Showing entry for Lead


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0002702
Compound NameLead
Structure
FormulaPb
InchiKeyRVPVRDXYQKGNMQ-UHFFFAOYSA-N
SMILES[Pb++]
InchiInChI=1S/Pb/q+2
IUPAC?f2-lead(2+) ion
Molecular Weight207.2
Pubchem Id73212
Chembl Id
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB PB
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed APEX1 - - - - -
O97148 BXGT005432 G-protein coupled receptor Mth reviewed mth - - - - -
Q8RQE8 BXGT018733 DNA-directed RNA polymerase subunit beta' reviewed rpoC - - - - -
Q8U3L0 BXGT018891 Thermostable carboxypeptidase 1 reviewed PF0456 - - - - -
P07463 BXGT006628 Calmodulin reviewed CAM - - - - -
P05373 BXGT006352 Delta-aminolevulinic acid dehydratase reviewed HEM2 - - - - -
P0AB91 BXGT007223 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive reviewed aroG - - - - -
P21513 BXGT008657 Ribonuclease E reviewed rne - - - - -
O84835 BXGT005230 Ribonucleoside-diphosphate reductase subunit beta reviewed nrdB - - - - -
O54788 BXGT004732 DNA fragmentation factor subunit beta reviewed Dffb - - - - -
P0A6D0 BXGT007047 Arginine repressor reviewed argR - - - - -
P35844 BXGT009875 Oxysterol-binding protein homolog 4 reviewed KES1 - - - - -
Q9X0M7 BXGT022069 Methyl-accepting chemotaxis protein 2 reviewed mcp2 - - - - -
P03680 BXGT006097 DNA polymerase reviewed 2 - - - - -
P07108 BXGT006551 Acyl-CoA-binding protein reviewed DBI Enzyme modulator - - - -
P9WIB9 BXGT012315 Secreted chorismate mutase reviewed Rv1885c - - - - -
Q9D020 BXGT020254 Cytosolic 5'-nucleotidase 3A reviewed Nt5c3a - - - - -
A0MTA1 BXGT000846 DNA-(apurinic or apyrimidinic site) lyase reviewed apex1 - - - - -
P43403 BXGT010385 Tyrosine-protein kinase ZAP-70 reviewed ZAP70 Kinase - - - -
P22830 BXGT008809 Ferrochelatase, mitochondrial reviewed FECH Enzyme - - - -
O13828 BXGT004062 mRNA decapping complex subunit 2 reviewed dcp2 - - - - -
P0DP23 BXGT007520 Calmodulin-1 reviewed CALM1 - - - - -
Q93YN9 BXGT019546 Inositol-pentakisphosphate 2-kinase reviewed IPK1 - - - - -
Q96JH8 BXGT019683 Ras-associating and dilute domain-containing protein reviewed RADIL - - - - -
P72412 BXGT011710 Outer membrane heme receptor ShuA unreviewed shuA - - - - -
P38505 BXGT010046 Calcium-binding protein reviewed - - - - -
Q9WYN9 BXGT021993 Protein-glutamate methylesterase/protein-glutamine glutaminase reviewed cheB - - - - -
P05696 BXGT006379 Protein kinase C alpha type reviewed Prkca - - - - -
P33981 BXGT009744 Dual specificity protein kinase TTK reviewed TTK Kinase - - - -
C3TPM7 BXGT002451 Elongation factor Ts unreviewed tsf - - - - -
Q06787 BXGT012890 Synaptic functional regulator FMR1 reviewed FMR1 Nucleic acid binding - - - -
Q51817 BXGT014968 Lys-gingipain W83 reviewed kgp - - - - -
A8JF99 BXGT001705 ARF-like small GTPase unreviewed BBS3B - - - - -
A8JEA1 BXGT001704 Bardet-biedl syndrome 1 protein unreviewed BBS1 - - - - -
Q88435 BXGT017692 Nucleoprotein reviewed NP - - - - -
A8NI40 BXGT001714 Glycosyl hydrolase family 62 protein unreviewed CC1G_01577 - - - - -
Q1LKZ5 BXGT013819 Transcriptional regulator, MerR-family unreviewed pbrR2 - - - - -
D4GTL2 BXGT002927 Malate synthase reviewed aceB - - - - -
P46096 BXGT010506 Synaptotagmin-1 reviewed Syt1 - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00006 Garden onion Allium cepa Vegetables
BXGF00011 Cashew nut Anacardium occidentale Nuts
BXGF00013 Dill Anethum graveolens Herbs and Spices
BXGF00015 Wild celery Apium graveolens Herbs and Spices
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00018 Horseradish Armoracia rusticana Herbs and Spices
BXGF00020 Mugwort Artemisia vulgaris Herbs and Spices
BXGF00021 Asparagus Asparagus officinalis Vegetables
BXGF00034 Broccoli Brassica oleracea var. italica Vegetables
BXGF00036 Turnip Brassica rapa var. rapa Herbs and Spices
BXGF00040 Pepper (C. annuum) Capsicum annuum Vegetables
BXGF00048 Endive Cichorium endivia Vegetables
BXGF00051 Ceylon cinnamon Cinnamomum verum Herbs and Spices
BXGF00057 Sweet orange Citrus sinensis Fruits
BXGF00062 Common hazelnut Corylus avellana Nuts
BXGF00064 Muskmelon Cucumis melo Gourds
BXGF00065 Cucumber Cucumis sativus Gourds
BXGF00072 Wild carrot Daucus carota Vegetables
BXGF00085 Soy bean Glycine max Soy
BXGF00093 Black walnut Juglans nigra Nuts
BXGF00095 Lettuce Lactuca sativa Vegetables
BXGF00101 Flaxseed Linum usitatissimum Herbs and Spices
BXGF00105 Apple Malus pumila Fruits
BXGF00115 Bitter gourd Momordica charantia Gourds
BXGF00125 Rice Oryza sativa Cereals and cereal products
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00131 Parsley Petroselinum crispum Herbs and Spices
BXGF00133 Lima bean Phaseolus lunatus Pulses
BXGF00134 Common bean Phaseolus vulgaris Pulses
BXGF00135 Date Phoenix dactylifera Fruits
BXGF00140 Pistachio Pistacia vera Nuts
BXGF00141 Common pea Pisum sativum Pulses
BXGF00147 European plum Prunus domestica Fruits
BXGF00148 Almond Prunus dulcis Nuts
BXGF00149 Peach Prunus persica Fruits
BXGF00152 Pear Pyrus communis Fruits
BXGF00153 Radish Raphanus sativus Vegetables
BXGF00154 Garden rhubarb Rheum rhabarbarum Vegetables
BXGF00155 Blackcurrant Ribes nigrum Fruits
BXGF00156 Redcurrant Ribes rubrum Fruits
BXGF00161 Cloudberry Rubus chamaemorus Fruits
BXGF00171 Garden tomato Solanum lycopersicum Vegetables
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
BXGF00174 Eggplant Solanum melongena Vegetables
BXGF00175 Potato Solanum tuberosum Vegetables
BXGF00178 Spinach Spinacia oleracea Vegetables
BXGF00181 Dandelion Taraxacum officinale Herbs and Spices
BXGF00187 Common wheat Triticum aestivum Cereals and cereal products
BXGF00192 American cranberry Vaccinium macrocarpon Fruits
BXGF00193 Bilberry Vaccinium myrtillus Fruits
BXGF00199 Gram bean Vigna mungo Pulses
BXGF00200 Mung bean Vigna radiata Pulses
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00205 Corn Zea mays Cereals and cereal products
BXGF00230 Carrot Daucus carota ssp. sativus Vegetables
BXGF00246 Red beetroot Beta vulgaris var. rubra Vegetables
BXGF00265 Allspice Pimenta dioica Herbs and Spices
BXGF00289 Giant butterbur Petasites japonicus Vegetables
BXGF00291 Butternut Juglans cinerea Nuts
BXGF00310 Coconut Cocos nucifera Fruits
BXGF00349 Irish moss Chondrus crispus Aquatic foods
BXGF00394 Common persimmon Diospyros virginiana Fruits
BXGF00400 French plantain Musa X paradisiaca Fruits
BXGF00481 Black-eyed pea Vigna unguiculata ssp. unguiculata Pulses
BXGF00803 Cabbage Brassica oleracea var. capitata Vegetables
BXGF00826 Sunburst squash (pattypan squash) Cucurbita pepo var. clypeata Gourds
BXGF00827 Green zucchini Cucurbita pepo var. cylindrica Gourds
BXGF00828 Yellow zucchini Cucurbita pepo var. cylindrica Gourds
BXGF00829 Green bell pepper Capsicum annuum Vegetables
BXGF00830 Yellow bell pepper Capsicum annuum Vegetables
BXGF00831 Orange bell pepper Capsicum annuum Vegetables
BXGF00832 Red bell pepper Capsicum annuum Vegetables
BXGF00833 Italian sweet red pepper Capsicum annuum Vegetables
BXGF00838 Japanese pumpkin Cucurbita maxima Gourds
BXGF00839 White cabbage Brassica oleracea L. var. capitata L. f. alba DC. Vegetables
BXGF00840 Romaine lettuce Lactuca sativa L. var. longifolia Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease