Showing entry for Synaptic functional regulator FMR1


　 　 　 　 　 　 　 　 　 　 　 　
General Target Information
BXGT IdBXGT012890
Protein NameSynaptic functional regulator FMR1
Uniport IdQ06787
GeneFMR1
Gene Id2332
DomainAgenet; FXMRP1_C_core; FXMR_C2; KH_1; KH_9; Tudor_FRX1
Pfam PF05641   PF16098   PF12235   PF00013   PF17904   PF18336  
OrganismHomo sapiens (Human)
Target protein  affiliated  biological  pathways
KEGG
Class Subclass KEGG Id Pathway Name
2. Genetic Information Processing 2.2 Translation hsa03013 RNA transport
Gene Ontology
GO Type GO Id Gene Ontology
Biological Process GO:0006974 cellular response to DNA damage stimulus
Biological Process GO:0072711 cellular response to hydroxyurea
Biological Process GO:0034644 cellular response to UV
Biological Process GO:0098586 cellular response to virus
Biological Process GO:0031047 gene silencing by RNA
Biological Process GO:0007215 glutamate receptor signaling pathway
Biological Process GO:0044830 modulation by host of viral RNA genome replication
Biological Process GO:0006397 mRNA processing
Biological Process GO:0051028 mRNA transport
Biological Process GO:2000766 negative regulation of cytoplasmic translation
Biological Process GO:1900453 negative regulation of long-term synaptic depression
Biological Process GO:1902373 negative regulation of mRNA catabolic process
Biological Process GO:2000301 negative regulation of synaptic vesicle exocytosis
Biological Process GO:0017148 negative regulation of translation
Biological Process GO:0045947 negative regulation of translational initiation
Biological Process GO:1901386 negative regulation of voltage-gated calcium channel activity
Biological Process GO:0060999 positive regulation of dendritic spine development
Biological Process GO:0051491 positive regulation of filopodium assembly
Biological Process GO:2000637 positive regulation of gene silencing by miRNA
Biological Process GO:0033129 positive regulation of histone phosphorylation
Biological Process GO:1901254 positive regulation of intracellular transport of viral material
Biological Process GO:1902416 positive regulation of mRNA binding
Biological Process GO:1901800 positive regulation of proteasomal protein catabolic process
Biological Process GO:0001934 positive regulation of protein phosphorylation
Biological Process GO:0002092 positive regulation of receptor internalization
Biological Process GO:2001022 positive regulation of response to DNA damage stimulus
Biological Process GO:0045727 positive regulation of translation
Biological Process GO:0000381 regulation of alternative mRNA splicing, via spliceosome
Biological Process GO:0060998 regulation of dendritic spine development
Biological Process GO:0051489 regulation of filopodium assembly
Biological Process GO:0060964 regulation of gene silencing by miRNA
Biological Process GO:0043488 regulation of mRNA stability
Biological Process GO:0098908 regulation of neuronal action potential
Biological Process GO:0046928 regulation of neurotransmitter secretion
Biological Process GO:0008380 RNA splicing
Biological Process GO:0016032 viral process
molecular function GO:0003682 chromatin binding
molecular function GO:0070840 dynein complex binding
molecular function GO:0002151 G-quadruplex RNA binding
molecular function GO:0042802 identical protein binding
molecular function GO:0044325 ion channel binding
molecular function GO:0035064 methylated histone binding
molecular function GO:0008017 microtubule binding
molecular function GO:0035198 miRNA binding
molecular function GO:0003730 mRNA 3'-UTR binding
molecular function GO:0048027 mRNA 5'-UTR binding
molecular function GO:0003729 mRNA binding
molecular function GO:0034046 poly(G) binding
molecular function GO:0008266 poly(U) RNA binding
molecular function GO:0046982 protein heterodimerization activity
molecular function GO:0042803 protein homodimerization activity
molecular function GO:0043022 ribosome binding
molecular function GO:0003723 RNA binding
molecular function GO:0035613 RNA stem-loop binding
molecular function GO:0033592 RNA strand annealing activity
molecular function GO:1990825 sequence-specific mRNA binding
molecular function GO:0035197 siRNA binding
molecular function GO:0031369 translation initiation factor binding
molecular function GO:0045182 translation regulator activity
molecular function GO:0030371 translation repressor activity
cellular component GO:0030424 axon
cellular component GO:0043679 axon terminus
cellular component GO:0015030 Cajal body
cellular component GO:0042995 cell projection
cellular component GO:0010369 chromocenter
cellular component GO:0005694 chromosome
cellular component GO:0000775 chromosome, centromeric region
cellular component GO:0005737 cytoplasm
cellular component GO:0036464 cytoplasmic ribonucleoprotein granule
cellular component GO:0010494 cytoplasmic stress granule
cellular component GO:0005829 cytosol
cellular component GO:0030425 dendrite
cellular component GO:1902737 dendritic filopodium
cellular component GO:0043197 dendritic spine
cellular component GO:0044326 dendritic spine neck
cellular component GO:0019897 extrinsic component of plasma membrane
cellular component GO:0032433 filopodium tip
cellular component GO:0097386 glial cell projection
cellular component GO:0030426 growth cone
cellular component GO:1990812 growth cone filopodium
cellular component GO:0016020 membrane
cellular component GO:1990124 messenger ribonucleoprotein complex
cellular component GO:0005845 mRNA cap binding complex
cellular component GO:0043025 neuronal cell body
cellular component GO:0071598 neuronal ribonucleoprotein granule
cellular component GO:0043005 neuron projection
cellular component GO:0005730 nucleolus
cellular component GO:0005654 nucleoplasm
cellular component GO:0005634 nucleus
cellular component GO:0043204 perikaryon
cellular component GO:0048471 perinuclear region of cytoplasm
cellular component GO:0005844 polysome
cellular component GO:0098794 postsynapse
cellular component GO:0014069 postsynaptic density
cellular component GO:0045211 postsynaptic membrane
cellular component GO:0098793 presynapse
cellular component GO:0042734 presynaptic membrane
cellular component GO:1990904 ribonucleoprotein complex
cellular component GO:0035770 ribonucleoprotein granule
cellular component GO:0045202 synapse
cellular component GO:0019034 viral replication complex
Reactome
Pathway Id Pathway Name
Target protein-related  diseases
Disease
CUI Id BXGD Id Disease Name Disease Class
C0000768 BXGD000007 Congenital Abnormality Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0002395 BXGD000111 Alzheimer's Disease Nervous System Diseases; Mental Disorders
C0002622 BXGD000119 Amnesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0002736 BXGD000127 Amyotrophic Lateral Sclerosis Nutritional and Metabolic Diseases; Nervous System Diseases
C0003467 BXGD000194 Anxiety Behavior and Behavior Mechanisms
C0003469 BXGD000195 Anxiety Disorders Mental Disorders
C0004096 BXGD000252 Asthma Respiratory Tract Diseases; Immune System Diseases
C0004114 BXGD000255 Astrocytoma Neoplasms
C0004134 BXGD000256 Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0004352 BXGD000269 Autistic Disorder Mental Disorders
C0004364 BXGD000270 Autoimmune Diseases Immune System Diseases
C0004444 BXGD000274 Avoidant Personality Disorder Mental Disorders
C0004930 BXGD000294 Behavior Disorders Mental Disorders
C0004936 BXGD000295 Mental disorders Mental Disorders
C0004941 BXGD000296 Behavioral Symptoms Behavior and Behavior Mechanisms
C0005586 BXGD000315 Bipolar Disorder Mental Disorders
C0006142 BXGD000374 Malignant neoplasm of breast Neoplasms; Skin and Connective Tissue Diseases
C0006826 BXGD000408 Malignant Neoplasms Neoplasms
C0007758 BXGD000475 Cerebellar Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0007760 BXGD000476 Cerebellar Diseases Nervous System Diseases
C0007787 BXGD000487 Transient Ischemic Attack Nervous System Diseases; Cardiovascular Diseases
C0008073 BXGD000518 Developmental Disabilities Mental Disorders
C0008626 BXGD000559 Congenital chromosomal disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0009241 BXGD000595 Cognition Disorders Mental Disorders
C0009946 BXGD000638 Conversion disorder Mental Disorders
C0010417 BXGD000670 Cryptorchidism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Male Urogenital Diseases; Endocrine System Diseases
C0011168 BXGD000700 Deglutition Disorders Digestive System Diseases; Otorhinolaryngologic Diseases
C0011265 BXGD000708 Presenile dementia Nervous System Diseases; Mental Disorders
C0011570 BXGD000729 Mental Depression Behavior and Behavior Mechanisms
C0011581 BXGD000733 Depressive disorder Mental Disorders
C0011854 BXGD000753 Diabetes Mellitus, Insulin-Dependent Nutritional and Metabolic Diseases; Immune System Diseases; Endocrine System Diseases
C0012746 BXGD000787 Dissociative disorder Mental Disorders
C0013080 BXGD000797 Down Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0013170 BXGD000802 Drug habituation Chemically-Induced Disorders; Mental Disorders
C0013336 BXGD000815 Dwarfism Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Endocrine System Diseases
C0013362 BXGD000817 Dysarthria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0013363 BXGD000818 Dysautonomia Nervous System Diseases
C0014544 BXGD000926 Epilepsy Nervous System Diseases
C0015544 BXGD001003 Failure to Thrive Pathological Conditions, Signs and Symptoms
C0015732 BXGD001018 Fecal Incontinence Digestive System Diseases
C0015934 BXGD001026 Fetal Growth Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications
C0016053 BXGD001041 Fibromyalgia Musculoskeletal Diseases; Nervous System Diseases
C0016202 BXGD001050 Flatfoot Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0016667 BXGD001072 Fragile X Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0016842 BXGD001083 Congenital pectus excavatum Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0017168 BXGD001101 Gastroesophageal reflux disease Digestive System Diseases
C0018051 BXGD001167 Gonadal Dysgenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0018213 BXGD001187 Graves Disease Eye Diseases; Immune System Diseases; Endocrine System Diseases
C0018418 BXGD001192 Gynecomastia Skin and Connective Tissue Diseases
C0018524 BXGD001200 Hallucinations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0018817 BXGD001235 Atrial Septal Defects Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C0020179 BXGD001363 Huntington Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders
C0020538 BXGD001422 Hypertensive disease Cardiovascular Diseases
C0020619 BXGD001447 Hypogonadism Endocrine System Diseases
C0020626 BXGD001452 Hypoparathyroidism Endocrine System Diseases
C0020649 BXGD001459 Hypotension Cardiovascular Diseases
C0020676 BXGD001462 Hypothyroidism Endocrine System Diseases
C0020757 BXGD001466 Ichthyoses Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0020758 BXGD001467 Congenital ichthyosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Skin and Connective Tissue Diseases
C0020796 BXGD001468 Profound Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0022735 BXGD001581 Klinefelter Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0023895 BXGD001717 Liver diseases Digestive System Diseases
C0023903 BXGD001720 Liver neoplasms Digestive System Diseases; Neoplasms
C0024121 BXGD001735 Lung Neoplasms Neoplasms; Respiratory Tract Diseases
C0024141 BXGD001740 Lupus Erythematosus, Systemic Skin and Connective Tissue Diseases; Immune System Diseases
C0025202 BXGD001832 melanoma Neoplasms
C0025322 BXGD001863 Premature Menopause Female Urogenital Diseases and Pregnancy Complications
C0025362 BXGD001866 Mental Retardation Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025363 BXGD001867 Mental Retardation, Psychosocial Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0025517 BXGD001875 Metabolic Diseases Nutritional and Metabolic Diseases
C0026106 BXGD001889 Mild Mental Retardation Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026267 BXGD001896 Mitral Valve Prolapse Syndrome Cardiovascular Diseases
C0026351 BXGD001900 Moderate intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0026650 BXGD001913 Movement Disorders Nervous System Diseases
C0026705 BXGD001920 Mucopolysaccharidosis II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases; Nervous System Diseases
C0026769 BXGD001930 Multiple Sclerosis Immune System Diseases; Nervous System Diseases
C0026827 BXGD001936 Muscle hypotonia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0026837 BXGD001937 Muscle Rigidity Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0026850 BXGD001942 Muscular Dystrophy Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0027627 BXGD002006 Neoplasm Metastasis Pathological Conditions, Signs and Symptoms; Neoplasms
C0027651 BXGD002009 Neoplasms Neoplasms
C0027765 BXGD002033 nervous system disorder Nervous System Diseases
C0027819 BXGD002043 Neuroblastoma Neoplasms
C0027831 BXGD002047 Neurofibromatosis 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0028738 BXGD002081 Nystagmus Eye Diseases; Nervous System Diseases
C0030193 BXGD002191 Pain Pathological Conditions, Signs and Symptoms
C0030567 BXGD002240 Parkinson Disease Nervous System Diseases
C0031572 BXGD002307 Phobia, Social Mental Disorders
C0032460 BXGD002355 Polycystic Ovary Syndrome Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0032580 BXGD002362 Adenomatous Polyposis Coli Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms
C0032897 BXGD002378 Prader-Willi Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C0033626 BXGD002412 Protein Deficiency Nutritional and Metabolic Diseases
C0033975 BXGD002447 Psychotic Disorders Mental Disorders
C0034013 BXGD002450 Precocious Puberty Endocrine System Diseases
C0035258 BXGD002523 Restless Legs Syndrome Nervous System Diseases; Mental Disorders
C0035372 BXGD002544 Rett Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0036341 BXGD002600 Schizophrenia Mental Disorders
C0036439 BXGD002615 Scoliosis, unspecified Musculoskeletal Diseases
C0036572 BXGD002625 Seizures Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0036857 BXGD002638 Severe intellectual disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037199 BXGD002671 Sinusitis Infections; Respiratory Tract Diseases; Otorhinolaryngologic Diseases
C0037315 BXGD002687 Sleep Apnea Syndromes Respiratory Tract Diseases; Nervous System Diseases
C0037317 BXGD002689 Sleep disturbances Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0037822 BXGD002706 Speech Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038220 BXGD002740 Status Epilepticus Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0038379 BXGD002752 Strabismus Eye Diseases; Nervous System Diseases
C0038436 BXGD002755 Post-Traumatic Stress Disorder Mental Disorders
C0038443 BXGD002757 Stress, Psychological Behavior and Behavior Mechanisms
C0038868 BXGD002781 Progressive supranuclear palsy Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0040822 BXGD002885 Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0041341 BXGD002918 Tuberous Sclerosis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Nervous System Diseases
C0041696 BXGD002932 Unipolar Depression Mental Disorders
C0042023 BXGD002948 Increased frequency of micturition Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042024 BXGD002949 Urinary Incontinence Pathological Conditions, Signs and Symptoms; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases
C0042373 BXGD002978 Vascular Diseases Cardiovascular Diseases
C0079588 BXGD003084 Ichthyosis, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C0079731 BXGD003087 B-Cell Lymphomas Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases
C0085215 BXGD003141 Ovarian Failure, Premature Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0085271 BXGD003148 Self-Injurious Behavior Behavior and Behavior Mechanisms
C0086132 BXGD003264 Depressive Symptoms Behavior and Behavior Mechanisms
C0086367 BXGD003276 Gonadotropin-Resistant Ovary Syndrome Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0086437 BXGD003282 Joint laxity Musculoskeletal Diseases
C0087012 BXGD003318 Ataxia, Spinocerebellar Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0149931 BXGD003388 Migraine Disorders Nervous System Diseases
C0151786 BXGD003475 Muscle Weakness Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0151888 BXGD003497 Hyporeflexia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0152421 BXGD003586 Macrotia
C0153676 BXGD003679 Secondary malignant neoplasm of lung Neoplasms; Respiratory Tract Diseases
C0154208 BXGD003707 Disorder of endocrine ovary Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0156404 BXGD003857 Irregular Menstruation Pathological Conditions, Signs and Symptoms
C0162635 BXGD003964 Angelman Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0175702 BXGD004008 Williams Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases; Cardiovascular Diseases
C0178874 BXGD004037 Tumor Progression Pathological Conditions, Signs and Symptoms
C0220769 BXGD004343 FG syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nervous System Diseases
C0221354 BXGD004446 Frontal bossing Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0221355 BXGD004447 Macrocephaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases
C0231528 BXGD004496 Myalgia Pathological Conditions, Signs and Symptoms; Musculoskeletal Diseases; Nervous System Diseases
C0232940 BXGD004569 Secondary physiologic amenorrhea Pathological Conditions, Signs and Symptoms
C0233397 BXGD004574 Psychological symptom
C0233401 BXGD004575 Psychiatric symptom
C0233514 BXGD004584 Abnormal behavior Behavior and Behavior Mechanisms
C0233565 BXGD004590 Bradykinesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0233794 BXGD004618 Memory impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0234162 BXGD004627 Cerebellar Dysmetria Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234376 BXGD004659 Action Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234378 BXGD004661 Static Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234379 BXGD004662 Resting Tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234410 BXGD004665 Physiologic disinhibition
C0234979 BXGD004707 Dysdiadochokinesis Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0234985 BXGD004708 Mental deterioration Mental Disorders
C0235031 BXGD004714 Neurologic Symptoms Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0235946 BXGD004789 Cerebral atrophy Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0236642 BXGD004815 Pick Disease of the Brain Nervous System Diseases; Mental Disorders
C0236794 BXGD004831 Panic disorder without agoraphobia Mental Disorders
C0236801 BXGD004834 Phobia, Specific Mental Disorders
C0236818 BXGD004839 Selective Mutism Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0240543 BXGD005042 Bulbous nose
C0241355 BXGD005092 Small testicle
C0241703 BXGD005109 High pitched voice
C0242350 BXGD005154 Erectile dysfunction Male Urogenital Diseases; Mental Disorders
C0242422 BXGD005163 Parkinsonian Disorders Nervous System Diseases
C0262405 BXGD005237 Cerebral dysfunction Nervous System Diseases
C0265354 BXGD005529 CHARGE Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Eye Diseases
C0266617 BXGD005700 Congenital anomaly of face Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Musculoskeletal Diseases
C0270612 BXGD006081 Leukoencephalopathy Nervous System Diseases
C0270736 BXGD006096 Essential Tremor Nervous System Diseases
C0271441 BXGD006203 Chronic otitis media Otorhinolaryngologic Diseases
C0271737 BXGD006252 Addison's disease due to autoimmunity Immune System Diseases; Endocrine System Diseases
C0276289 BXGD006418 Zika Virus Infection Infections
C0278061 BXGD006492 Abnormal mental state Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0278883 BXGD006614 Metastatic melanoma Neoplasms
C0282631 BXGD006821 Facies Pathological Conditions, Signs and Symptoms
C0338451 BXGD007176 Frontotemporal dementia Nutritional and Metabolic Diseases; Nervous System Diseases; Mental Disorders
C0338656 BXGD007211 Impaired cognition Mental Disorders
C0338908 BXGD007218 Mixed anxiety and depressive disorder Mental Disorders
C0342409 BXGD007476 Hypophysitis Nervous System Diseases; Endocrine System Diseases
C0344315 BXGD007666 Depressed mood Behavior and Behavior Mechanisms
C0349204 BXGD007892 Nonorganic psychosis Mental Disorders
C0349588 BXGD007933 Short stature
C0376280 BXGD007983 Anxiety States, Neurotic Mental Disorders
C0376532 BXGD008000 Epilepsy, Rolandic Nervous System Diseases
C0376545 BXGD008002 Hematologic Neoplasms Neoplasms; Hemic and Lymphatic Diseases
C0376634 BXGD008006 Craniofacial Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases
C0392699 BXGD008064 Dysesthesia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0393524 BXGD008080 Cerebellar Ataxia, Late Onset Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0393591 BXGD008102 AICARDI-GOUTIERES SYNDROME Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Immune System Diseases; Nervous System Diseases
C0399526 BXGD008251 Class III malocclusion Stomatognathic Diseases
C0423224 BXGD008475 Sunken eyes Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
C0424101 BXGD008519 Inattention
C0424166 BXGD008521 Social Anxiety Behavior and Behavior Mechanisms
C0424295 BXGD008524 Hyperactive behavior Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0424296 BXGD008525 Social disinhibition Mental Disorders
C0424448 BXGD008529 Mask-like facies Nervous System Diseases
C0424605 BXGD008535 Developmental delay (disorder) Mental Disorders
C0426980 BXGD008599 Motor symptoms
C0432072 BXGD008718 Dysmorphic features
C0432474 BXGD008793 Klinefelter's syndrome - male with more than two X chromosomes Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C0432482 BXGD008795 Fragile X chromosome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0442874 BXGD008814 Neuropathy Nervous System Diseases
C0476217 BXGD008980 Head movements abnormal Nervous System Diseases
C0476236 BXGD008982 Developmental symptoms
C0497327 BXGD009061 Dementia Nervous System Diseases; Mental Disorders
C0524528 BXGD009229 Pervasive Development Disorder Mental Disorders
C0524851 BXGD009246 Neurodegenerative Disorders Nervous System Diseases
C0525041 BXGD009254 Neurobehavioral Manifestations Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0525045 BXGD009255 Mood Disorders Mental Disorders
C0541764 BXGD009259 Delayed bone age
C0542476 BXGD009276 Forgetful Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0557874 BXGD009444 Global developmental delay
C0575802 BXGD009521 Small hand
C0576226 BXGD009527 Short foot
C0578038 BXGD009542 Thin lips
C0596263 BXGD009639 Carcinogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0598275 BXGD009664 Diffuse cerebral atrophy Nervous System Diseases; Mental Disorders
C0598766 BXGD009669 Leukemogenesis Pathological Conditions, Signs and Symptoms; Neoplasms
C0600104 BXGD009690 Obsessive compulsive behavior Behavior and Behavior Mechanisms
C0677886 BXGD009734 Epithelial ovarian cancer Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0678222 BXGD009749 Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C0679378 BXGD009768 neurodevelopmental anomaly Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C0683322 BXGD009782 Mental impairment
C0687131 BXGD009838 Psychoticism
C0700095 BXGD009875 Central neuroblastoma Neoplasms; Nervous System Diseases
C0700201 BXGD009880 Dyssomnias Nervous System Diseases; Mental Disorders
C0740279 BXGD009973 Cerebellar atrophy
C0742035 BXGD010053 Cerebellar lesion NOS
C0743101 BXGD010076 developmentally delayed
C0743479 BXGD010083 emotional dysfunction
C0747102 BXGD010159 Ovarian failure Endocrine System Diseases
C0748071 BXGD010190 psychosocial impairment
C0751156 BXGD010332 FRAXA Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751157 BXGD010333 FRAXE Syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0751265 BXGD010370 Learning Disabilities Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0751295 BXGD010383 Memory Loss Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Behavior and Behavior Mechanisms
C0751791 BXGD010595 Reflex Epilepsy, Audiogenic Nervous System Diseases
C0751837 BXGD010604 Gait Ataxia Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C0795864 BXGD010754 Smith-Magenis syndrome Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0796135 BXGD010802 Renpenning syndrome 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C0851121 BXGD010913 digestive problem
C0851578 BXGD010925 Sleep Disorders Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders
C0856747 BXGD011112 Aneurysm of ascending aorta Respiratory Tract Diseases; Cardiovascular Diseases
C0856975 BXGD011127 Autistic behavior Behavior and Behavior Mechanisms
C0860603 BXGD011236 Anxiety symptoms
C0917816 BXGD011419 Mental deficiency Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C0919267 BXGD011426 ovarian neoplasm Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C0947785 BXGD011495 [D]Sleep disturbances (& [hypersomnia] or [insomnia])
C0949331 BXGD011574 Gonadal Agenesis Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Male Urogenital Diseases; Endocrine System Diseases
C1136249 BXGD011715 Mental Retardation, X-Linked Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1140680 BXGD011718 Malignant neoplasm of ovary Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C1263023 BXGD011888 Macroorchidism
C1263846 BXGD011897 Attention deficit hyperactivity disorder Mental Disorders
C1269683 BXGD012001 Major Depressive Disorder Mental Disorders
C1269955 BXGD012005 Tumor Cell Invasion
C1279420 BXGD012122 Anxiety neurosis (finding) Mental Disorders
C1285162 BXGD012167 Degenerative disorder Pathological Conditions, Signs and Symptoms
C1306341 BXGD012360 Mental handicap
C1306459 BXGD012361 Primary malignant neoplasm Neoplasms
C1333990 BXGD012670 Hereditary Nonpolyposis Colorectal Cancer Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Neoplasms; Nutritional and Metabolic Diseases
C1364667 BXGD012880 Adrenalitis
C1384666 BXGD012948 hearing impairment Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Otorhinolaryngologic Diseases
C1401084 BXGD013014 Ovarian Insufficiency
C1445953 BXGD013080 Poor eye contact Mental Disorders
C1456326 BXGD013114 Selective mutism specific to childhood and adolescence
C1510586 BXGD013176 Autism Spectrum Disorders Mental Disorders
C1527336 BXGD013271 Sjogren's Syndrome Eye Diseases; Skin and Connective Tissue Diseases; Musculoskeletal Diseases; Immune System Diseases; Stomatognathic Diseases
C1535926 BXGD013322 Neurodevelopmental Disorders Mental Disorders
C1536114 BXGD013336 Central pain syndrome Nervous System Diseases
C1611743 BXGD013456 Familial (FPAH)
C1737329 BXGD013728 Dysmorphism Congenital, Hereditary, and Neonatal Diseases and Abnormalities
C1739395 BXGD013739 Takotsubo Cardiomyopathy Cardiovascular Diseases
C1834433 BXGD013973 Obsessive-compulsive trait Behavior and Behavior Mechanisms
C1836047 BXGD014074 Long face
C1836479 BXGD014121 Saccadic smooth pursuit
C1837249 BXGD014210 Malformations of Cortical Development, Group II Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1837463 BXGD014235 Narrow face
C1839780 BXGD014405 FRAGILE X TREMOR/ATAXIA SYNDROME Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1839782 BXGD014406 Macroorchidism, postpubertal
C1839783 BXGD014407 Large forehead
C1839785 BXGD014408 Folate-dependent fragile site at Xq28 Pathological Conditions, Signs and Symptoms
C1842605 BXGD014527 SCHIZOPHRENIA 11
C1843367 BXGD014576 Poor school performance
C1843663 BXGD014600 Urinary bladder sphincter dysfunction
C1845847 BXGD014760 Coarse facial features Pathological Conditions, Signs and Symptoms
C1847879 BXGD014895 X-linked dominant inheritance
C1848673 BXGD014963 Hypoplastic feet
C1850601 BXGD015159 Abnormality of brainstem morphology
C1853767 BXGD015361 Impaired distal vibration sensation
C1854699 BXGD015425 Diffuse cerebellar atrophy
C1854919 BXGD015442 Severe psychomotor retardation
C1855285 BXGD015483 Protruding ear
C1856689 BXGD015630 FRIEDREICH ATAXIA 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
C1857276 BXGD015688 Trichohepatoenteric Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Female Urogenital Diseases and Pregnancy Complications; Skin and Connective Tissue Diseases
C1860787 BXGD015997 DOWN SYNDROME CRITICAL REGION Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1862265 BXGD016119 Increased circulating gonadotropin level Nervous System Diseases; Endocrine System Diseases
C1862389 BXGD016126 ATRIAL SEPTAL DEFECT 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cardiovascular Diseases
C1862863 BXGD016138 Sparse body hair
C1863843 BXGD016199 Neuronal intranuclear inclusion disease Nervous System Diseases
C1864172 BXGD016217 Peroxisome Biogenesis Disorder, Complementation Group G Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases
C1867864 BXGD016472 Poor fine motor coordination
C1868193 BXGD016493 PNEUMOTHORAX, PRIMARY SPONTANEOUS
C1868720 BXGD016531 Periventricular Nodular Heterotopia Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C1963167 BXGD016686 Memory Impairment, CTCAE 3.0
C1963184 BXGD016688 Nystagmus, CTCAE 3.0
C2239176 BXGD016965 Liver carcinoma Digestive System Diseases; Neoplasms
C2363129 BXGD017095 Benign Rolandic Epilepsy Nervous System Diseases
C2678248 BXGD017401 Mood instability
C2720163 BXGD017530 Placental Steroid Sulfatase Deficiency Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Skin and Connective Tissue Diseases
C2748208 BXGD017586 Executive dysfunction
C2751898 BXGD017749 Ventricular Fibrillation, Paroxysmal Familial, 1 Pathological Conditions, Signs and Symptoms; Cardiovascular Diseases
C2919142 BXGD017867 Short Stature, CTCAE
C2930861 BXGD017905 Premature ovarian failure, familial Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C2931498 BXGD018030 Mental Retardation, X-Linked 1 Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C3160718 BXGD018468 PARKINSON DISEASE, LATE-ONSET
C3264595 BXGD018593 Agoraphobia without panic disorder Mental Disorders
C3275367 BXGD018661 Impaired tandem gait
C3275521 BXGD018672 CHROMOSOME Xq27.3-q28 DUPLICATION SYNDROME
C3494522 BXGD018969 Hypergonadotropic Ovarian Failure, X-Linked Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C3539878 BXGD019087 Triple Negative Breast Neoplasms Neoplasms; Skin and Connective Tissue Diseases
C3714756 BXGD019429 Intellectual Disability Pathological Conditions, Signs and Symptoms; Nervous System Diseases; Mental Disorders; Behavior and Behavior Mechanisms
C3809278 BXGD019579 EPILEPTIC ENCEPHALOPATHY, CHILDHOOD-ONSET
C3825158 BXGD019683 Learning disabled
C3839507 BXGD019774 Diminished ovarian reserve Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4020732 BXGD020474 Mitochondrial abnormalities
C4021768 BXGD020766 Abnormality of metabolism/homeostasis
C4022575 BXGD020921 Inertia
C4024650 BXGD021358 Congenital macroorchidism
C4086152 BXGD022123 Childhood Astrocytoma Neoplasms
C4086165 BXGD022126 Childhood Neuroblastoma Neoplasms
C4285807 BXGD022455 Behavioral and psychological symptoms of dementia
C4302185 BXGD022525 Atypical Parkinsonism Nervous System Diseases
C4303510 BXGD022563 Idiopathic premature ovarian failure Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4324720 BXGD022778 Autoimmune thyroid disorder
C4521042 BXGD023055 Complete Trisomy 21 Syndrome Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nervous System Diseases
C4551520 BXGD023336 Intention tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4551521 BXGD023337 Kinetic tremor Pathological Conditions, Signs and Symptoms; Nervous System Diseases
C4551560 BXGD023349 Truncal obesity Pathological Conditions, Signs and Symptoms; Nutritional and Metabolic Diseases
C4551583 BXGD023361 Cerebral cortical atrophy
C4551584 BXGD023362 Brain atrophy Nervous System Diseases
C4552079 BXGD023483 Premature Ovarian Failure 1 Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4552213 BXGD023495 Broad autism phenotype
C4552766 BXGD023523 Miscarriage Female Urogenital Diseases and Pregnancy Complications
C4553765 BXGD023551 Memory Impairment, CTCAE 5.0
C4554036 BXGD023557 Nystagmus, CTCAE 5.0
C4721453 BXGD023744 Peripheral Nervous System Diseases Nervous System Diseases
C4721610 BXGD023760 Carcinoma, Ovarian Epithelial Neoplasms; Female Urogenital Diseases and Pregnancy Complications; Endocrine System Diseases
C4722518 BXGD023806 Triple-Negative Breast Carcinoma Neoplasms; Skin and Connective Tissue Diseases
C4732730 BXGD023895 Blood spots
Target protein-related  compounds
Compounds
BXGC Id Compound Name Strcuture Molecular Weight
BXGC0002588 Magnesium 24.31
BXGC0002702 Lead 207.2
The  target protein-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compound? Number of compound in food, higher numbers indicate the food are more associated with the protein