXGF00837	Nanking cherry	Prunus tomentosa	Fruits
BXGF00839	White cabbage	Brassica oleracea L. var. capitata L. f. alba DC.	Vegetables
BXGF01848	Pyrus pyraster	Pyrus pyraster	Medicinal Plant
BXGF02094	Astragalus oxyphysus	Astragalus oxyphysus	Others
BXGF02497	Hydrodictyon reticulatum	Hydrodictyon reticulatum	Human Edible Plant
BXGF02801	Senecio candollei	Senecio candollei	Others
BXGF02849	Polyscias scutellaria	Polyscias scutellaria	Medicinal Plant
BXGF02871	Centaurea glastifolia	Centaurea glastifolia	Others
BXGF02902	Grindelia havardii	Grindelia havardii	Others
BXGF02918	Nephelium maingayi	Nephelium maingayi	Human Edible Plant
BXGF02934	Galanthus nivalis	Galanthus nivalis	Medicinal Plant
BXGF02954	Euphorbia armena	Euphorbia armena	Others
BXGF03176	Capparis masaikai	Capparis masaikai	Medicinal Plant
BXGF03221	Nectandra pichurim	Nectandra pichurim	Human Edible Plant
BXGF03496	Pityrogramma tartarea	Pityrogramma tartarea	Others
BXGF04659	Phyllanthus emblica	Phyllanthus emblica	Medicinal Plant
BXGF04820	Panax ginseng	Panax ginseng	0
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant
BXGF05203	Chlamydomonas reinhardtii	Chlamydomonas reinhardtii	Others
BXGF05296	Canavalia gladiata	Canavalia gladiata	Medicinal Plant
BXGF06109	Cuscuta reflexa	Cuscuta reflexa	Medicinal Plant
BXGF06113	Plantago depressa	Plantago depressa	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}